Search Results - "Melchor, Stephanie J"
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Toxoplasma gondii infection triggers chronic cachexia and sustained commensal dysbiosis in mice
Published in PloS one (31-10-2018)“…Toxoplasma gondii is a protozoan parasite with a predation-mediated transmission cycle between rodents and felines. Intermediate hosts acquire Toxoplasma by…”
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Disease Tolerance in Toxoplasma Infection
Published in Frontiers in cellular and infection microbiology (06-06-2019)“…is a successful protozoan parasite that cycles between definitive felid hosts and a broad range of intermediate hosts, including rodents and humans. Within…”
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Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia
Published in Heliyon (01-07-2023)“…Cachexia is a life-threatening disease characterized by chronic, inflammatory muscle wasting and systemic metabolic impairment. Despite its high prevalence,…”
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IL-1R Regulates Disease Tolerance and Cachexia in Toxoplasma gondii Infection
Published in The Journal of immunology (1950) (15-06-2020)“…is an obligate intracellular parasite that establishes life-long infection in a wide range of hosts, including humans and rodents. To establish a chronic…”
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Tuft Cells: New Players in Colitis
Published in Trends in molecular medicine (01-11-2016)“…Abstract A recent surge of interest in tuft cells, which are chemosensory intestinal epithelial cells, has uncovered new functional roles for these cells in…”
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T. gondii infection induces IL-1R dependent chronic cachexia and perivascular fibrosis in the liver and skeletal muscle
Published in Scientific reports (24-09-2020)“…Cachexia is a progressive muscle wasting disease that contributes to death in a wide range of chronic diseases. Currently, the cachexia field lacks animal…”
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Acute Lymph Node Slices Are a Functional Model System to Study Immunity Ex Vivo
Published in ACS pharmacology & translational science (12-02-2021)“…The lymph node is a highly organized and dynamic structure that is critical for facilitating the intercellular interactions that constitute adaptive immunity…”
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IL-1R regulates disease tolerance and cachexia in T. gondii infection
Published in The Journal of immunology (1950) (29-04-2020)“…T. gondii is an obligate intracellular parasite that establishes life-long infection in a wide range of hosts, including humans and rodents. To establish a…”
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