Search Results - "Melero, Cristina"

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane by Lauffer, Benjamin E.L, Melero, Cristina, Temkin, Paul, Lei, Cai, Hong, Wanjin, Kortemme, Tanja, von Zastrow, Mark

“…Postsynaptic density 95/discs large/zonus occludens-1 (PDZ) domain-interacting motifs, in addition to their well-established roles in protein scaffolding at…”
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CD200R1 immune checkpoint blockade by the first-in-human anti-CD200R1 antibody 23ME-00610: molecular mechanism and engineering of a surrogate antibody by Melero, Cristina, Budiardjo, S Jimmy, Daruwalla, Anahita, Larrabee, Lance, Ganichkin, Oleg, Heiler, Alexander J, Fenaux, Jill, Chung, Ben, Fuh, Germaine, Huang, Yao-Ming

“…Human CD200R1 (hCD200R1), an immune inhibitory receptor expressed predominantly on T cells and myeloid cells, was identified as a promising immuno-oncology…”
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Complementary Functions of Plant AP Endonucleases and AP Lyases during DNA Repair of Abasic Sites Arising from C:G Base Pairs by Jordano-Raya, Marina, Beltrán-Melero, Cristina, Moreno-Recio, M. Dolores, Martínez-Macías, M. Isabel, Ariza, Rafael R., Roldán-Arjona, Teresa, Córdoba-Cañero, Dolores

“…Abasic (apurinic/apyrimidinic, AP) sites are ubiquitous DNA lesions arising from spontaneous base loss and excision of damaged bases. They may be processed…”
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La perspectiva china del orden liberal internacional: ¿nuevo orden mundial? by Melero Escamilla, Cristina

“…El futuro del orden liberal internacional se encuentra en un estado de profunda transformación, impulsado en gran parte por el ascenso de China como una…”
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Educar en Derechos Humanos a través de vidas migrantes by Serván-Melero, Cristina

“…El presente trabajo plantea la relevancia en materia de educación en Derechos Humanos y de Sensibilización Intercultural de las historias de vida de las…”
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Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition by Melero, Cristina, Ollikainen, Noah, Harwood, Ian, Karpiak, Joel, Kortemme, Tanja

“…Reengineering protein–protein recognition is an important route to dissecting and controlling complex interaction networks. Experimental approaches have used…”
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23ME-00610, a genetically informed, first-in-class antibody targeting CD200R1 to enhance antitumor T cell function by Fenaux, Jill, Fang, Xin, Huang, Yao-ming, Melero, Cristina, Bonnans, Caroline, Lowe, Earth Light, Palumbo, Tiziana, Lay, Cecilia, Yi, Zuoan, Zhou, Aileen, Poggio, Mauro, Chung, Wei-Jen, Majeed, Sophia R., Glatt, Dylan, Chen, Alice, Schmidt, Maike, Lee, Clarissa C.

“…Immune checkpoint inhibition (ICI) has revolutionized cancer treatment; however, only a subset of patients benefit long term. Therefore, methods for…”
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Bringing rehabilitation home with an e-health platform to treat stroke patients: study protocol of a randomized clinical trial (RGS@home) by Mura, Anna, Maier, Martina, Ballester, Belén Rubio, De la Torre Costa, Javier, López-Luque, Judit, Gelineau, Axelle, Mandigout, Stephane, Ghatan, Per Hamid, Fiorillo, Raffaele, Antenucci, Fabrizio, Coolen, Ton, Chivite, Iñigo, Callen, Antonio, Landais, Hugo, Gómez, Olga Irina, Melero, Cristina, Brandi, Santiago, Domenech, Marc, Daviet, Jean-Christophe, Zucca, Riccardo, Verschure, Paul F. M. J.

“…BackgroundThere is a pressing need for scalable healthcare solutions and a shift in the rehabilitation paradigm from hospitals to homes to tackle the increase…”
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La necesidad de incorporar las competencias de comunicación en la formación de los enólogos by Juan Gómez Benítez, Melero, Cristina Lasanta, Lucía Benítez Eyzaguirre

“…The OIV has recently approved the resolutions OIV-ECO 492-2013 on the definition of the profession of oenologist and OIV-ECO 563-2016 on oenologist training…”
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La experiencia de la Asociación Pro-Derechos Humanos de Andalucía en centros de secundaria y bachillerato. El valor de la participación de las entidades sociales en los centros educativos by Serván Melero, Cristina

“…El presente artículo analiza el potencial de la educación en derechos humanos para la mejora del bienestar de las sociedades y la reducción de la injusticia…”
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Engineered Protein Connectivity to Actin Mimics PDZ-dependent Recycling of G Protein-coupled Receptors but Not Its Regulation by Hrs by Lauffer, Benjamin E.L., Chen, Stanford, Melero, Cristina, Kortemme, Tanja, von Zastrow, Mark, Vargas, Gabriel A.

“…Many G protein-coupled receptors (GPCRs) recycle after agonist-induced endocytosis by a sequence-dependent mechanism, which is distinct from default membrane…”
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Experiencia de doce médicos recién graduados al frente de un hotel sanitarizado durante la crisis COVID-19 by Bellas Fernández, Lucía, Melero Pérez, Cristina, Villares López, Alejandro, Huerga López, Cristina, Hernando Jiménez, Inés, Montero Ruiz, Eduardo

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The experience of twelve junior doctors working at a sanitized hotel during COVID-19 crisis by Bellas Fernández, Lucía, Melero Pérez, Cristina, Villares López, Alejandro, Huerga López, Cristina, Hernando Jiménez, Inés, Montero Ruiz, Eduardo

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Drosophila Short stop as a paradigm for the role and regulation of spectraplakins by Voelzmann, André, Liew, Yu-Ting, Qu, Yue, Hahn, Ines, Melero, Cristina, Sánchez-Soriano, Natalia, Prokop, Andreas

“…Spectraplakins are evolutionarily well conserved cytoskeletal linker molecules that are true members of three protein families: plakins, spectrins and…”
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Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux by Franco, María Luisa, Melero, Cristina, Sarasola, Esther, Acebo, Paloma, Luque, Alfonso, Calatayud-Baselga, Isabel, García-Barcina, María, Vilar, Marçal

“…Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder characterized by insensitivity to noxious stimuli and variable…”
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Vinculin is required for neuronal mechanosensing but not for axon outgrowth by Wang, De-Yao, Melero, Cristina, Albaraky, Ashwaq, Atherton, Paul, Jansen, Karin A., Dimitracopoulos, Andrea, Dajas-Bailador, Federico, Reid, Adam, Franze, Kristian, Ballestrem, Christoph

“…Integrin receptors are transmembrane proteins that bind to the extracellular matrix (ECM). In most animal cell types integrins cluster together with adaptor…”
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The Role of Integrin Adhesions in Axon Growth by Melero, Cristina

“…Axons are the slender cable-like extensions of neurons wiring the nervous system. They initially grow guided towards the correct destinations by motile devices…”
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La tradición de los Movimientos de Renovación Pedagógica en los Comunes Educativos. Un estudio de casos by Serván-Melero, Cristina, Beatriz, Gallego Noche, Lucía, Del Moral-Espín

“…Este artículo propone articular las relaciones entre la propuesta de los comunes educativos (CE) y los planteamientos de los Movimientos de Renovación…”
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Abstract 602: 23ME-00610 is a first-in-class monoclonal antibody that targets the CD200R1 immune checkpoint to enhance T cell-mediated antitumor activity by Fenaux, Jill, Huang, Yao-ming, Melero, Cristina, Chung, Wei-Jen, Lee, Suk, Ayupova, Dina, Poggio, Mauro, Glatt, Dylan, Yi, Zuoan, Lay, Cecilia, Schmidt, Maike, Majeed, Sophia R., Fuh, Germaine, Chen, Alice, Kumar, Sushil

“…In the 23andMe genetic database, associations were observed for CD200R1 variants and autoimmune and cancer traits with opposing directionality. These data…”
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La tradición de los Movimientos de Renovación Pedagógica en los Comunes Educativos: un estudio de casos by Serván Melero, Cristina, Gallego Noche, María Beatriz, Moral-Espín, Lucía del

“…本文拟阐明教育公地（EC）提案与 "教学革新运动"（MRP）方法之间的关系。教育公地是一种基于公地的理论-实践方法（Ostrom, 1990; Laval and Dardot,…”
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