Search Results - "Meissner, Kamila A."

Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro by Lunev, Sergey, Butzloff, Sabine, Romero, Atilio R, Linzke, Marleen, Batista, Fernando A, Meissner, Kamila A, Müller, Ingrid B, Adawy, Alaa, Wrenger, Carsten, Groves, Matthew R

“…Malaria remains a major threat to human health, as strains resistant to current therapeutics are discovered. Efforts in finding new drug targets are hampered…”
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Harnessing the Helminth Secretome for Therapeutic Immunomodulators by Anandarajah, Emmanuela M., Ditgen, Dana, Meissner, Kamila A., Brattig, Norbert, Wrenger, Carsten, Liebau, Eva

“…Helminths are the largest and most complex pathogens to invade and live within the human body. Since they are not able to outpace the immune system by rapid…”
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Drug Target Validation Methods in Malaria - Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation by Meissner, Kamila A, Lunev, Sergey, Wang, Yuan-Ze, Linzke, Marleen, de Assis Batista, Fernando, Wrenger, Carsten, Groves, Matthew R

“…The validation of drug targets in malaria and other human diseases remains a highly difficult and laborious process. In the vast majority of cases, highly…”
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Oxidative Stress Control by Apicomplexan Parasites by Wrenger, Carsten, Liebau, Eva, Izui, Natália M., Stegehake, Dirk, Zimbres, Flávia M., Meissner, Kamila Anna, Kronenberger, Thales, Bosch, Soraya S., Schettert, Isolmar

“…Apicomplexan parasites cause infectious diseases that are either a severe public health problem or an economic burden. In this paper we will shed light on how…”
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Oligomeric protein interference validates druggability of aspartate interconversion in Plasmodium falciparum by Batista, Fernando A., Bosch, Soraya S., Butzloff, Sabine, Lunev, Sergey, Meissner, Kamila A., Linzke, Marleen, Romero, Atilio R., Wang, Chao, Müller, Ingrid B., Dömling, Alexander S. S., Groves, Matthew R., Wrenger, Carsten

“…The appearance of multi‐drug resistant strains of malaria poses a major challenge to human health and validated drug targets are urgently required. To define a…”
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Indole-3-glyoxyl tyrosine: synthesis and antimalarial activity against Plasmodium falciparum by Vasconcelos, Stanley Ns, Meissner, Kamila A, Ferraz, Witor R, Trossini, Gustavo Hg, Wrenger, Carsten, Stefani, Hélio A

“…More than 40% of the world's population, across 105 countries, live in malaria endemic areas. It is estimated that about 500 million cases of malaria and half…”
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Vitamin B6-Dependent Enzymes in the Human Malaria Parasite Plasmodium falciparum : A Druggable Target? by Wrenger, Carsten, Sauer, Frank M., Coronado, Monika A., Schettert, Isolmar, Zimbres, Flávia M., Meissner, Kamila Anna, Kronenberger, Thales, Lindner, Jasmin

“…Malaria is a deadly infectious disease which affects millions of people each year in tropical regions. There is no effective vaccine available and the…”
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Indole-3-glyoxyl tyrosine: synthesis and antimalarial activity against by Vasconcelos, Stanley NS, Meissner, Kamila A, Ferraz, Witor R, Trossini, Gustavo HG, Wrenger, Carsten, Stefani, Hélio A

“…More than 40% of the world's population, across 105 countries, live in malaria endemic areas. It is estimated that about 500 million cases of malaria and half…”
Get full text