Search Results - "Meldrum, Deirdre R."

A Highly Selective Mitochondria-Targeting Fluorescent K+ Sensor by Kong, Xiangxing, Su, Fengyu, Zhang, Liqiang, Yaron, Jordan, Lee, Fred, Shi, Zhengwei, Tian, Yanqing, Meldrum, Deirdre R.

“…Regulation of intracellular potassium (K+) concentration plays a key role in metabolic processes. So far, only a few intracellular K+ sensors have been…”
Get full text

A New Highly Selective Fluorescent K+ Sensor by Zhou, Xianfeng, Su, Fengyu, Tian, Yanqing, Youngbull, Cody, Johnson, Roger H, Meldrum, Deirdre R

“…We describe the synthesis, properties, and application of a new fluorescent potassium chemosensor, KS2, for K+ sensing and imaging in live cells. By virtue of…”
Get full text

Application of synthetic biology in cyanobacteria and algae by Wang, Bo, Wang, Jiangxin, Zhang, Weiwen, Meldrum, Deirdre R

“…Cyanobacteria and algae are becoming increasingly attractive cell factories for producing renewable biofuels and chemicals due to their ability to capture…”
Get full text

Engineering cyanobacteria for photosynthetic production of 3-hydroxybutyrate directly from CO2 by Wang, Bo, Pugh, Shawn, Nielsen, David R., Zhang, Weiwen, Meldrum, Deirdre R.

“…(S)- and (R)-3-hydroxybutyrate (3HB) are precursors to synthesize the biodegradable plastics polyhydroxyalkanoates (PHAs) and many fine chemicals. To date,…”
Get full text

A simple non-perturbing cell migration assay insensitive to proliferation effects by Glenn, Honor L., Messner, Jacob, Meldrum, Deirdre R.

“…Migration is a fundamental cellular behavior that plays an indispensable role in development and homeostasis, but can also contribute to pathology such as…”
Get full text

Thin PDMS films using long spin times or tert-butyl alcohol as a solvent by Koschwanez, John H, Carlson, Robert H, Meldrum, Deirdre R

“…Thin polydimethylsiloxane (PDMS) films are frequently used in "lab on a chip" devices as flexible membranes. The common solvent used to dilute the PDMS for…”
Get full text

RT-qPCR based quantitative analysis of gene expression in single bacterial cells by Gao, Weimin, Zhang, Weiwen, Meldrum, Deirdre R.

“…Recent evidence suggests that cell-to-cell difference at the gene expression level is an order of magnitude greater than previously thought even for isogenic…”
Get full text

Triazacryptand-based fluorescent sensors for extracellular and intracellular K+ sensing by Zhou, Xianfeng, Su, Fengyu, Gao, Weimin, Tian, Yanqing, Youngbull, Cody, Johnson, Roger H, Meldrum, Deirdre R

“…Abstract A 4-amino-naphthalimide derived fluorophore with a triazacryptand moiety ligand was synthesized as a potassium ion (K+ ) sensor (KS1). This sensor is…”
Get full text

A versatile method for dynamically controlled patterning of small populations of epithelial cells on substrates via non-contact piezoelectric inkjet printing by Lee, Kristen B, Kelbauskas, Laimonas, Brunner, Alan, Meldrum, Deirdre R

“…Intercellular interactions play a central role at the tissue and whole organism level modulating key cellular functions in normal and disease states. Studies…”
Get full text

Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations by Nandakumar, Vivek, Kelbauskas, Laimonas, Hernandez, Kathryn F, Lintecum, Kelly M, Senechal, Patti, Bussey, Kimberly J, Davies, Paul C W, Johnson, Roger H, Meldrum, Deirdre R

“…Grading schemes for breast cancer diagnosis are predominantly based on pathologists' qualitative assessment of altered nuclear structure from 2D brightfield…”
Get full text

Dually fluorescent core-shell microgels for ratiometric imaging in live antigen-presenting cells by Zhou, Xianfeng, Su, Fengyu, Tian, Yanqing, Meldrum, Deirdre R

“…Core-shell microgels containing sensors/dyes in a matrix were fabricated by two-stage free radical precipitation polymerization method for ratiometric…”
Get full text

Laser-fabricated cell patterning stencil for single cell analysis by Messner, Jacob J, Glenn, Honor L, Meldrum, Deirdre R

“…Precise spatial positioning and isolation of mammalian cells is a critical component of many single cell experimental methods and biological engineering…”
Get full text

A polymer-based ratiometric intracellular glucose sensor by Zhang, Liqiang, Su, Fengyu, Buizer, Sean, Kong, Xiangxing, Lee, Fred, Day, Kevin, Tian, Yanqing, Meldrum, Deirdre R

“…The glucose metabolism level reflects cell proliferative status. A polymeric glucose ratiometric sensor comprising poly(N-(2-hydroxypropyl)methacrylamide)…”
Get more information

Nanostructured oxygen sensor--using micelles to incorporate a hydrophobic platinum porphyrin by Su, Fengyu, Alam, Ruhaniyah, Mei, Qian, Tian, Yanqing, Youngbull, Cody, Johnson, Roger H, Meldrum, Deirdre R

“…Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from…”
Get full text

Integrated metagenomic and metatranscriptomic analyses of microbial communities in the meso- and bathypelagic realm of north pacific ocean by Wu, Jieying, Gao, Weimin, Johnson, Roger H, Zhang, Weiwen, Meldrum, Deirdre R

“…Although emerging evidence indicates that deep-sea water contains an untapped reservoir of high metabolic and genetic diversity, this realm has not been…”
Get full text

Platinum (II) porphyrin-containing thermoresponsive poly( N-isopropylacrylamide) copolymer as fluorescence dual oxygen and temperature sensor by Zhou, Xianfeng, Su, Fengyu, Tian, Yanqing, Johnson, Roger H., Meldrum, Deirdre R.

“…A random copolymer, poly(NIPAAm- co-PtPorphyrin), consisting of N-isopropylacrylamide (NIPAAm) and platinum (II) porphyrin units, behaves as an optical dual…”
Get full text

Monitoring the Single-Cell Stress Response of the Diatom Thalassiosira pseudonana by Quantitative Real-Time Reverse Transcription-PCR by XU SHI, WEIMIN GAO, CHAO, Shih-Hui, WEIWEN ZHANG, MELDRUM, Deirdre R

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Automated Selection and Placement of Single Cells Using Vision-Based Feedback Control by Anis, Yasser H, Holl, Mark R, Meldrum, Deirdre R

“…We present a robotic manipulation system for automated selection and transfer of individual living cells to analysis locations. We begin with a commonly used…”
Get full text

A platform for high-throughput bioenergy production phenotype characterization in single cells by Kelbauskas, Laimonas, Glenn, Honor, Anderson, Clifford, Messner, Jacob, Lee, Kristen B., Song, Ganquan, Houkal, Jeff, Su, Fengyu, Zhang, Liqiang, Tian, Yanqing, Wang, Hong, Bussey, Kimberly, Johnson, Roger H., Meldrum, Deirdre R.

“…Driven by an increasing number of studies demonstrating its relevance to a broad variety of disease states, the bioenergy production phenotype has been widely…”
Get full text

Single-cell analysis reveals early manifestation of cancerous phenotype in pre-malignant esophageal cells by Wang, Jiangxin, Shi, Xu, Johnson, Roger H, Kelbauskas, Laimonas, Zhang, Weiwen, Meldrum, Deirdre R

“…Cellular heterogeneity plays a pivotal role in a variety of functional processes in vivo including carcinogenesis. However, our knowledge about cell-to-cell…”
Get full text