Search Results - "Meinema, C"
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Protein biogenesis machinery is a driver of replicative aging in yeast
Published in eLife (01-12-2015)“…An integrated account of the molecular changes occurring during the process of cellular aging is crucial towards understanding the underlying mechanisms. Here,…”
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DNA circles promote yeast ageing in part through stimulating the reorganization of nuclear pore complexes
Published in eLife (04-04-2022)“…The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and in many species, it changes composition as the organism ages…”
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The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome
Published in Molecular biology of the cell (15-12-2013)“…The basket of the nuclear pore complex (NPC) is generally depicted as a discrete structure of eight protein filaments that protrude into the nucleoplasm and…”
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Saccharomyces cerevisiae goes through distinct metabolic phases during its replicative lifespan
Published in eLife (09-04-2019)“…A comprehensive description of the phenotypic changes during cellular aging is key towards unraveling its causal forces. Previously, we mapped age-related…”
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The transport of integral membrane proteins across the nuclear pore complex
Published in Nucleus (Austin, Tex.) (01-07-2012)“…The nuclear envelope protects and organizes the genome. The nuclear pore complexes embedded in the nuclear envelope allow selective transport of macromolecules…”
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Integrated Quantification and Identification of Aldehydes and Ketones in Biological Samples
Published in Analytical chemistry (Washington) (20-05-2014)“…The identification of unknown compounds remains to be a bottleneck of mass spectrometry (MS)-based metabolomics screening experiments. Here, we present a novel…”
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A karyopherin acts in localized protein synthesis
Published in Cell cycle (Georgetown, Tex.) (01-04-2010)“…Multiple mechanisms are in place to regulate adequate synthesis of proteins, ranging from ways to ensure sequence fidelity, polypeptide folding and protein…”
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Quantitative Analysis of Membrane Protein Transport Across the Nuclear Pore Complex
Published in Traffic (Copenhagen, Denmark) (01-05-2013)“…Nuclear transport of the Saccharomyces cerevisiae membrane proteins Src1/Heh1 and Heh2 across the NPC is facilitated by a long intrinsically disordered linker…”
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Flexible and Extended Linker Domains Support Efficient Targeting of Heh2 to the Inner Nuclear Membrane
Published in Structure (London) (04-02-2020)“…The nuclear pore complex (NPC) is embedded in the nuclear envelope and forms the main gateway to the nuclear interior including the inner nuclear membrane…”
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State-selective electron transfer and ionization in collisions of highly charged ions with ground-state Na(3 s ) and laser-excited Na (3 p )
Published in Physical review. A, Atomic, molecular, and optical physics (21-02-2012)“…Single electron transfer and ionization in collisions of N super(51) and Ne super(81) with ground state Na(3s) and laser excited Na (3p) are investigated both…”
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Nuclear transport factor directs localization of protein synthesis during mitosis
Published in Nature cell biology (01-04-2013)Get full text
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Long Unfolded Linkers Facilitate Membrane Protein Import Through the Nuclear Pore Complex
Published in Science (American Association for the Advancement of Science) (01-07-2011)“…Active nuclear import of soluble cargo involves transport factors that shuttle cargo through the nuclear pore complex (NPC) by binding to phenylalanine-glycine…”
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Nuclear transport factor directs localization of protein synthesis during mitosis
Published in Nature cell biology (01-03-2009)“…Export of messenger RNA from the transcription site in the nucleus and mRNA targeting to the translation site in the cytoplasm are key regulatory processes in…”
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In silico approaches and the role of ontologies in aging research
Published in Rejuvenation research (01-12-2013)“…The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means. A…”
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First test of Lorentz invariance in the weak decay of polarized nuclei
Published in Physical review. D, Particles, fields, gravitation, and cosmology (15-10-2013)“…A new test of Lorentz invariance in the weak interactions has been made by searching for variations in the decay rate of spin-polarized super(20)Na nuclei…”
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Traveling-wave deceleration of SrF molecules
Published in Journal of molecular spectroscopy (01-06-2014)“…[Display omitted] •We present the first deceleration of SrF molecules.•We have demonstrated the stability of a modular traveling-wave decelerator.•This opens…”
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A gas cell for stopping, storing and polarizing radioactive particles
Published in Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment (21-06-2016)“…A radioactive beam of 20Na is stopped in a gas cell filled with Ne gas. The stopped particles are polarized by optical pumping. The degree of polarization that…”
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Erratum: Nuclear transport factor directs localization of protein synthesis during mitosis
Published in Nature cell biology (02-04-2013)“…Nat. Cell Biol. 11, 350–356 (2009); published online 8th February 2009; corrected online 12th March 2013 In a follow-up study of our paper, we discovered that…”
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Test of Lorentz invariance in $\beta$ decay of polarized $^{20}\text{Na}
Published 12-08-2016“…Phys. Rev. C 94, 025503 (2016) We search for a dependence of the lifetime of $^{20}\text{Na}$ nuclei on the nuclear spin direction. Such a directional…”
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