Search Results - "Meldrum, C J"

An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus by Chow, E, Meldrum, CJ, Crooks, R, Macrae, F, Spigelman, AD, Scott, RJ

“…The genetic predisposition Peutz–Jeghers Syndrome (PJS) has been shown to be associated with mutations in the serine threonine kinase 11 (STK11) gene but only…”
Get full text

Hereditary non-polyposis colorectal cancer and the role of hPMS2 and hEXO1 mutations by Thompson, E, Meldrum, CJ, Crooks, R, McPhillips, M, Thomas, L, Spigelman, AD, Scott, RJ

“…Hereditary non‐polyposis colorectal cancer (HNPCC) is an autosomal dominant, inherited condition that is characterized primarily by the development of…”
Get full text

Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients by Scott, RJ, Crooks, R, Meldrum, CJ, Thomas, L, Smith, CJA, Mowat, D, McPhillips, M, Spigelman, AD

“…Peutz–Jeghers syndrome (PJS) is a rare cancer predisposition, which is characterized by the presence of hamartomatous polyposis and mucocutaneous pigmentation…”
Get full text

Hereditary Nonpolyposis Colorectal Cancer in 95 Families: Differences and Similarities between Mutation-Positive and Mutation-Negative Kindreds by Scott, Rodney J., McPhillips, Mary, Meldrum, Cliff J., Fitzgerald, Patrick E., Adams, Kirsten, Spigelman, Allan D., du Sart, Desiree, Tucker, Kathy, Kirk, Judy

“…Hereditary nonpolyposis colorectal cancer (HNPCC) describes the condition of a disparate group of families that have in common a predisposition to colorectal…”
Get full text

The -149C>T SNP within the [Delta]DNMT3B gene, is not associated with early disease onset in hereditary non-polyposis colorectal cancer by Reeves, SG, Mossman, D, Meldrum, CJ, Kurzawski, G, Suchy, J, Lubinski, J, Scott, RJ

“…Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited syndrome caused by germline mutations in mismatch repair (MMR) genes…”
Get full text

A Fibroblast Elongation Factor Purified from Colon Carcinoma Cells Shares Sequence Identity with TIMP-1 by Agrez, M.V., Meldrum, C.J., Sim, A.T.R., Aebersold, R.H., Clark, I.M., Cawston, T.E., Burns, G.F.

“…We have previously reported that human colon cancer cells secrete a factor(s) which induces elongation of colon fibroblasts in vitro. Isolation of this factor…”
Get full text

Biochemical isolation of a membrane microdomain from resting platelets highly enriched in the plasma membrane glycoprotein CD36 by Dorahy, D J, Lincz, L F, Meldrum, C J, Burns, G F

“…Here we describe the isolation and characterization of a Triton X-100-insoluble fraction isolated from lysates of platelets by flotation in sucrose gradients…”
Get full text

BRCA2 mutations in a population‐based series of patients with ocular melanoma by Scott, Rodney J., Vajdic, Claire M., Armstrong, Bruce K., Ainsworth, Christopher J., Meldrum, Cliff J., Aitken, Joanne F., Kricker, Anne

“…We studied the BRCA2 gene for germline mutations in 71 of 99 patients (72%) with ocular melanoma who were diagnosed consecutively in Australia in 1997 and…”
Get full text

CD36 Forms Covalently Associated Dimers and Multimers in Platelets and Transfected COS-7 Cells by Thorne, Rick F., Meldrum, Clifford J., Harris, Simon J., Dorahy, Douglas J., Shafren, Darren R., Berndt, Michael C., Burns, Gordon F., Gibson, Peter G.

“…CD36 is a transmembrane glycoprotein expressed on the surface of a number of cell types. The analysis of CD36 from platelets using immunoblotting, gel…”
Get full text

The −149C>T SNP within the ΔDNMT3B gene, is not associated with early disease onset in hereditary non-polyposis colorectal cancer by Reeves, S.G, Mossman, D, Meldrum, C.J, Kurzawski, G, Suchy, J, Lubinski, J, Scott, R.J

“…Abstract Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited syndrome caused by germline mutations in mismatch repair (MMR)…”
Get full text

The -149C>T SNP within the DeltaDNMT3B gene, is not associated with early disease onset in hereditary non-polyposis colorectal cancer by Reeves, S G, Mossman, D, Meldrum, C J, Kurzawski, G, Suchy, J, Lubinski, J, Scott, R J

“…Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited syndrome caused by germline mutations in mismatch repair (MMR) genes…”
Get full text

Abstract P2-07-05: Prevalence of germline BRCA1 and BRCA2 mutations in triple-negative breast cancer patients unselected for family history by Scott, RJ, Wong-Brown, M, Meldrum, CJ, Avery-Kiejda, K

“…Abstract Triple-negative breast cancer (TNBC) is a histological classification of a breast cancer subtype that is negative for the estrogen receptor (ER),…”
Get full text

Short Report: An updated mutation spectrum in an Australian series of PJS patients provides further evidence for only one gene locus by Chow, E, Meldrum, C J, Crooks, R, Macrae, F, Spigelman, AD, Scott, R J

“…Chow E, Meldrum CJ, Crooks R, Macrae F, Spigelman AD, Scott RJ. An updated mutation spectrum in an Australian series of PJS patients provides further evidence…”
Get full text

Phenotype-Genotype Correlations in a Series of Wolfram Syndrome Families by Smith, Casey J A, Crock, Patricia A, King, Bruce R, Meldrum, Cliff J, Scott, Rodney J

“…Phenotype-Genotype Correlations in a Series of Wolfram Syndrome Families Casey J.A. Smith , BSC 1 , Patricia A. Crock , MD 1 , Bruce R. King , MD 1 , Cliff J…”
Get full text

Direct integrin alpha v beta 6-ERK binding: implications for tumour growth by Ahmed, N, Niu, J, Dorahy, D J, Gu, Xinhua, Andrews, S, Meldrum, C J, Scott, R J, Baker, MS, Macreadie, I G, Agrez, M V

“…Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in vivo. Here we demonstrate a direct link between the…”
Get full text

Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations by Kairupan, Carla F., Meldrum, Cliff J., Crooks, Renee, Milward, Elizabeth A., Spigelman, Allan D., Burgess, Bronwyn, Groombridge, Claire, Kirk, Judy, Tucker, Kathy, Ward, Robyn, Williams, Rachel, Scott, Rodney J.

“…The MYH gene has recently been shown to be associated with a recessive form of colorectal adenomatous polyposis. Two common mutations in the MYH gene have been…”
Get full text

Response to De Vos et al

Get full text