Search Results - "Mehta, R.G"

Antioxidant Xanthones from the Pericarp of Garcinia mangostana (Mangosteen) by Jung, Hyun-Ah, Su, Bao-Ning, Keller, William J, Mehta, Rajendra G, Kinghorn, A. Douglas

“…As part of ongoing research on cancer chemopreventive agents from botanical dietary supplements, Garcinia mangostana L. (commonly known as mangosteen) was…”
Get full text

Actions of vitamin D are mediated by the TLR4 pathway in inflammation-induced colon cancer by Murillo, G., Nagpal, V., Tiwari, N., Benya, R.V., Mehta, R.G.

“…Many chronic inflammatory diseases are associated with increased risk of developing cancer. In the colon, strong support for a link between chronic…”
Get full text

Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems by Gafner, Stefan, Lee, Sang-Kook, Cuendet, Muriel, Barthélémy, Sophie, Vergnes, Laurent, Labidalle, Serge, Mehta, Rajendra G., Boone, Charles W., Pezzuto, John M.

“…Curcumin ( 1) and 22 curcumin analogs have been evaluated in cancer chemoprevention models. The substitution pattern on the aromatic moiety proved to be…”
Get full text

Experimental basis for the prevention of breast cancer by Mehta, R.G

“…Cancer chemoprevention involves intervention in the carcinogenic process by a natural or synthetic chemical that either blocks neoplasia development or arrests…”
Get full text

Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest by Murillo, G, Salti, G.I, Kosmeder II, J.W, Pezzuto, J.M, Mehta, R.G

“…As previously demonstrated, deguelin [(7aS, BaS)-13, 13a-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzo-pyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one mediates…”
Get full text

Potential cancer chemopreventive constituents of the seeds of Dipteryx odorata (tonka bean) by Jang, D.S, Park, E.J, Hawthorne, M.E, Vigo, J.S, Graham, J.G, Cabieses, F, Santarsiero, B.D, Mesecar, A.D, Fong, H.H.S, Mehta, R.G

“…A new cassane diterpene, dipteryxic acid (1), and a new isoflavonolignan, 5-methoxyxanthocercin A (2), as well as four known active compounds,…”
Get full text

Zapotin, a Phytochemical Present in a Mexican Fruit, Prevents Colon Carcinogenesis by Murillo, G, Hirschelman, W.H, Ito, A, Moriarty, R.M, Kinghorn, A.D, Pezzuto, J.M, Mehta, R.G

“…Zapotin (5,6,2',6'-tetramethoxyflavone), found in the tropical fruit zapote blanco (Casimiroa edulis), is consumed in many parts of the world, including…”
Get full text

Potential Cancer Chemopreventive Flavonoids from the Stems of Tephrosia toxicaria by Jang, Dae Sik, Park, Eun Jung, Kang, Young-Hwa, Hawthorne, Michael E., Vigo, Jose Schunke, Graham, James G., Cabieses, Fernando, Fong, Harry H. S., Mehta, Rajendra G., Pezzuto, John M., Kinghorn, A. Douglas

“…A new butenylflavanone, (2S)-5-hydroxy-7-methoxy-8-[(E)-3-oxo-1-butenyl]flavanone (1), and a new rotenoid, 4‘,5‘-dihydro-11,5‘-dihydroxy-4‘-methoxytephrosin…”
Get full text

Induction of differentiation by 1α-hydroxyvitamin D 5 in T47D human breast cancer cells and its interaction with vitamin D receptors by Lazzaro, G, Agadir, A, Qing, W, Poria, M, Mehta, R.R, Moriarty, R.M, Das Gupta, T.K, Zhang, X.-K, Mehta, R.G

“…The role of the active metabolite of vitamin D, 1,25 dihydroxyvitamin D 3 (1,25(OH) 2D 3), in cell differentiation is well established. However, its use as a…”
Get full text

Induction of differentiation by 1α-hydroxyvitamin D5 in T47D human breast cancer cells and its interaction with vitamin D receptors by LAZZARO, G, AGADIR, A, QING, W, PORIA, M, MEHTA, R. R, MORIARTY, R. M, DAS GUPTA, T. K, ZHANG, X.-K, MEHTA, R. G

Get full text

Flavonoid Constituents of Chorizanthe diffusa with Potential Cancer Chemopreventive Activity by Chung, Ha Sook, Chang, Leng Chee, Lee, Sang Kook, Shamon, Lisa A, van Breemen, Richard B, Mehta, Rajendra G, Farnsworth, Norman R, Pezzuto, John M, Kinghorn, A. Douglas

“…An ethyl acetate-soluble extract of Chorizanthe diffusa was found to exhibit significant antioxidant activity, as judged by scavenging stable…”
Get full text

Angoline and Chelerythrine, Benzophenanthridine Alkaloids That Do Not Inhibit Protein Kinase C by Lee, Sang Kook, Qing, Wei Guo, Mar, Woongchon, Luyengi, Lumonadio, Mehta, Rajendra G., Kawanishi, Kazuko, Fong, Harry H.S., Beecher, Christopher W.W., Kinghorn, A. Douglas, Pezzuto, John M.

“…Starting with an extract derived from the stem ofMacleaya cordata (Papaveraceae) that was active in the process of inhibiting phorbol 12,13-dibutyrate binding…”
Get full text

Antimutagenic Constituents of Casimiroa edulis with Potential Cancer Chemopreventive Activity by Ito, Aiko, Shamon, Lisa A, Yu, Boyang, Mata-Greenwood, Eugenia, Lee, Sang Kook, Mehta, Rajendra G, Farnsworth, Norman R, Fong, Harry H. S, Pezzuto, John M, Kinghorn, A. Douglas

“…An ethyl acetate extract derived from the seeds of the medicinal and food plant Casimiroa edulis inhibited mutagenicity induced by…”
Get full text

Metabolism of N-[4-hydroxyphenyl]retinamide (4-HPR) to N-[4-methoxyphenyl]retinamide (4-MPR) may serve as a biomarker for its efficacy against human breast cancer and melanoma cells by Mehta, R.R., Hawthorne, M.E., Graves, J.M., Mehta, R.G.

“…A clinical trial of N-[4-hydroxyphenyl]retinamide (4-HPR) has been in progress for the past 4 years to evaluate its role in chemoprevention of breast cancer…”
Get full text

A Novel Fuzzy Based Classification for Data Mining Using Fuzzy Discretization by Mehta, R.G., Rana, D.P., Zaveri, M.A.

“…Data mining is a process to discover useful, possibly unexpected, patterns from the large set of data and widely used in the large information processing…”
Get full text

Therapeutic effect of N-(4-hydroxyphenyl)retinamide on N-methyl-N-nitrosourea-induced rat mammary cancer by Dowlatshahi, K, Mehta, R G, Thomas, C F, Dinger, N M, Moon, R C

“…Virgin Sprague--Dawley rats received a single i.v. injection of 40 mg N-methyl-N-nitrosourea (MNU)/kg body wt. at 50 days of age. After the first palpable…”
Get more information

Metabolism of the chemopreventive retinoid N-(4-hydroxyphenyl)retinamide by mammary gland in organ culture by Mehta, R.G, Hultin, T.A, Moon, R.C

“…N-(4-Hydroxyphenyl)retinamide (4-HPR) is considered to be the most effective chemopreventive retinoid for chemically induced mammary carcinogenesis in rats…”
Get full text

Retinoid glucuronides do not interact with retinoid binding proteins by Mehta, R G, Barua, A B, Olson, J A, Moon, R C

“…Retinoid glucuronides have recently been described as water soluble, biologically active retinoids. In mouse mammary gland organ cultures retinoyl glucuronide,…”
Get more information

Anticarcinogenic effects of retinoids in animals by Moon, R C, Mehta, R G

“…Retinoids are effective inhibitors of chemical carcinogenesis in the skin, mammary gland, esophagus, respiratory tract, pancreas, and urinary bladder of…”
Get more information

Effect of all-trans-retinoic acid on nuclear RNA polymerase activity in chemically-induced rat mammary tumors by Mehta, R G, Hawthorne, M E, Moon, R C

“…In the present study the effect of all-trans-retinoic acid (RA) on nuclear RNA polymerase activity in N-methyl-N-nitrosourea (MNU)-induced mammary tumors was…”
Get more information