Search Results - "Melamed, Sahar"

New sequencing methodologies reveal interplay between multiple RNA-binding proteins and their RNAs by Melamed, Sahar

“…It is now established that base-pairing regulatory RNAs are key players in post-transcriptional regulatory networks where they affect the translation and/or…”
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RNA-RNA Interactomes of ProQ and Hfq Reveal Overlapping and Competing Roles by Melamed, Sahar, Adams, Philip P., Zhang, Aixia, Zhang, Hongen, Storz, Gisela

“…Base pairing RNAs modulate gene expression in all studied organisms. In many bacteria, the base pairing between most small regulatory RNAs (sRNAs) and their…”
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Global Mapping of Small RNA-Target Interactions in Bacteria by Melamed, Sahar, Peer, Asaf, Faigenbaum-Romm, Raya, Gatt, Yair E., Reiss, Niv, Bar, Amir, Altuvia, Yael, Argaman, Liron, Margalit, Hanah

“…Small RNAs (sRNAs) associated with the RNA chaperon protein Hfq are key posttranscriptional regulators of gene expression in bacteria. Deciphering the…”
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σ28-dependent small RNA regulation of flagella biosynthesis by Melamed, Sahar, Zhang, Aixia, Jarnik, Michal, Mills, Joshua, Silverman, Aviezer, Zhang, Hongen, Storz, Gisela

“…Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive…”
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An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae by Huber, Michaela, Lippegaus, Anne, Melamed, Sahar, Siemers, Malte, Wucher, Benjamin R., Hoyos, Mona, Nadell, Carey, Storz, Gisela, Papenfort, Kai

“…Small regulatory RNAs (sRNAs) acting in concert with the RNA chaperone Hfq are prevalent in many bacteria and typically act by base-pairing with multiple…”
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Online Monitoring of Water Toxicity by Use of Bioluminescent Reporter Bacterial Biochips by Elad, Tal, Almog, Ronen, Yagur-Kroll, Sharon, Levkov, Klimentiy, Melamed, Sahar, Shacham-Diamand, Yosi, Belkin, Shimshon

“…We describe a flow-through biosensor for online continuous water toxicity monitoring. At the heart of the device are disposable modular biochips incorporating…”
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Introducing new group leaders: Sahar Melamed

“…Sahar Melamed spoke with Molecular Cell about his interdisciplinary group at the Hebrew University of Jerusalem, which applies experimental and computational…”
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Small RNAs, Large Networks: Posttranscriptional Regulons in Gram-Negative Bacteria by Papenfort, Kai, Melamed, Sahar

“…Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates…”
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Division of Infectious Diseases, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115 by Gebhardt, Michael J, Farland, Elizabeth A, Basu, Pallabi, Macareno, Keven, Melamed, Sahar, Dove, Simon L

“…The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the base pairing between small RNAs (sRNAs) and their cognate mRNA…”
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Microbial sensor cell arrays by Melamed, Sahar, Elad, Tal, Belkin, Shimshon

“…Highlights ► We describe the concept of whole cell arrays, the next step in biosensor technology. ► Live sensor cell arrays sense and report multiple…”
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Mapping the small RNA interactome in bacteria using RIL-seq by Melamed, Sahar, Faigenbaum-Romm, Raya, Peer, Asaf, Reiss, Niv, Shechter, Omer, Bar, Amir, Altuvia, Yael, Argaman, Liron, Margalit, Hanah

“…This protocol describes an experimental–computational methodology for mapping the small RNA interactome in bacteria. Small RNAs (sRNAs) are major…”
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Hfq-licensed RNA-RNA interactome in Pseudomonas aeruginosa reveals a keystone sRNA by Gebhardt, Michael J, Farland, Elizabeth A, Basu, Pallabi, Macareno, Keven, Melamed, Sahar, Dove, Simon L

“…The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the base pairing between small RNAs (sRNAs) and their cognate mRNA…”
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σ28-dependent small RNA regulation of flagella biosynthesis by Melamed, Sahar, Zhang, Aixia, Jarnik, Michal, Mills, Joshua, Silverman, Aviezer, Zhang, Hongen, Storz, Gisela

“…Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive…”
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Improved detection of antibiotic compounds by bacterial reporter strains achieved by manipulations of membrane permeability and efflux capacity by Melamed, Sahar, Naftaly, Sharon, Belkin, Shimshon

“…The occurrence of pharmaceuticals, including antibacterial compounds, in the environment has been acknowledged as an emerging and troubling issue in…”
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σ 28 -dependent small RNA regulation of flagella biosynthesis by Melamed, Sahar, Zhang, Aixia, Jarnik, Michal, Mills, Joshua, Silverman, Aviezer, Zhang, Hongen, Storz, Gisela

“…Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive…”
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Biological insights from RIL-seq in bacteria by Silverman, Aviezer, Melamed, Sahar

“…Methods Mol Biol 2866, 189-206 (2025) Bacteria reside in constantly changing environments and require rapid and precise adjustments of gene expression to…”
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A printed nanolitre-scale bacterial sensor array by Melamed, Sahar, Ceriotti, Laura, Weigel, Wilfried, Rossi, François, Colpo, Pascal, Belkin, Shimshon

“…The last decade has witnessed a significant increase in interest in whole-cell biosensors for diverse applications, as well as a rapid and continuous expansion…”
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Whole-cell biochips for bio-sensing: integration of live cells and inanimate surfaces by Ben-Yoav, Hadar, Melamed, Sahar, Freeman, Amihay, Shacham-Diamand, Yosi, Belkin, Shimshon

“…Recent advances in the convergence of the biological, chemical, physical, and engineering sciences have opened new avenues of research into the interfacing of…”
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A bacterial bioreporter panel to assay the cytotoxicity of atmospheric particulate matter by Kessler, Nivi, Schauer, James J., Yagur-Kroll, Sharon, Melamed, Sahar, Tirosh, Ofir, Belkin, Shimshon, Erel, Yigal

“…Numerous studies have demonstrated that elevated concentrations of suspended atmospheric particulate matter (PM) are associated with adverse health effects. In…”
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A bacterial reporter panel for the detection and classification of antibiotic substances by Melamed, Sahar, Lalush, Chaim, Elad, Tal, Yagur‐Kroll, Sharon, Belkin, Shimshon, Pedahzur, Rami

“…Summary The ever‐growing use of pharmaceutical compounds, including antibacterial substances, poses a substantial pollution load on the environment. Such…”
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