Search Results - "Mekki, Q. A."

Effect of Low- and High-Fat Meals on Tacrolimus Absorption following 5 mg Single Oral Doses to Healthy Human Subjects by Bekersky, Ihor, Dressler, Dawna, Mekki, Qais A.

“…Tacrolimus (FK506, Prograf®) is a macrolide lactone antibiotic widely used by the oral route for the prophylaxis of organ rejection in patients who have…”
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Pharmacokinetics of tacrolimus in liver transplant patients by Jusko, W J, Piekoszewski, W, Klintmalm, G B, Shaefer, M S, Hebert, M F, Piergies, A A, Lee, C C, Schechter, P, Mekki, Q A

“…To characterize the pharmacokinetics of the immunosuppressive agent tacrolimus (FK 506) in liver transplant patients. Patients (n = 16) were assessed during…”
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Dose linearity after oral administration of tacrolimus 1-mg capsules at doses of 3, 7, and 10 mg by Bekersky, Ihor, Dressler, Dawna, Mekki, Qais A.

“…Tacrolimus is an immunosuppressant drug used for the prophylaxis of organ rejection in patients who receive allogenic liver or kidney transplants. This study…”
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Stimulation of dopamine receptors (type 2) lowers human intraocular pressure by Mekki, Q A, Turner, P

“…The interaction between bromocriptine and metoclopramide on intraocular pressure (IOP), pupil diameter, and other parameters were studied in healthy…”
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Comparative Tacrolimus Pharmacokinetics: Normal versus Mildly Hepatically Impaired Subjects by Bekersky, Ihor, Dressler, Dawna, Alak, Ala, Boswell, Gary W., Mekki, Qais A.

“…Tacrolimus (FK506, Prograf®), marketed for the prophylaxis of organ rejection following allogenic liver or kidney transplantation, is virtually completely…”
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Dopamine-2 receptor blockade does not affect the ocular hypotensive action of timolol by Mekki, Q A, Turner, P

“…We have shown that metoclopramide, a dopamine-2 antagonist, failed to antagonise the ocular hypotensive action of timolol. The practical implication of…”
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Effect of atenolol on red blood cell deformability by SINAWI LUBNA, A.-H. A, SOWEMIMO-COKER, S. O, MEKKI, Q. A, TURNER, P

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Effect of a hydantoin prostaglandin analogue, BW245C, during oral dosing in man by Al-Sinawi, L A, Mekki, Q A, Hassan, S, Hedges, A, Burke, C, Moody, S G, O'Grady, J

“…Following an open pilot study, the effects of repeated oral doses of BW245C, a hydantoin prostaglandin analogue, were studied in man. Six healthy volunteers…”
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Bromocriptine lowers intraocular pressure without affecting blood pressure by Mekki, Q A, Hassan, S M, Turner, P

“…Oral bromocriptine (1.25 mg) was given to 8 healthy volunteers in a double-blind placebo controlled cross-over study. 3 and 4 h after taking the tablet there…”
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Bromocriptine eyedrops lower intraocular pressure without affecting prolactin levels by Mekki, Q A, Warrington, S J, Turner, P

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Effect of cicloprolol in intraocular pressure in healthy volunteers by Mekki, QA, Turner, P

“…Two oral doses of cicloprolol (50 mg and 100 mg), a beta 1‐adrenoceptor partial agonist, were administered to nine healthy volunteers in a double‐blind…”
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Indomethacin does not attenuate the ocular hypotensive effect of timolol by Mekki, QA, Abrams, SM, Petounis, AD, Turner, P

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A chemically stable analogue, 9 beta‐methyl carbacyclin, with similar effects to epoprostenol (prostacyclin, PGI2) in man by O'Grady, J, Hedges, A, Whittle, BJ, Al‐Sinawi, LA, Mekki, QA, Burke, C, Moody, SG, Moti, MJ, Hassan, S

“…The effects of 9 beta‐methyl carbacyclin, a chemically stable analogue of epoprostenol (prostacyclin, PGI2) were studied, in comparison with epoprostenol, both…”
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Local and systemic effects of pindolol eye drops by Mekki, QA, Penhall, R, Edgar, DF, Stewart‐Jones, JH, Turner, P

“…Local (reduction of intraocular pressure) and systemic (inhibition of exercise‐induced tachycardia) effects of 1% and 0.25% pindolol eye drops have been…”
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Safety of tacrolimus in patients with rheumatoid arthritis: long-term experience by Yocum, D. E., Furst, D. E., Bensen, W. G., Burch, F. X., Borton, M. A., Mengle-Gaw, L. J., Schwartz, B. D., Wisememandle, W., Mekki, Q. A.

“…Objective. To evaluate the long-term safety of tacrolimus 3 mg/day in patients with rheumatoid arthritis (RA). Methods. Patients with active RA who had…”
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Effect of cicloprolol in intraocular pressure in healthy vounteers by MEKKI, Q. A, TURNER, P

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Bromocriptine in glaucoma by Mekki, Q A, Turner, P

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Efficacy and safety of tacrolimus in patients with rheumatoid arthritis: A double‐blind trial by Yocum, David E., Furst, Daniel E., Kaine, Jeffrey L., Baldassare, Andrew R., Stevenson, Jon T., Borton, Mary Ann, Mengle‐Gaw, Laurel J., Schwartz, Benjamin D., Wisemandle, Wayne, Mekki, Qais A.

“…Objective To evaluate the efficacy and safety of tacrolimus as monotherapy in controlling the signs and symptoms of patients with rheumatoid arthritis (RA)…”
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Tacrolimus in rheumatoid arthritis patients receiving concomitant methotrexate: A six-month, open-label study by KREMER, Joel M, HABROS, Joseph S, KOLBA, Karen S, KAINE, Jeffrey L, BORTON, Mary Ann, MENGLE-GAW, Laurel J, SCHWARTZ, Benjamin D, WISEMANDLE, Wayne, MEKKI, Qais A

“…To assess the safety of tacrolimus used in combination with oral methotrexate (MTX) to control the signs and symptoms of rheumatoid arthritis (RA) in patients…”
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