Search Results - "Meir Drexler, Shira"
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Don’t fear ‘fear conditioning’: Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear
Published in Neuroscience and biobehavioral reviews (01-06-2017)“…•Originates from discussions on replicability and researcher’s degrees of freedom.•Aims at stimulating discussions on methods applied in fear conditioning…”
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Navigating the garden of forking paths for data exclusions in fear conditioning research
Published in eLife (16-12-2019)“…In this report, we illustrate the considerable impact of researcher degrees of freedom with respect to exclusion of participants in paradigms with a learning…”
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The role of glucocorticoids in emotional memory reconsolidation
Published in Neurobiology of learning and memory (01-07-2017)“…[Display omitted] •Glucocorticoids have a critical role in emotional memory reconsolidation.•Their effect is mediated by glucocorticoids receptors in the…”
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Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning
Published in Neuroscience and biobehavioral reviews (01-12-2019)“…•Considers methodological comparability of translational research in fear conditioning in rodents and humans.•Equips researchers with practical and…”
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Effects of Cortisol on Reconsolidation of Reactivated Fear Memories
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2015)“…The return of conditioned fear after successful extinction (eg, following exposure therapy) is a significant problem in the treatment of anxiety disorders and…”
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Reactivation of the Unconditioned Stimulus Inhibits the Return of Fear Independent of Cortisol
Published in Frontiers in behavioral neuroscience (12-11-2019)“…Reconsolidation is the post-retrieval stabilization of memories, a time-limited process during which reactivated (i.e., retrieved) memories can be updated with…”
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How stress and glucocorticoids timing-dependently affect extinction and relapse
Published in Neuroscience and biobehavioral reviews (01-03-2019)“…[Display omitted] •Extinction learning is the most important underlying mechanism of exposure therapy.•Recent studies show that glucocorticoids, e.g. cortisol,…”
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Behavioral Disruption of Memory Reconsolidation: From Bench to Bedside and Back Again
Published in Behavioral neuroscience (01-02-2018)“…During the postretrieval reconsolidation "window", memories can be disrupted, strengthened, or updated using various pharmacological and behavioral…”
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Stress effects on memory retrieval of aversive and appetitive instrumental counterconditioning in men
Published in Neurobiology of learning and memory (01-12-2022)“…Extinction training creates a second inhibitory memory trace and effectively reduces conditioned responding. However, acute stress inhibits the retrieval of…”
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Stress disrupts the reconsolidation of fear memories in men
Published in Psychoneuroendocrinology (01-03-2017)“…Graphical abstract…”
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Stress before extinction learning enhances and generalizes extinction memory in a predictive learning task
Published in Neurobiology of learning and memory (01-05-2017)“…•The context-specificity of extinction memory often leads to renewal.•Yet stress prior to learning can impair the integration of contextual cues.•Our results…”
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Cortisol effects on fear memory reconsolidation in women
Published in Psychopharmacology (01-07-2016)“…Rationale Previous work from our group has shown that cortisol enhances fear reconsolidation in men. Whether similar effects can be observed in women remains…”
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Effects of Postretrieval-Extinction Learning on Return of Contextually Controlled Cued Fear
Published in Behavioral neuroscience (01-08-2014)“…Reactivation of an already consolidated memory makes it labile for a period of several hrs, which are required for its reconsolidation. Evidence suggests that…”
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Boosting extinction success with a stressor: Timing is critical
Published in Psychoneuroendocrinology (01-02-2019)Get full text
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Preextinction Stress Prevents Context-Related Renewal of Fear
Published in Behavior therapy (01-11-2018)“…Extinction learning, which creates new safety associations, is thought to be the mechanism underlying exposure therapy, commonly used for the treatment of…”
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A global experiment on motivating social distancing during the COVID-19 pandemic
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2022)“…Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This…”
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A global experiment on motivating social distancing during the COVID-19 pandemic
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2022)“…Finding communication strategies that effectively motivate social distancing continues to be a global public health priority during the COVID-19 pandemic. This…”
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Stress modulation of fear and extinction in psychopathology and treatment
Published in Neuroforum (25-09-2020)“…The glucocorticoid cortisol, a major player in the development of stress-related psychopathology, can also be used for the augmentation of extinction-based…”
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The impact of stress and glucocorticoids on extinction and reconsolidation of emotional memories
Published in Psychoneuroendocrinology (01-11-2015)Get full text
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The effects of cortisol on human fear memory reconsolidation
Published in Psychoneuroendocrinology (01-11-2015)Get full text
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