Search Results - "Melarkode Vattekatte, Akhila"

Molecular and Structural Basis of Cross-Reactivity in M. tuberculosis Toxin-Antitoxin Systems by Tandon, Himani, Melarkode Vattekatte, Akhila, Srinivasan, Narayanaswamy, Sandhya, Sankaran

“…genome encodes over 80 toxin-antitoxin (TA) systems. While each toxin interacts with its cognate antitoxin, the abundance of TA systems presents an opportunity…”
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Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction by Melarkode Vattekatte, Akhila, Shinada, Nicolas Ken, Narwani, Tarun J, Noël, Floriane, Bertrand, Olivier, Meyniel, Jean-Philippe, Malpertuy, Alain, Gelly, Jean-Christophe, Cadet, Frédéric, de Brevern, Alexandre G

“…Antigen binding by antibodies requires precise orientation of the complementarity- determining region (CDR) loops in the variable domain to establish the…”
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Data set of intrinsically disordered proteins analysed at a local protein conformation level by Melarkode Vattekatte, Akhila, Narwani, Tarun Jairaj, Floch, Aline, Maljković, Mirjana, Bisoo, Soubika, Shinada, Nicolas K., Kranjc, Agata, Gelly, Jean-Christophe, Srinivasan, Narayanaswamy, Mitić, Nenad, de Brevern, Alexandre G.

“…Intrinsic Disorder Proteins (IDPs) have become a hot topic since their characterisation in the 90s. The data presented in this article are related to our…”
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General Trends of the Camelidae Antibody VHHs Domain Dynamics by Vattekatte, Akhila Melarkode, Diharce, Julien, Rebehmed, Joseph, Cadet, Frédéric, Gardebien, Fabrice, Etchebest, Catherine, de Brevern, Alexandre G.

“…Conformational flexibility plays an essential role in antibodies’ functional and structural stability. They facilitate and determine the strength of…”
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Insights into Comparative Modeling of VHH Domains by Vattekatte, Akhila Melarkode, Cadet, Frédéric, Gelly, Jean-Christophe, de Brevern, Alexandre G.

“…In the particular case of the Camelidae family, immunoglobulin proteins have evolved into a unique and more simplified architecture with only heavy chains. The…”
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VHH Structural Modelling Approaches: A Critical Review by Vishwakarma, Poonam, Vattekatte, Akhila Melarkode, Shinada, Nicolas, Diharce, Julien, Martins, Carla, Cadet, Frédéric, Gardebien, Fabrice, Etchebest, Catherine, Nadaradjane, Aravindan Arun, de Brevern, Alexandre G.

“…VHH, i.e., VH domains of camelid single-chain antibodies, are very promising therapeutic agents due to their significant physicochemical advantages compared to…”
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Recent advances on polyproline II by Narwani, Tarun Jairaj, Santuz, Hubert, Shinada, Nicolas, Melarkode Vattekatte, Akhila, Ghouzam, Yassine, Srinivasan, Narayanasamy, Gelly, Jean-Christophe, de Brevern, Alexandre G.

“…About half of the globular proteins are composed of regular secondary structures, α-helices, and β-sheets, while the rest are constituted of irregular…”
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Discrete analyses of protein dynamics by Narwani, Tarun Jairaj, Craveur, Pierrick, Shinada, Nicolas K., Floch, Aline, Santuz, Hubert, Vattekatte, Akhila Melarkode, Srinivasan, Narayanaswamy, Rebehmed, Joseph, Gelly, Jean-Christophe, Etchebest, Catherine, de Brevern, Alexandre G.

“…Protein structures are highly dynamic macromolecules. This dynamics is often analysed through experimental and/or computational methods only for an isolated or…”
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General Trends of the ICamelidae/I Antibody V[sub.H]Hs Domain Dynamics by Vattekatte, Akhila Melarkode, Diharce, Julien, Rebehmed, Joseph, Cadet, Frédéric, Gardebien, Fabrice, Etchebest, Catherine, de Brevern, Alexandre G

“…Conformational flexibility plays an essential role in antibodies' functional and structural stability. They facilitate and determine the strength of…”
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A structural entropy index to analyse local conformations in intrinsically disordered proteins: IDP PBs by Melarkode Vattekatte, Akhila, Narwani, Tarun Jairaj, Floch, Aline, Maljković, Mirjana, Bisoo, Soubika, Shinada, Nicolas K, Kranjc, Agata, Gelly, Jean-Christophe, Srinivasan, Narayanaswamy, Mitić, Nenad, de Brevern, Alexandre

“…Sequence – structure – function paradigm has been revolutionized by the discovery of disordered regions and disordered proteins more than two decades ago…”
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A structural entropy index to analyse local conformations in intrinsically disordered proteins by Akhila, Melarkode Vattekatte, Narwani, Tarun Jairaj, Floch, Aline, Maljković, Mirjana, Bisoo, Soubika, Shinada, Nicolas K., Kranjc, Agata, Gelly, Jean-Christophe, Srinivasan, Narayanaswamy, Mitić, Nenad, de Brevern, Alexandre G.

“…[Display omitted] •Analyses of ensemble of Intrinsic Disorder Proteins.•Use of a protein structural alphabet to analyze the IDP ensemble.•Local protein…”
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General Trends of the Camelidae Antibody V H Hs Domain Dynamics by Vattekatte, Akhila Melarkode, Diharce, Julien, Rebehmed, Joseph, Cadet, Frédéric, Gardebien, Fabrice, Etchebest, Catherine, de Brevern, Alexandre G

“…Conformational flexibility plays an essential role in antibodies' functional and structural stability. They facilitate and determine the strength of…”
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V H H Structural Modelling Approaches: A Critical Review by Vishwakarma, Poonam, Vattekatte, Akhila Melarkode, Shinada, Nicolas, Diharce, Julien, Martins, Carla, Cadet, Frédéric, Gardebien, Fabrice, Etchebest, Catherine, Nadaradjane, Aravindan Arun, de Brevern, Alexandre G

“…V H, i.e., VH domains of camelid single-chain antibodies, are very promising therapeutic agents due to their significant physicochemical advantages compared to…”
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Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction: Sequence-structure characteristics of VHH domains by Melarkode Vattekatte, Akhila, Shinada, Nicolas Ken, Narwani, Tarun J, Noël, Floriane, Bertrand, Olivier, Meyniel, Jean-Philippe, Malpertuy, Alain, Gelly, Jean-Christophe, Cadet, Frédéric, de Brevern, Alexandre

“…Antigen binding by antibodies requires precise orientation of the complementarity- determining region (CDR) loops in the variable domain to establish the…”
Get full text