Search Results - "Mehta, Satish K"
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Herpes Virus Reactivation in Astronauts During Spaceflight and Its Application on Earth
Published in Frontiers in microbiology (07-02-2019)“…Latent herpes virus reactivation has been demonstrated in astronauts during shuttle (10-16 days) and International Space Station (≥180 days) flights. Following…”
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2
NK cell function is impaired during long-duration spaceflight
Published in Journal of applied physiology (1985) (01-04-2019)“…Maintaining astronaut health during space travel is paramount for further human exploration of the solar system beyond Earth's orbit. Of concern are potential…”
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3
Effect of Simulated Cosmic Radiation on Cytomegalovirus Reactivation and Lytic Replication
Published in International journal of molecular sciences (01-10-2024)“…Human exploration of the solar system will expose crew members to galactic cosmic radiation (GCR), with a potential for adverse health effects. GCR particles…”
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4
Latent virus reactivation in astronauts on the international space station
Published in NPJ microgravity (12-04-2017)“…Reactivation of latent herpes viruses was measured in 23 astronauts (18 male and 5 female) before, during, and after long-duration (up to 180 days) spaceflight…”
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5
Time-resolved molecular measurements reveal changes in astronauts during spaceflight
Published in Frontiers in physiology (14-07-2023)“…From the early days of spaceflight to current missions, astronauts continue to be exposed to multiple hazards that affect human health, including low gravity,…”
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6
Silent Reactivation of Varicella Zoster Virus in Pregnancy: Implications for Maintenance of Immunity to Varicella
Published in Viruses (30-06-2022)“…We encountered two cases of varicella occurring in newborn infants. Because the time between birth and the onset of the illness was much shorter than the…”
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Asymptomatic reactivation and shed of infectious varicella zoster virus in astronauts
Published in Journal of medical virology (01-06-2008)“…Varicella zoster virus (VZV) causes varicella (chickenpox), after which virus becomes latent in ganglia along the entire neuraxis. Virus reactivation produces…”
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8
Inhibition of Human Cytomegalovirus Entry into Host Cells Through a Pleiotropic Small Molecule
Published in International journal of molecular sciences (29-02-2020)“…Human cytomegalovirus (HCMV) infections are wide-spread among the general population with manifestations ranging from asymptomatic to severe developmental…”
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9
Immunoglobulines And Protein Profiles in Burn Patients
Published in Indian journal of plastic surgery (15-09-2023)“…Abstract The Serum immunoglobulins IgG, IgA, and IgM following burns remain subnormal for 7 days and return to normalcy by 14th to 21st day. Infection,…”
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10
Reactivation of Latent Epstein-Barr Virus: A Comparison after Exposure to Gamma, Proton, Carbon, and Iron Radiation
Published in International journal of molecular sciences (28-09-2018)“…Among the many stressors astronauts are exposed to during spaceflight, cosmic radiation may lead to various serious health effects. Specifically, space…”
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11
Dermatitis during Spaceflight Associated with HSV-1 Reactivation
Published in Viruses (11-04-2022)“…Human alpha herpesviruses herpes simplex virus (HSV-1) and varicella zoster virus (VZV) establish latency in various cranial nerve ganglia and often reactivate…”
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Localization of VZV in saliva of zoster patients
Published in Journal of medical virology (01-09-2017)“…Varicella zoster virus (VZV) in saliva from six herpes zoster patients and one chickenpox patient was found to be exclusively associated with epithelial cells…”
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13
Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station
Published in The journal of allergy and clinical immunology. Global (01-05-2024)“…A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The…”
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14
Stress-induced subclinical reactivation of varicella zoster virus in astronauts
Published in Journal of medical virology (01-01-2004)“…Varicella zoster virus (VZV) becomes latent in human ganglia after primary infection. VZV reactivation occurs primarily in elderly individuals, organ…”
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15
Spaceflight modulates gene expression in the whole blood of astronauts
Published in NPJ microgravity (08-12-2016)“…Astronauts are exposed to a unique combination of stressors during spaceflight, which leads to alterations in their physiology and potentially increases their…”
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16
Varicella-Zoster Virus in the Saliva of Patients with Herpes Zoster
Published in The Journal of infectious diseases (01-03-2008)“…Fifty-four patients with herpes zoster were treated with valacyclovir. On treatment days 1, 8, and 15, pain was scored and saliva examined for varicella-zoster…”
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Decreases in thymopoiesis of astronauts returning from space flight
Published in JCI insight (04-08-2016)“…Following the advent of molecular assays that measure T cell receptor excision circles (TRECs) present in recent thymic emigrants, it has been conclusively…”
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The Dynamics of Herpesvirus and Polyomavirus Reactivation and Shedding in Healthy Adults: A 14-Month Longitudinal Study
Published in The Journal of infectious diseases (15-05-2003)“…Humans are infected with viruses that establish long-term persistent infections. To address whether immunocompetent individuals control virus reactivation…”
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19
Reactivation and Shedding of Cytomegalovirus in Astronauts during Spaceflight
Published in The Journal of infectious diseases (01-12-2000)“…The reactivation of cytomegalovirus (CMV) in 71 astronauts was investigated, using polymerase chain reaction. A significantly greater (P < .0001) shedding…”
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20
Viremia in Acute Herpes Zoster
Published in The Journal of infectious diseases (01-07-2009)“…Background. A phase 2 trial was conducted to evaluate the efficacy of a topical antiviral, sorivudine, as an adjuvant to valacyclovir for the treatment of…”
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