Search Results - "Meiring, S. M."

The thrombin generation capability of the Chacma baboon (Papio ursinus): implications for haemostatic disease models by Joubert, J., Meiring, S. M., Janse van Rensburg, W. J.

“…Baboon models are often used to investigate haemostatic diseases, such as acquired thrombotic thrombocytopenic purpura or bacterial sepsis-induced disseminated…”
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The effects of streptokinase in a Chacma baboon (Papio ursinus) model of acquired thrombotic thrombocytopenic purpura by Joubert, J., Meiring, S. M., Conradie, C., Lamprecht, S., Janse van Rensburg, W. J.

“…TTP is a life-threatening disorder with limited pharmaceutical treatment options. Recently, the potential of streptokinase in the treatment of acquired TTP was…”
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Comparison of ADAMTS13 and Von Willebrand factor levels and activities, and plasminogen levels, in plasma products currently available for the treatment of thrombotic thrombocytopenic purpura in South Africa by van Marle, A.C., Joubert, J., Meiring, S.M.

“…Thrombotic thrombocytopenic purpura (TTP) results from a deficiency in the Von Willebrand factor (VWF) cleaving protease, ADAMTS13. Treatment involves plasma…”
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The Use of Phage Display and Yeast Based Expression System for the Development of a Von Willebrand Factor Propeptide Assay: Development of a Von Willebrand Factor Propeptide Assay by Bragg, R. R., Theron, C., Setlai, B. D. P., Meiring, S. M.

“…Background. The diagnosis of von Willebrand disease is complex due to the heterogeneity of the disease. About eighty percent of von Willebrand disease patients…”
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Sites of elimination and pharmacokinetics of recombinant [131I]lepirudin in baboons by Meiring, S M, Lötter, M G, Badenhorst, P N, Bucha, E, Nowak, G, Kotzé, H F

“…Lepirudin has a short half-life, and only 50-60% of the intravenously administered dose is excreted by the kidneys. The fate of the remainder is unknown. We…”
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Development of an inhibitory antibody fragment to human tissue factor using phage display technology by Meiring, S.M., Vermeulen, J., Badenhorst, P.N.

“…Tissue factor is involved in the etiology of thrombotic diseases initiating the thrombosis associated with the inflammation that occurs during infection. The…”
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In vitro effect of a thrombin inhibition peptide selected by phage display technology by Meiring, Muriel S, Litthauer, Derek, Hársfalvi, Jolan, van Wyk, Veronica, Badenhorst, Philip N, Kotzé, Harry F

“…A repeated selection of phages from a cyclic heptapeptide phage display library resulted in the enrichment of phages that bind to human α-thrombin. One clone…”
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