Search Results - "Mele, A."
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Quantification and isotopic characterization of benzene polycarboxylic acids (BPCA)-derived black carbon in deep oceanic sediments: Towards assessing pyrogenic inputs from marine sources
Published in Organic geochemistry (01-07-2024)“…•A reproducible BPCA quantification procedure for deep-sea sediments.•Black carbon derived BPCA exhibit a notable prevalence in marine sediments.•Using BPCA…”
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Culturally responsive approaches to health promotion for Native Hawaiians and Pacific Islanders
Published in Annals of human biology (03-04-2018)“…Context: Obesity, diabetes and cardiovascular disease (CVD) have reached epidemic proportions among Native Hawaiians/Pacific Islanders (NHPI). Culturally…”
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Targeting MYC dependence in cancer by inhibiting BET bromodomains
Published in Proceedings of the National Academy of Sciences - PNAS (04-10-2011)“…The MYC transcription factor is a master regulator of diverse cellular functions and has been long considered a compelling therapeutic target because of its…”
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4
Quantitative Link Between Sedimentary Chlorin and Sea‐Surface Chlorophyll‐a
Published in Journal of geophysical research. Biogeosciences (01-05-2022)“…Primary productivity in the ocean plays a major role in the global carbon cycle. To estimate its changes through geological time, different sedimentary proxies…”
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BET bromodomain inhibition suppresses TH17-mediated pathology
Published in The Journal of experimental medicine (21-10-2013)“…Interleukin (IL) 17-producing T helper (T(H)17) cells have been selected through evolution for their ability to control fungal and bacterial infections. It is…”
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Nature-based and bioinspired solutions for coastal protection: an overview among key ecosystems and a promising pathway for new functional and sustainable designs
Published in ICES journal of marine science (29-06-2023)“…Abstract Coastal erosion is occurring at a faster rate than in the past. The adverse impacts are not negligible at environmental, economic, and socio-cultural…”
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Growing from Our Roots: Strategies for Developing Culturally Grounded Health Promotion Interventions in American Indian, Alaska Native, and Native Hawaiian Communities
Published in Prevention science (01-01-2020)“…Given the paucity of empirically based health promotion interventions designed by and for American Indian, Alaska Native, and Native Hawaiian (i.e., Native)…”
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Fast quantitative analysis of n-alkanes, PAHs and alkenones in sediments
Published in Organic geochemistry (01-09-2022)“…•Selective pressurized liquid extraction of organic biomarkers for paleoclimatology.•Fast and reproducible determination of alkenones, n-alkanes, and PAHs.•The…”
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Time-transgressive North Atlantic productivity changes upon Northern Hemisphere glaciation
Published in Paleoceanography (01-12-2013)“…Marine biological export productivity declined in high‐latitude regions in the North Pacific and Southern Ocean 2.7 million years ago, in parallel with the…”
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Offline ventral subiculum-ventral striatum serial communication is required for spatial memory consolidation
Published in Nature communications (16-12-2019)“…The hippocampal formation is considered essential for spatial navigation. In particular, subicular projections have been suggested to carry spatial information…”
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Short-Term Memory Deficit Associates with miR-153-3p Upregulation in the Hippocampus of Middle-Aged Mice
Published in Molecular neurobiology (01-05-2024)“…The early stages of ageing are a critical time window in which the ability to detect and identify precocious molecular and cognitive markers can make the…”
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The Next Generation of Pattern Recognition Receptor Agonists: Improving Response Rates in Cancer Immunotherapy
Published in Current medicinal chemistry (01-01-2020)“…The recent success of checkpoint blocking antibodies has sparked a revolution in cancer immunotherapy. Checkpoint inhibition activates the adaptive immune…”
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Cytotoxicity of corrosion products of degradable Fe-based stents: relevance of pH and insoluble products
Published in Colloids and surfaces, B, Biointerfaces (01-04-2015)“…Fe-based biodegradable metallic materials (Fe-BMMs) have been proposed for cardiovascular applications and are expected to disappear via corrosion after an…”
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Is there any difference in the biological impact of soluble and insoluble degradation products of iron-containing biomaterials?
Published in Colloids and surfaces, B, Biointerfaces (01-12-2017)“…[Display omitted] •Biodegradation of Fe-based materials involves both soluble and insoluble Fe species.•The effect of Fe-particles (Fe0p) and Fe0 ring on the…”
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Spontaneous adsorption of silver nanoparticles on Ti/TiO2 surfaces. Antibacterial effect on Pseudomonas aeruginosa
Published in Journal of colloid and interface science (15-10-2010)“…Titanium is a corrosion-resistant and biocompatible material widely used in medical and dental implants. Titanium surfaces, however, are prone to bacterial…”
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Smart Approach To Evaluate Drug Diffusivity in Injectable Agar−Carbomer Hydrogels for Drug Delivery
Published in The journal of physical chemistry. B (24-03-2011)“…Hydrogels are commonly studied for tissue engineering applications and controlled drug delivery. In order to evaluate their reliability as scaffolds and…”
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Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity
Published in Journal for immunotherapy of cancer (01-07-2020)“…Accumulation of extracellular adenosine within the microenvironment is a strategy exploited by tumors to escape detection by the immune system. Adenosine…”
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Late Glacial–Holocene climate variability at the south-eastern margin of the Aegean Sea
Published in Marine geology (15-10-2009)“…New micropaleontological, palynological, and geochemical results from a relatively shallow (∼ 500 m) sediment core (NS-14) in the south-eastern Aegean Sea…”
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Different Impact of Suspended Al2O3 Nanoparticles on Microbial Communities: Formation of 2D-Networks (Without Humic Acids) or 3D-Colonies (With Humic Acids)
Published in Microbial ecology (01-01-2023)“…The use of metal-based and, particularly, Al 2 O 3 nanoparticles (Al 2 O 3 -NP) for diverse purposes is exponentially growing. However, the growth of such…”
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A reduced basis approach to plasma equilibrium reconstruction in tokamaks
Published in Fusion engineering and design (01-05-2020)“…•A fast, data-driven algorithm for plasma equilibrium reconstruction based on PCA.•Application to the ITER case.•Analysis of the performance, improvement of…”
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