Search Results - "Meiring, S."

The thrombin generation capability of the Chacma baboon (Papio ursinus): implications for haemostatic disease models by Joubert, J., Meiring, S. M., Janse van Rensburg, W. J.

“…Baboon models are often used to investigate haemostatic diseases, such as acquired thrombotic thrombocytopenic purpura or bacterial sepsis-induced disseminated…”
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Eliminating exogenous insulin therapy in patients with type 2 diabetes by duodenal ablation and GLP-1RA decreases risk scores for cardiovascular events by Meiring, S, Busch, C B E, van Baar, A C G, Hemke, R, Holleman, F, Nieuwdorp, M, Bergman, J J G H M

“…Duodenal Mucosal Resurfacing (DMR) is an endoscopic ablation technique aimed at improving glycaemia and metabolic health in patients with type 2 diabetes…”
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Prolonged shedding of SARS-CoV-2 at high viral load amongst hospitalised immunocompromised persons living with HIV in South Africa by Meiring, S., Tempia, S., Bhiman, J., Kleynhans, J., Buys, A., Makhasi, M., Mcmorrow, M., Moyes, J., Quan, V., Walaza, S., Plessis, M. Du, Wolter, N., Von Gottberg, A., Cohen, C.

“…There is limited information on SARS-CoV-2 shedding duration amongst persons living with HIV (PLWH). We hypothesised that PLWH shed SARS-CoV-2 for longer…”
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The effects of streptokinase in a Chacma baboon (Papio ursinus) model of acquired thrombotic thrombocytopenic purpura by Joubert, J., Meiring, S. M., Conradie, C., Lamprecht, S., Janse van Rensburg, W. J.

“…TTP is a life-threatening disorder with limited pharmaceutical treatment options. Recently, the potential of streptokinase in the treatment of acquired TTP was…”
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Comparison of ADAMTS13 and Von Willebrand factor levels and activities, and plasminogen levels, in plasma products currently available for the treatment of thrombotic thrombocytopenic purpura in South Africa by van Marle, A.C., Joubert, J., Meiring, S.M.

“…Thrombotic thrombocytopenic purpura (TTP) results from a deficiency in the Von Willebrand factor (VWF) cleaving protease, ADAMTS13. Treatment involves plasma…”
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The Use of Phage Display and Yeast Based Expression System for the Development of a Von Willebrand Factor Propeptide Assay: Development of a Von Willebrand Factor Propeptide Assay by Bragg, R. R., Theron, C., Setlai, B. D. P., Meiring, S. M.

“…Background. The diagnosis of von Willebrand disease is complex due to the heterogeneity of the disease. About eighty percent of von Willebrand disease patients…”
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An economic model for introducing a quadrivalent conjugate meningococcal vaccine among adolescents in South Africa by Lengana, S.G.P, von Gottberg, A, Meiring, S, von Mollendorf, C, Moyes, J, Cohen, C

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Evaluation of an influenza vaccination campaign among pregnant women in two provinces in South Africa, 2015 by Lengana, S.G.P, McMorrow, M, Tshangela, A, Meiring, S, Nunes, M, Cutland, C, Itzikowitz, R, Isaacs, W, Madhi, S, Cohen, C

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Factors associated with mortality among patients with candidaemia in South Africa, 2012 by Smidt, M.C. Fortuin-de, Meiring, S, Mpembe, R, Kularatane, R, Govender, N

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Zoonotic infections in adults in the Bushbuckridge District of Mpumalanga Province by Quan, V.C, Frean, J, Simpson, G, Knobel, D, Meiring, S, Weyer, J, Rossouw, J, Blumberg, L

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A decade of invasive meningococcal disease surveillance in South Africa: 2003-2012 by Meiring, S, Cohen, C, de Gouveia, L, Plessis, M. du, Lengana, S, von Mollendorf, C, Hoosen, A, Kularatne, R, Lekalakala, R, Naby, F, Naicker, P, Reubenson, G, Seetharam, S, Zell, E, von Gottberg, A

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Shem, Ham, Japheth and Zuma – Genesis 9:25-27 and masculinities in South Africa by Meiring, Jacob JS

“…The article explores the interpretation and reception of Genesis 9:25-27 and how the so-called ‘curse of Ham’ contributed to the construction of…”
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Development of an inhibitory antibody fragment to human tissue factor using phage display technology by Meiring, S.M., Vermeulen, J., Badenhorst, P.N.

“…Tissue factor is involved in the etiology of thrombotic diseases initiating the thrombosis associated with the inflammation that occurs during infection. The…”
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Tirofiban versus abciximab: tirofiban is administered at suboptimal dosages when evaluated in an arterial thrombosis model in non-human primates by van Rensburg, Walter J. Janse, Roodt, Jan P., Lamprecht, Seb, Meiring, S. Muriel, Badenhorst, Philip N.

“…To prevent thrombosis in high-risk acute coronary syndrome patients undergoing percutaneous coronary intervention for re-vascularisation, concomitant…”
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Risk factors for death amongst children of five years and younger, with invasive non-typhoidal Salmonella infection, 2004 – 2008, South Africa by Dermaux, V, Sooka, A, Meiring, S, Govender, N, Moyes, J, Cohen, C, Keddy, K

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In vitro effect of a thrombin inhibition peptide selected by phage display technology by Meiring, Muriel S, Litthauer, Derek, Hársfalvi, Jolan, van Wyk, Veronica, Badenhorst, Philip N, Kotzé, Harry F

“…A repeated selection of phages from a cyclic heptapeptide phage display library resulted in the enrichment of phages that bind to human α-thrombin. One clone…”
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Sites of elimination and pharmacokinetics of recombinant [131I]lepirudin in baboons by Meiring, S M, Lötter, M G, Badenhorst, P N, Bucha, E, Nowak, G, Kotzé, H F

“…Lepirudin has a short half-life, and only 50-60% of the intravenously administered dose is excreted by the kidneys. The fate of the remainder is unknown. We…”
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Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium by Shaw, David, Abad, Raquel, Amin-Chowdhury, Zahin, Bautista, Adriana, Bennett, Desiree, Broughton, Karen, Cao, Bin, Casanova, Carlo, Choi, Eun Hwa, Chu, Yiu-Wai, Claus, Heike, Coelho, Juliana, Corcoran, Mary, Cottrell, Simon, Cunney, Robert, Cuypers, Lize, Dalby, Tine, Davies, Heather, de Gouveia, Linda, Deghmane, Ala-Eddine, Demczuk, Walter, Desmet, Stefanie, Domenech, Mirian, Drew, Richard, du Plessis, Mignon, Duarte, Carolina, Erlendsdóttir, Helga, Fry, Norman K, Fuursted, Kurt, Hale, Thomas, Henares, Desiree, Henriques-Normark, Birgitta, Hilty, Markus, Hoffmann, Steen, Humphreys, Hilary, Ip, Margaret, Jacobsson, Susanne, Johnson, Christopher, Johnston, Jillian, Jolley, Keith A, Kawabata, Aníbal, Kozakova, Jana, Kristinsson, Karl G, Krizova, Pavla, Kuch, Alicja, Ladhani, Shamez, Lâm, Thiên-Trí, León, María Eugenia, Lindholm, Laura, Litt, David, Maiden, Martin C J, Martin, Irene, Martiny, Delphine, Mattheus, Wesley, McCarthy, Noel D, Meehan, Mary, Meiring, Susan, Mölling, Paula, Morfeldt, Eva, Morgan, Julie, Mulhall, Robert, Muñoz-Almagro, Carmen, Murdoch, David, Murphy, Joy, Musilek, Martin, Mzabi, Alexandre, Novakova, Ludmila, Oftadeh, Shahin, Perez-Argüello, Amaresh, Pérez-Vázquez, Maria, Perrin, Monique, Perry, Malorie, Prevost, Benoit, Roberts, Maria, Rokney, Assaf, Ron, Merav, Sanabria, Olga Marina, Scott, Kevin J, Sheppard, Carmen, Siira, Lotta, Sintchenko, Vitali, Skoczyńska, Anna, Sloan, Monica, Slotved, Hans-Christian, Smith, Andrew J, Steens, Anneke, Taha, Muhamed-Kheir, Toropainen, Maija, Tzanakaki, Georgina, Vainio, Anni, van der Linden, Mark P G, van Sorge, Nina M, Varon, Emmanuelle, Vohrnova, Sandra, von Gottberg, Anne, Yuste, Jose, Zanella, Rosemeire, Zhou, Fei, Brueggemann, Angela B

“…The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by…”
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Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003–2008 by von Gottberg, Anne, Cohen, Cheryl, de Gouveia, Linda, Meiring, Susan, Quan, Vanessa, Whitelaw, Andrew, Crowther-Gibson, Penny, Madhi, Shabir A, Whitney, Cynthia G, Klugman, Keith P

“…Highlights • Infants <1 year had up to 6-fold higher rates of disease than older children. • HIV-infected infants had a 21-fold greater risk of disease. •…”
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Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South Africa by COHEN, Cheryl, SINGH, Elvira, WU, Henry M, MARTIN, Stacey, DE GOUVEIA, Linda, KLUGMAN, Keith P, MEIRING, Susan, GOVENDER, Nelesh, VON GOTTBERG, Anne

“…We aimed to compare the incidence of meningococcal disease amongst HIV-infected and uninfected individuals and to evaluate whether HIV is a risk factor for…”
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