Search Results - "Melcher, S E"

Surgical correction of the medial rotation contracture in obstetric brachial plexus palsy by Nath, R K, Lyons, A B, Melcher, S E, Paizi, M

“…The medial rotation contracture caused by weak external rotation secondary to obstetric brachial plexus injury leads to deformation of the bones of the…”
Get full text

Thermodynamics of the interactions of Lac repressor with variants of the symmetric Lac operator: effects of converting a consensus site to a non-specific site by Frank, Diane E., Saecker, Ruth M., Bond, Jeffrey P., Capp, Michael W., Tsodikov, Oleg V., Melcher, Sonya E., Levandoski, Mark M., Record, M.Thomas

“…What are the thermodynamic consequences of the stepwise conversion of a highly specific (consensus) protein-DNA interface to one that is non-specific? How do…”
Get full text

Wrapping of flanking non-operator DNA in lac repressor-operator complexes: implications for DNA looping by Tsodikov, O V, Saecker, R M, Melcher, S E, Levandoski, M M, Frank, D E, Capp, M W, Record, Jr, M T

“…In our studies of lac repressor tetramer (T)-lac operator (O) interactions, we observed that the presence of extended regions of non-operator DNA flanking a…”
Get full text

Compensating effects of opposing changes in putrescine (2+) and K+ concentrations on lac repressor-lac operator binding: in vitro thermodynamic analysis and in vivo relevance by Capp, M W, Cayley, D S, Zhang, W, Guttman, H J, Melcher, S E, Saecker, R M, Anderson, C F, Record, Jr, M T

“…Ion concentrations (K+, Glu-) in the cytoplasm of growing Escherichia coli cells increase strongly with increases in the osmolarity of a defined growth medium…”
Get full text

The kink-turn motif in RNA is dimorphic, and metal ion-dependent by Goody, Terry A, Melcher, Sonya E, Norman, David G, Lilley, David M J

“…The kink-turn (K-turn) is a new motif in RNA structure that was identified by examination of the crystal structures of the ribosome. We examined the structural…”
Get full text

Induced fit of RNA on binding the L7Ae protein to the kink-turn motif by Turner, Ben, Melcher, Sonya E, Wilson, Timothy J, Norman, David G, Lilley, David M J

“…The kink-turn is a widespread motif in RNA consisting of a three-nucleotide bulge flanked on one side by consecutive A3G mismatches. Important examples are…”
Get full text

The dynamic nature of the four-way junction of the hepatitis C virus IRES by Melcher, Sonya E, Wilson, Timothy J, Lilley, David M J

“…Translation is initiated within the RNA of the hepatitis C virus at the internal ribosome entry site (IRES). The IRES is a 341-nucleotide element that contains…”
Get full text

Cooperative and anticooperative effects in binding of the first and second plasmid Osym operators to a LacI tetramer: evidence for contributions of non-operator DNA binding by wrapping and looping by Levandoski, M M, Tsodikov, O V, Frank, D E, Melcher, S E, Saecker, R M, Record, Jr, M T

“…The interaction of lac operator DNA with lac repressor (LacI) is a classic example of a genetic regulatory switch. To dissect the role of stoichiometry,…”
Get full text

Cooperative and anticooperative effects in binding of the first and second plasmid O super(sym) operators to a LacI tetramer: Evidence for contributions of non-operator DNA binding by wrapping and looping by Levandoski, M M, Tsodikov, O V, Frank, DE, Melcher, SE, Saecker, R M, Record, MT Jr

“…The interaction of lac operator DNA with lac repressor (LacI) is a classic example of a genetic regulatory switch. To dissect the role of stoichiometry,…”
Get full text

Compensating effects of opposing changes in putrescine (2+) and K super(+) concentrations on lac repressor-lac operator binding: In vitro thermodynamic analysis and in vivo relevance by Capp, M W, Cayley, D S, Zhang, W, Guttman, HJ, Melcher, SE, Saecker, R M, Anderson, C F, Record, MT Jr

“…Ion concentrations (K super(+), Glu super(-)) in the cytoplasm of growing Escherichia coli cells increase strongly with increases in the osmolarity of a…”
Get full text