Multiple sclerosis in South America: month of birth in different latitudes does not seem to interfere with the prevalence or progression of the disease

To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life. Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and di...

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Published in:	Arquivos de neuro-psiquiatria Vol. 71; no. 9A; pp. 573 - 579
Main Authors:	Fragoso, Yára Dadalti, Adoni, Tarso, Almeida, Sandra Maria Garcia de, Alves-Leon, Soniza Vieira, Arruda, Walter Oleschko, Barbagelata-Aguero, Fiorella, Brooks, Joseph Bruno Bidin, Carra, Adriana, Claudino, Rinaldo, Comini-Frota, Elizabeth Regina, Correa, Eber Castro, Damasceno, Alfredo, Damasceno, Benito Pereira, Díaz, Ethel Ciampi, Elliff, David George, Fiore, Ana Patrícia Peres, Franco, Clelia Maria Ribeiro, Giacomo, Maria Cristina Brandao, Gomes, Sidney, Gonçalves, Marcus Vinicius Magno, Grzesiuk, Anderson Kuntz, Inojosa, Jose Luiz, Kaimen-Maciel, Damacio Ramón, Lin, Katia, Lopes, Josiane, Lourenço, Gisele Alexandre, Martínez, Alejandra Diana, Melcon, Mario Oscar, Morales, Nívea de Macedo Oliveira, Morales, Rogério Rizo, Moreira, Marcos, Moreira, Shirlene Vianna, Oliveira, Celso Luis da Silva, Oliveira, Francisco Tomaz Menezes de, Ribeiro, João Batista, Ribeiro, Sonia Beatriz Felix, Rodríguez, Claudia Cárcamo, Russo, Liliana, Safanelli, Juliana, Shearer, Kirsty Deborah, Siquineli, Fabio, Vizcarra-Escobar, Darwin
Format:	Journal Article
Language:	English
Published:	Brazil Academia Brasileira de Neurologia - ABNEURO 01-09-2013 Academia Brasileira de Neurologia (ABNEURO)
Subjects:	Adult America do Sul Disease Progression Epidemiologic Methods esclerose multipla exposicao solar Female Humans Male Multiple Sclerosis - epidemiology Multiple Sclerosis - etiology NEUROSCIENCES Parturition PSYCHIATRY Seasons South America - epidemiology Topography, Medical South America South America sun exposure esclerose multipla multiple sclerosis exposicao solar America do Sul
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Summary:	To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life. Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression. Analysis of data from 1207 MS patients and 1207 control subjects did not show any significant variation in the month of birth regarding the prevalence of MS in four latitude bands (0-10; 11-20; 21-30; and 31-40 degrees). There was no relationship between the month of birth and the severity of disease in each latitude band. The results from this study show that MS patients born to mothers who were pregnant at different Southern latitudes do not follow the seasonal pattern observed at high Northern latitudes.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0004-282X 1678-4227 1678-4227 0004-282X
DOI:	10.1590/0004-282X20130098