Search Results - "Meier, Carola"
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Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior
Published in Nature communications (16-03-2022)“…Cortical neural circuits are complex but very precise networks of balanced excitation and inhibition. Yet, the molecular and cellular mechanisms that form the…”
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Tenogenesis of Decellularized Porcine Achilles Tendon Matrix Reseeded with Human Tenocytes in the Nude Mice Xenograft Model
Published in International journal of molecular sciences (15-07-2018)“…Cultivation of autologous human tenocytes in a cell-free xenogenic extracellular tendon matrix (xECM) could present an approach for tendon reconstruction. The…”
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3
Toward Higher Sensitivity in Quantitative MALDI Imaging Mass Spectrometry of CNS Drugs Using a Nonpolar Matrix
Published in Analytical chemistry (Washington) (06-11-2018)“…Tissue-specific ion suppression is an unavoidable matrix effect in MALDI mass spectrometry imaging (MALDI-MSI), the negative impact of which on precision and…”
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4
Acid sphingomyelinase deficiency enhances myelin repair after acute and chronic demyelination
Published in PloS one (05-06-2017)“…The cuprizone animal model, also known as the toxic demyelination model, is a well-reproducible model of demyelination- and remyelination in mice, and has been…”
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Discerning the spatio-temporal disease patterns of surgically induced OA mouse models
Published in PloS one (11-04-2019)“…Osteoarthritis (OA) is the most common cause of disability in ageing societies, with no effective therapies available to date. Two preclinical models are…”
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Neuroglial activation and Cx43 expression are reduced upon transplantation of human umbilical cord blood cells after perinatal hypoxic-ischemic injury
Published in Brain research (03-12-2012)“…Abstract Glial cells play a crucial role in the pathomechanism of perinatal hypoxic-ischemic brain injury (HI) and are involved in the maintenance of a chronic…”
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MALDI Mass Spectral Imaging of Bile Acids Observed as Deprotonated Molecules and Proton-Bound Dimers from Mouse Liver Sections
Published in Journal of the American Society for Mass Spectrometry (01-04-2018)“…Bile acids (BAs) play two vital roles in living organisms, as they are involved in (1) the secretion of cholesterol from liver, and (2) the lipid…”
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Transplantation of human umbilical cord blood cells mediated beneficial effects on apoptosis, angiogenesis and neuronal survival after hypoxic-ischemic brain injury in rats
Published in Cell and tissue research (01-06-2012)“…Transplantation of human umbilical cord blood (hucb) cells in a model of hypoxic-ischemic brain injury led to the amelioration of lesion-impaired neurological…”
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The chemokine SDF-1/CXCL12 contributes to the 'homing' of umbilical cord blood cells to a hypoxic-ischemic lesion in the rat brain
Published in Journal of neuroscience research (01-05-2010)“…Previous studies have shown that transplanted human umbilical cord blood (hUCB)‐derived mononuclear cells exert therapeutic effects in various animal models of…”
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10
Degeneration of Lumbar Intervertebral Discs: Characterization of Anulus Fibrosus Tissue and Cells of Different Degeneration Grades
Published in International journal of molecular sciences (21-03-2020)“…Intervertebral disc (IVD) herniation and degeneration is a major source of back pain. In order to regenerate a herniated and degenerated disc, closure of the…”
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Pathways toward a Decarbonized Future—Impact on Security of Supply and System Stability in a Sustainable German Energy System
Published in Energies (Basel) (01-02-2021)“…Pathways leading to a carbon neutral future for the German energy system have to deal with the expected phase-out of coal-fired power generation, in addition…”
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Human umbilical cord blood cells restore brain damage induced changes in rat somatosensory cortex
Published in PloS one (01-06-2011)“…Intraperitoneal transplantation of human umbilical cord blood (hUCB) cells has been shown to reduce sensorimotor deficits after hypoxic ischemic brain injury…”
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First Responders to Hyperosmotic Stress in Murine Astrocytes: Connexin 43 Gap Junctions Are Subject to an Immediate Ultrastructural Reorganization
Published in Biology (Basel, Switzerland) (09-12-2021)“…In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap…”
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Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells
Published in Pediatric research (01-02-2006)“…Brain damage around birth may cause lifelong neurodevelopmental deficits. We examined the therapeutic potential of human umbilical cord blood-derived…”
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15
Freeze fracture: new avenues for the ultrastructural analysis of cells in vitro
Published in Histochemistry and cell biology (01-01-2018)Get full text
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16
Infrapatellar Fat Pad Modulates Osteoarthritis-Associated Cytokine and MMP Expression in Human Articular Chondrocytes
Published in Cells (Basel, Switzerland) (01-12-2023)“…Osteoarthritis (OA) most frequently affects the knee joint and is associated with an elevated expression of cytokines and extracellular cartilage matrix (ECM),…”
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A Monoclonal Human Alveolar Epithelial Cell Line (“Arlo”) with Pronounced Barrier Function for Studying Drug Permeability and Viral Infections
Published in Advanced science (01-03-2023)“…In the development of orally inhaled drug products preclinical animal models regularly fail to predict pharmacological as well as toxicological responses in…”
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The influence of IL-10 and TNFα on chondrogenesis of human mesenchymal stromal cells in three-dimensional cultures
Published in International journal of molecular sciences (09-09-2014)“…Chondrogenic differentiated mesenchymal stromal cells (MSCs) are a promising cell source for articular cartilage repair. This study was undertaken to determine…”
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IL-17C and IL-17RE Promote Wound Closure in a Staphylococcus aureus-Based Murine Wound Infection Model
Published in Microorganisms (Basel) (27-08-2021)“…The epithelial cytokine interleukin-17C (IL-17C) mediates inflammation through the interleukin 17 receptor E (IL-17RE). Prior studies showed a detrimental role…”
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Differential distribution of probenecid as detected by on-tissue mass spectrometry
Published in Cell and tissue research (01-05-2015)“…We demonstrate, by means of on-tissue mass spectrometry of tissue sections, that the drug probenecid can penetrate the blood–brain barrier. This method holds…”
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