Search Results - "Mela, Marta"
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Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice
Published in Scientific reports (09-02-2016)“…Activation of the AKT/mTOR cascade and overexpression of c-Met have been implicated in the development of human hepatocellular carcinoma (HCC). To elucidate…”
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Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans
Published in Journal of hepatology (01-02-2016)“…Graphical abstract…”
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Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma
Published in Medicina (Kaunas, Lithuania) (18-12-2019)“…: Intrahepatic cholangiocarcinoma (iCCA) is a pernicious tumor characterized by a dismal outcome and scarce therapeutic options. To substantially improve the…”
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Journal Article