Search Results - "Melhem, R"

Diffusion kurtosis imaging: an emerging technique for evaluating the microstructural environment of the brain by Steven, Andrew J, Zhuo, Jiachen, Melhem, Elias R

“…Diffusion kurtosis imaging is an emerging technique based on the non-gaussian diffusion of water in biologic systems. The purpose of this article is to…”
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Classification of brain tumor type and grade using MRI texture and shape in a machine learning scheme by Zacharaki, Evangelia I., Wang, Sumei, Chawla, Sanjeev, Soo Yoo, Dong, Wolf, Ronald, Melhem, Elias R., Davatzikos, Christos

“…The objective of this study is to investigate the use of pattern classification methods for distinguishing different types of brain tumors, such as primary…”
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GLISTR: Glioma Image Segmentation and Registration by Gooya, A., Pohl, K. M., Bilello, M., Cirillo, L., Biros, G., Melhem, E. R., Davatzikos, C.

“…We present a generative approach for simultaneously registering a probabilistic atlas of a healthy population to brain magnetic resonance (MR) scans showing…”
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MRI Guided Focused Ultrasound-Mediated Delivery of Therapeutic Cells to the Brain: A Review of the State-of-the-Art Methodology and Future Applications by Ahmed, Nabid, Gandhi, Dheeraj, Melhem, Elias R., Frenkel, Victor

“…Stem cell and immune cell therapies are being investigated as a potential therapeutic modality for CNS disorders, performing functions such as targeted drug or…”
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Anatomy of the median nerve and its clinical applications by Soubeyrand, M., Melhem, R., Protais, M., Artuso, M., Crézé, M.

“…The median nerve is a mixed sensory and motor nerve. It is classically described as the nerve of pronation, of thumb, index finger, middle finger and wrist…”
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Linear associations between clinically assessed upper motor neuron disease and diffusion tensor imaging metrics in amyotrophic lateral sclerosis by Woo, John H, Wang, Sumei, Melhem, Elias R, Gee, James C, Cucchiara, Andrew, McCluskey, Leo, Elman, Lauren

“…To assess the relationship between clinically assessed Upper Motor Neuron (UMN) disease in Amyotrophic Lateral Sclerosis (ALS) and local diffusion alterations…”
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Metabolic imaging of energy metabolism in traumatic brain injury using hyperpolarized [1-13C]pyruvate by DeVience, Stephen J., Lu, Xin, Proctor, Julie, Rangghran, Parisa, Melhem, Elias R., Gullapalli, Rao, Fiskum, Gary M., Mayer, Dirk

“…Traumatic brain injury (TBI) is known to cause perturbations in the energy metabolism of the brain, but current tests of metabolic activity are only indirect…”
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Power-aware scheduling for periodic real-time tasks by Aydin, H., Melhem, R., Mosse, D., Mejia-Alvarez, P.

“…We address power-aware scheduling of periodic tasks to reduce CPU energy consumption in hard real-time systems through dynamic voltage scaling. Our intertask…”
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MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma by Roccaro, Aldo M., Sacco, Antonio, Thompson, Brian, Leleu, Xavier, Azab, Abdel Kareem, Azab, Feda, Runnels, Judith, Jia, Xiaoying, Ngo, Hai T., Melhem, Molly R., Lin, Charles P., Ribatti, Domenico, Rollins, Barrett J., Witzig, Thomas E., Anderson, Kenneth C., Ghobrial, Irene M.

“…Detailed genomic studies have shown that cytogenetic abnormalities contribute to multiple myeloma (MM) pathogenesis and disease progression. Nevertheless,…”
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Imaging of glutamate neurotransmitter alterations in Alzheimer's disease by Haris, Mohammad, Nath, Kavindra, Cai, Kejia, Singh, Anup, Crescenzi, Rachelle, Kogan, Feliks, Verma, Gaurav, Reddy, Sanjana, Hariharan, Hari, Melhem, Elias R., Reddy, Ravinder

“…Glutamate (Glu) is a major excitatory neurotransmitter in the brain and has been shown to decrease in the early stages of Alzheimer's disease (AD). Using a…”
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Diffusion-tensor MR imaging and tractography: exploring brain microstructure and connectivity by Nucifora, Paolo G P, Verma, Ragini, Lee, Seung-Koo, Melhem, Elias R

“…Diffusion magnetic resonance (MR) imaging is evolving into a potent tool in the examination of the central nervous system. Although it is often used for the…”
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The University of Pennsylvania glioblastoma (UPenn-GBM) cohort: advanced MRI, clinical, genomics, & radiomics by Bakas, Spyridon, Sako, Chiharu, Akbari, Hamed, Bilello, Michel, Sotiras, Aristeidis, Shukla, Gaurav, Rudie, Jeffrey D., Santamaría, Natali Flores, Kazerooni, Anahita Fathi, Pati, Sarthak, Rathore, Saima, Mamourian, Elizabeth, Ha, Sung Min, Parker, William, Doshi, Jimit, Baid, Ujjwal, Bergman, Mark, Binder, Zev A., Verma, Ragini, Lustig, Robert A., Desai, Arati S., Bagley, Stephen J., Mourelatos, Zissimos, Morrissette, Jennifer, Watt, Christopher D., Brem, Steven, Wolf, Ronald L., Melhem, Elias R., Nasrallah, MacLean P., Mohan, Suyash, O’Rourke, Donald M., Davatzikos, Christos

“…Glioblastoma is the most common aggressive adult brain tumor. Numerous studies have reported results from either private institutional data or publicly…”
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Leftward asymmetry in relative fiber density of the arcuate fasciculus by Nucifora, Paolo G. P, Verma, Ragini, Melhem, Elias R, Gur, Raquel E, Gur, Ruben C

“…Left hemispheric language dominance is well established, but the structural substrate for this functional asymmetry is uncertain. We report a strong asymmetry…”
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Differentiation between glioblastomas and solitary brain metastases using diffusion tensor imaging by Wang, Sumei, Kim, Sungheon, Chawla, Sanjeev, Wolf, Ronald L., Zhang, Wei-Guo, O'Rourke, Donald M., Judy, Kevin D., Melhem, Elias R., Poptani, Harish

“…The purpose of this study is to determine whether diffusion tensor imaging (DTI) metrics including tensor shape measures such as linear and planar anisotropy…”
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Computer-Assisted Segmentation of White Matter Lesions in 3D MR Images Using Support Vector Machine by Lao, Zhiqiang, Shen, Dinggang, Liu, Dengfeng, Jawad, Abbas F, Melhem, Elias R, Launer, Lenore J, Bryan, R. Nick, Davatzikos, Christos

“…Rationale and Objectives Brain lesions, especially white matter lesions (WMLs), are associated with cardiac and vascular disease, but also with normal aging…”
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Gender-based analysis of cortical thickness and structural connectivity in Parkinson’s disease by Yadav, Santosh K., Kathiresan, Nagarajan, Mohan, Suyash, Vasileiou, Georgia, Singh, Anup, Kaura, Deepak, Melhem, Elias R., Gupta, Rakesh K., Wang, Ena, Marincola, Francesco M., Borthakur, Arijitt, Haris, Mohammad

“…Parkinson’s disease (PD) is a progressive neurological disorder and appears to have gender-specific symptoms. Studies have observed a higher frequency for…”
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Differentiation between Glioblastomas, Solitary Brain Metastases, and Primary Cerebral Lymphomas Using Diffusion Tensor and Dynamic Susceptibility Contrast-Enhanced MR Imaging by WANG, S, KIM, S, CHAWLA, S, WOLF, R. L, KNIPP, D. E, VOSSOUGH, A, O'ROURKE, D. M, JUDY, K. D, POPTANI, H, MELHEM, E. R

“…Glioblastomas, brain metastases, and PCLs may have similar enhancement patterns on MR imaging, making the differential diagnosis difficult or even impossible…”
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Diagnostic utility of diffusion tensor imaging in differentiating glioblastomas from brain metastases by Wang, S, Kim, S J, Poptani, H, Woo, J H, Mohan, S, Jin, R, Voluck, M R, O'Rourke, D M, Wolf, R L, Melhem, E R, Kim, S

“…Differentiation of glioblastomas and solitary brain metastases is an important clinical problem because the treatment strategy can differ significantly. The…”
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Motion Correction for Brain MRI Using Deep Learning and a Novel Hybrid Loss Function by Zhang, Lei, Wang, Xiaoke, Rawson, Michael, Balan, Radu, Herskovits, Edward H, Melhem, Elias R, Chang, Linda, Wang, Ze, Ernst, Thomas

“…Purpose: Motion-induced magnetic resonance imaging (MRI) artifacts can deteriorate image quality and reduce diagnostic accuracy, but motion by human subjects…”
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Intraaxial brain masses: MR imaging-based diagnostic strategy--initial experience by Al-Okaili, Riyadh N, Krejza, Jaroslaw, Woo, John H, Wolf, Ronald L, O'Rourke, Donald M, Judy, Kevin D, Poptani, Harish, Melhem, Elias R

“…To develop and retrospectively determine the accuracy of a magnetic resonance (MR) imaging strategy to differentiate intraaxial brain masses, with histologic…”
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