Search Results - "Meissner, Felix"

(In)Consistent Performance Feedback and the Locus of Search by Keil, Thomas, Syrigos, Evangelos, Kostopoulos, Konstantinos C., D. Meissner, Felix, G. Audia, Pino

“…Despite the prevalence and importance of multiple goals for organizations, research on how organizations respond to performance on multiple goals continues to…”
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Quantitative shotgun proteomics: considerations for a high-quality workflow in immunology by Meissner, Felix, Mann, Matthias

“…Proteomics based on high-resolution mass spectrometry has become a powerful tool for the analysis of protein abundance, modifications and interactions. Here we…”
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Mutant superoxide dismutase 1-induced IL-1β accelerates ALS pathogenesis by Meissner, Felix, Molawi, Kaaweh, Zychlinsky, Arturo

“…ALS is a fatal motor neuron disease of adult onset. Neuroinflammation contributes to ALS disease progression; however, the inflammatory trigger remains…”
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Social network architecture of human immune cells unveiled by quantitative proteomics by Rieckmann, Jan C, Geiger, Roger, Hornburg, Daniel, Wolf, Tobias, Kveler, Ksenya, Jarrossay, David, Sallusto, Federica, Shen-Orr, Shai S, Lanzavecchia, Antonio, Mann, Matthias, Meissner, Felix

“…Immune cells give rise to the most interconnected system in the body. Meissner and colleagues perform comprehensive proteomics and secretomics to describe in…”
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NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain by Stutz, Andrea, Kolbe, Carl-Christian, Stahl, Rainer, Horvath, Gabor L, Franklin, Bernardo S, van Ray, Olivia, Brinkschulte, Rebecca, Geyer, Matthias, Meissner, Felix, Latz, Eicke

“…NLRP3 is a cytosolic pattern recognition receptor that senses microbes and endogenous danger signals. Upon activation, NLRP3 forms an inflammasome with the…”
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Direct Proteomic Quantification of the Secretome of Activated Immune Cells by Meissner, Felix, Scheltema, Richard A., Mollenkopf, Hans-Joachim, Mann, Matthias

“…Protein secretion allows communication of distant cells in an organism and controls a broad range of physiological functions. We describe a quantitative,…”
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Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool by Jordan, Stefan, Tung, Navpreet, Casanova-Acebes, Maria, Chang, Christie, Cantoni, Claudia, Zhang, Dachuan, Wirtz, Theresa H., Naik, Shruti, Rose, Samuel A., Brocker, Chad N., Gainullina, Anastasiia, Hornburg, Daniel, Horng, Sam, Maier, Barbara B., Cravedi, Paolo, LeRoith, Derek, Gonzalez, Frank J., Meissner, Felix, Ochando, Jordi, Rahman, Adeeb, Chipuk, Jerry E., Artyomov, Maxim N., Frenette, Paul S., Piccio, Laura, Berres, Marie-Luise, Gallagher, Emily J., Merad, Miriam

“…Caloric restriction is known to improve inflammatory and autoimmune diseases. However, the mechanisms by which reduced caloric intake modulates inflammation…”
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C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration by May, Stephanie, Hornburg, Daniel, Schludi, Martin H., Arzberger, Thomas, Rentzsch, Kristin, Schwenk, Benjamin M., Grässer, Friedrich A., Mori, Kohji, Kremmer, Elisabeth, Banzhaf-Strathmann, Julia, Mann, Matthias, Meissner, Felix, Edbauer, Dieter

“…Hexanucleotide repeat expansion in C9orf72 is the most common pathogenic mutation in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar…”
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The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport by Pelka, Karin, Bertheloot, Damien, Reimer, Elisa, Phulphagar, Kshiti, Schmidt, Susanne V., Christ, Anette, Stahl, Rainer, Watson, Nicki, Miyake, Kensuke, Hacohen, Nir, Haas, Albert, Brinkmann, Melanie M., Marshak-Rothstein, Ann, Meissner, Felix, Latz, Eicke

“…Unc-93 homolog B1 (UNC93B1) is a key regulator of nucleic acid (NA)-sensing Toll-like receptors (TLRs). Loss of NA-sensing TLR responses in UNC93B1-deficient…”
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Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death by Tanzer, Maria C., Frauenstein, Annika, Stafford, Che A., Phulphagar, Kshiti, Mann, Matthias, Meissner, Felix

“…The inflammatory functions of the cytokine tumor necrosis factor (TNF) rely on its ability to induce cytokine production and to induce cell death…”
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Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis by Phulphagar, Kshiti, Kühn, Lars I., Ebner, Stefan, Frauenstein, Annika, Swietlik, Jonathan J., Rieckmann, Jan, Meissner, Felix

“…A major pathway for proinflammatory protein release by macrophages is inflammasome-mediated pyroptotic cell death. As conventional secretion, unconventional…”
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Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr by Salehi, Saeede, Zare, Abdolhossein, Prezza, Gianluca, Bader, Jakob, Schneider, Cornelius, Fischer, Utz, Meissner, Felix, Mann, Matthias, Briese, Michael, Sendtner, Michael

“…The neuronal RNA-binding protein Ptbp2 regulates neuronal differentiation by modulating alternative splicing programs in the nucleus. Such programs contribute…”
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Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons by Riemenschneider, Henrick, Guo, Qiang, Bader, Jakob, Frottin, Frédéric, Farny, Daniel, Kleinberger, Gernot, Haass, Christian, Mann, Matthias, Hartl, F. Ulrich, Baumeister, Wolfgang, Hipp, Mark S, Meissner, Felix, Fernández‐Busnadiego, Rubén, Edbauer, Dieter

“…Aggregation of the multifunctional RNA‐binding protein TDP‐43 defines large subgroups of amyotrophic lateral sclerosis and frontotemporal dementia and…”
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Spatiotemporal Proteomic Profiling of Huntington’s Disease Inclusions Reveals Widespread Loss of Protein Function by Hosp, Fabian, Gutiérrez-Ángel, Sara, Schaefer, Martin H., Cox, Jürgen, Meissner, Felix, Hipp, Mark S., Hartl, F.-Ulrich, Klein, Rüdiger, Dudanova, Irina, Mann, Matthias

“…Aggregation of polyglutamine-expanded huntingtin exon 1 (HttEx1) in Huntington’s disease (HD) proceeds from soluble oligomers to late-stage inclusions. The…”
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Influence of circadian clocks on adaptive immunity and vaccination responses by Ince, Louise Madeleine, Barnoud, Coline, Lutes, Lydia Kay, Pick, Robert, Wang, Chen, Sinturel, Flore, Chen, Chien-Sin, de Juan, Alba, Weber, Jasmin, Holtkamp, Stephan J., Hergenhan, Sophia Martina, Geddes-McAlister, Jennifer, Ebner, Stefan, Fontannaz, Paola, Meyer, Benjamin, Vono, Maria, Jemelin, Stéphane, Dibner, Charna, Siegrist, Claire-Anne, Meissner, Felix, Graw, Frederik, Scheiermann, Christoph

“…The adaptive immune response is under circadian control, yet, why adaptive immune reactions continue to exhibit circadian changes over long periods of time is…”
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Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed by Kveler, Ksenya, Starosvetsky, Elina, Ziv-Kenet, Amit, Kalugny, Yuval, Gorelik, Yuri, Shalev-Malul, Gali, Aizenbud-Reshef, Netta, Dubovik, Tania, Briller, Mayan, Campbell, John, Rieckmann, Jan C, Asbeh, Nuaman, Rimar, Doron, Meissner, Felix, Wiser, Jeff, Shen-Orr, Shai S

“…Interactions between hundreds of immune cells and cytokines in disease are mined from PubMed. Cytokines are signaling molecules secreted and sensed by immune…”
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Evidence of Extrapancreatic Glucagon Secretion in Man by Lund, Asger, Bagger, Jonatan I, Wewer Albrechtsen, Nicolai J, Christensen, Mikkel, Grøndahl, Magnus, Hartmann, Bolette, Mathiesen, Elisabeth R, Hansen, Carsten P, Storkholm, Jan H, van Hall, Gerrit, Rehfeld, Jens F, Hornburg, Daniel, Meissner, Felix, Mann, Matthias, Larsen, Steen, Holst, Jens J, Vilsbøll, Tina, Knop, Filip K

“…Glucagon is believed to be a pancreas-specific hormone, and hyperglucagonemia has been shown to contribute significantly to the hyperglycemic state of patients…”
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Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation by Swietlik, Jonathan J., Bärthel, Stefanie, Falcomatà, Chiara, Fink, Diana, Sinha, Ankit, Cheng, Jingyuan, Ebner, Stefan, Landgraf, Peter, Dieterich, Daniela C., Daub, Henrik, Saur, Dieter, Meissner, Felix

“…Cell-selective proteomics is a powerful emerging concept to study heterocellular processes in tissues. However, its high potential to identify…”
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Interaction of 7SK with the Smn complex modulates snRNP production by Ji, Changhe, Bader, Jakob, Ramanathan, Pradhipa, Hennlein, Luisa, Meissner, Felix, Jablonka, Sibylle, Mann, Matthias, Fischer, Utz, Sendtner, Michael, Briese, Michael

“…Gene expression requires tight coordination of the molecular machineries that mediate transcription and splicing. While the interplay between transcription…”
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Hepatitis C virus enters liver cells using the CD81 receptor complex proteins calpain-5 and CBLB by Bruening, Janina, Lasswitz, Lisa, Banse, Pia, Kahl, Sina, Marinach, Carine, Vondran, Florian W, Kaderali, Lars, Silvie, Olivier, Pietschmann, Thomas, Meissner, Felix, Gerold, Gisa

“…Hepatitis C virus (HCV) and the malaria parasite Plasmodium use the membrane protein CD81 to invade human liver cells. Here we mapped 33 host protein…”
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