Search Results - "Mehta, Ratnesh B"

CD4+ T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases by Badam, Tejaswi V., Hellberg, Sandra, Mehta, Ratnesh B., Lechner-Scott, Jeannette, Lea, Rodney A., Tost, Jorg, Mariette, Xavier, Svensson-Arvelund, Judit, Nestor, Colm E., Benson, Mikael, Berg, Göran, Jenmalm, Maria C., Gustafsson, Mika, Ernerudh, Jan

“…Epigenetics may play a central, yet unexplored, role in the profound changes that the maternal immune system undergoes during pregnancy and could be involved…”
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The human fetal placenta promotes tolerance against the semiallogeneic fetus by inducing regulatory T cells and homeostatic M2 macrophages by Svensson-Arvelund, Judit, Mehta, Ratnesh B, Lindau, Robert, Mirrasekhian, Elahe, Rodriguez-Martinez, Heriberto, Berg, Göran, Lash, Gendie E, Jenmalm, Maria C, Ernerudh, Jan

“…A successful pregnancy requires that the maternal immune system is instructed to a state of tolerance to avoid rejection of the semiallogeneic fetal-placental…”
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Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects by Verma, Deepti, Parasa, Venkata Ramanarao, Raffetseder, Johanna, Martis, Mihaela, Mehta, Ratnesh B., Netea, Mihai, Lerm, Maria

“…The reason for the largely variable protective effect against TB of the vaccine Bacille Calmette-Guerin (BCG) is not understood. In this study, we investigated…”
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Maintained thymic output of conventional and regulatory T cells during human pregnancy by Hellberg, Sandra, Mehta, Ratnesh B., Forsberg, Anna, Berg, Göran, Brynhildsen, Jan, Winqvist, Ola, Jenmalm, Maria C., Ernerudh, Jan

“…During pregnancy, immunological tolerance toward the semiallogeneic fetus needs to be established while at the same time an effective immune defense must be…”
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Human first-trimester trophoblasts promote a tolerant fetal environment by inducing homeostatic macrophages and regulatory T cells through M-CSF, IL10, TGF(, and sTRAIL by Svensson-Arvelund, Judit, Mehta, Ratnesh B, Lindau, Robert, Mirrasekhian, Elahe, Freland, Sofia, Rodriguez-Martinez, Heriberto, Lash, Gendie, Berg, Göran, Jenmalm, Maria C, Ernerudh, Jan

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