Search Results - "Melhorn, Susan J."

Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and toll-like receptor activation by Roth, Christian L., Elfers, Clinton T., Figlewicz, Dianne P., Melhorn, Susan J., Morton, Gregory J., Hoofnagle, Andrew, Yeh, Matthew M., Nelson, James E., Kowdley, Kris V.

“…Childhood obesity is associated with type 2 diabetes mellitus and nonalcoholic fatty liver disease (NAFLD). Recent studies have found associations between…”
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Effects of Chronic Social Stress on Obesity by Scott, Karen A., Melhorn, Susan J., Sakai, Randall R.

“…The prevalence of overweight and obesity has markedly increased during the past few decades. Stress has been suggested as one environmental factor that may…”
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Effects of Anxiety on Caloric Intake and Satiety-Related Brain Activation in Women and Men by Mestre, Zoe Lucille, Melhorn, Susan J, Askren, Mary K, Tyagi, Vidhi, Gatenby, Christopher, Young, Liza, Mehta, Sonya, Webb, Mary F, Grabowski, Thomas J, Schur, Ellen A

“…To test the relationship of anxiety to caloric intake and food cue perception in women and men. Fifty-five twins (26 complete, 3 incomplete pairs; 51% women)…”
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Acute exposure to a high-fat diet alters meal patterns and body composition by Melhorn, Susan J, Krause, Eric G, Scott, Karen A, Mooney, Marie R, Johnson, Jeffrey D, Woods, Stephen C, Sakai, Randall R

“…Abstract Weight gain and adiposity are often attributed to the overconsumption of unbalanced, high-fat diets however, the pattern of consumption can also…”
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Dynamic body weight and body composition changes in response to subordination stress by Tamashiro, Kellie L.K, Hegeman, Maria A, Nguyen, Mary M.N, Melhorn, Susan J, Ma, Li Yun, Woods, Stephen C, Sakai, Randall R

“…Abstract Social stress is prevalent in many facets of modern society. Epidemiological data suggest that stress is linked to the development of overweight,…”
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Angiotensin Type 1 Receptors in the Subfornical Organ Mediate the Drinking and Hypothalamic-Pituitary-Adrenal Response to Systemic Isoproterenol by Krause, Eric G, Melhorn, Susan J, Davis, Jon F, Scott, Karen A, Ma, Li Y, de Kloet, Annette D, Benoit, Stephen C, Woods, Stephen C, Sakai, Randall R

“…Circulating angiotensin II (ANGII) elicits water intake and activates the hypothalamic-pituitary-adrenal (HPA) axis by stimulating angiotensin type 1 receptors…”
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The Significance of Hypothalamic Inflammation and Gliosis for the Pathogenesis of Obesity in Humans by Sewaybricker, Leticia E, Huang, Alyssa, Chandrasekaran, Suchitra, Melhorn, Susan J, Schur, Ellen A

“…Abstract Accumulated preclinical literature demonstrates that hypothalamic inflammation and gliosis are underlying causal components of diet-induced obesity in…”
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Using Make for Reproducible and Parallel Neuroimaging Workflow and Quality-Assurance by Askren, Mary K, McAllister-Day, Trevor K, Koh, Natalie, Mestre, Zoé, Dines, Jennifer N, Korman, Benjamin A, Melhorn, Susan J, Peterson, Daniel J, Peverill, Matthew, Qin, Xiaoyan, Rane, Swati D, Reilly, Melissa A, Reiter, Maya A, Sambrook, Kelly A, Woelfer, Karl A, Grabowski, Thomas J, Madhyastha, Tara M

“…The contribution of this paper is to describe how we can program neuroimaging workflow using Make, a software development tool designed for describing how to…”
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Greater radiologic evidence of hypothalamic gliosis predicts adiposity gain in children at risk for obesity by Sewaybricker, Leticia E., Kee, Sarah, Melhorn, Susan J., Schur, Ellen A.

“…Objective This study investigated, in a large pediatric population, whether magnetic resonance imaging (MRI) evidence of mediobasal hypothalamic (MBH) gliosis…”
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346-OR: Hypothalamic Gliosis Is Associated with CVD Risk Factors in the Framingham Heart Study (FHS) by LO, JUSTIN, MELHORN, SUSAN J., OLERICH, KELSEY, HUANG, ALYSSA, KEE, SARAH, BEISER, ALEXA, SESHADRI, SUDHA, DECARLI, CHARLES, SCHUR, ELLEN

“…Introduction: Hypothalamic gliosis is linked to obesity and insulin resistance in rodent models and humans. We tested associations between a radiologic measure…”
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1269-P: A Prospective, Population-Based Study of Hypothalamic Gliosis, Obesity, and Weight Gain in Children by SEWAYBRICKER, LETICIA E., MELHORN, SUSAN J., SCHUR, ELLEN

“…Hypothalamic gliosis is a cellular response that, in rodents, is necessary for weight gain and diet-induced obesity. Whether this inflammatory process in the…”
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Regional brain response to visual food cues is a marker of satiety that predicts food choice by Mehta, Sonya, Melhorn, Susan J, Smeraglio, Anne, Tyagi, Vidhi, Grabowski, Thomas, Schwartz, Michael W, Schur, Ellen A

“…Background: Neuronal processes that underlie the subjective experience of satiety after a meal are not well defined.Objective: We investigated how satiety…”
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In utero exposure to maternal diabetes or hypertension and childhood hypothalamic gliosis by Olerich, Kelsey L. W., Sewaybricker, Leticia E., Kee, Sarah, Melhorn, Susan J., Chandrasekaran, Suchitra, Schur, Ellen A.

“…Exposure to maternal diabetes (DM) or hypertension (HTN) during pregnancy impacts offspring metabolic health in childhood and beyond. Animal models suggest…”
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343-OR: Maternal Diabetes Is Associated with Hypothalamic Gliosis in Offspring by SEWAYBRICKER, LETICIA E., OLERICH, KELSEY, KEE, SARAH L., MELHORN, SUSAN J., CHANDRASEKARAN, SUCHITRA, SCHUR, ELLEN

“…In utero exposure to gestational diabetes (GDM) or hypertension (HYP) is associated with child obesity. These maternal conditions alter the in utero milieu and…”
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FTO genotype impacts food intake and corticolimbic activation by Melhorn, Susan J, Askren, Mary K, Chung, Wendy K, Kratz, Mario, Bosch, Tyler A, Tyagi, Vidhi, Webb, Mary F, De Leon, Mary Rosalynn B, Grabowski, Thomas J, Leibel, Rudolph L, Schur, Ellen A

“…Variants in the first intron of the fat mass and obesity-associated (FTO) gene increase obesity risk. People with “high-risk” FTO genotypes exhibit preference…”
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Hypothalamic Gliosis Associated With High-Fat Diet Feeding Is Reversible in Mice: A Combined Immunohistochemical and Magnetic Resonance Imaging Study by Berkseth, Kathryn E, Guyenet, Stephan J, Melhorn, Susan J, Lee, Donghoon, Thaler, Joshua P, Schur, Ellen A, Schwartz, Michael W

“…Gliosis, the activation of astrocyte and microglial cell populations, is a hallmark of central nervous system injury and is detectable using either…”
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1714-P: Higher Initial Diet Quality Predicts Shorter Weight Loss Period prior to an Involuntary Weight Loss Plateau by MELHORN, SUSAN J., SEWAYBRICKER, LETICIA E., GAO, HUI, ROSALYNN DE LEON, MARY, WEBB, MARY, LYLE, MEGHAN, BEATTY, SARAH J., KRATZ, MARIO, SCHUR, ELLEN

“…It is currently unknown what factor(s) may promote entry into a weight loss plateau. Given intensive lifestyle interventions (ILI) for weight loss include…”
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Evidence That Hypothalamic Gliosis Is Related to Impaired Glucose Homeostasis in Adults With Obesity by Rosenbaum, Jennifer L, Melhorn, Susan J, Schoen, Stefan, Webb, Mary F, De Leon, Mary Rosalynn B, Humphreys, Madelaine, Utzschneider, Kristina M, Schur, Ellen A

“…Preclinical research implicates hypothalamic glial cell responses in the pathogenesis of obesity and type 2 diabetes (T2D). In the current study we sought to…”
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Radiologic evidence that hypothalamic gliosis is associated with obesity and insulin resistance in humans by Schur, Ellen A., Melhorn, Susan J., Oh, Seok‐Kyun, Lacy, J. Matthew, Berkseth, Kathryn E., Guyenet, Stephan J., Sonnen, Joshua A., Tyagi, Vidhi, Rosalynn, Mary, De Leon, B., Webb, Mary F., Gonsalves, Zenobia T., Fligner, Corinne L., Schwartz, Michael W., Maravilla, Kenneth R.

“…Objective To use quantitative magnetic resonance imaging (MRI) to test whether mediobasal hypothalamic (MBH) gliosis is associated with obesity and insulin…”
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151-OR: Radiologic Evidence that Hypothalamic Tissue Is Abnormal in Adults with Obesity and Type 2 Diabetes or Impaired Glucose Homeostasis by ROSENBAUM, JENNIFER L., SEWAYBRICKER, LETICIA E., CHANDRASEKARAN, SUCHITRA, DE LEON, MARY ROSALYNN, WEBB, MARY, MELHORN, SUSAN J., SCHUR, ELLEN

“…Gliosis, a cellular response to injury in neural tissue, is linked to diet-induced obesity in rodent models. Growing evidence also implicates reactive gliosis…”
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