Search Results - "Mehta, P M"

Human Papillomavirus E7 Enhances Hypoxia-Inducible Factor 1―Mediated Transcription by Inhibiting Binding of Histone Deacetylases by BODILY, Jason M, MEHTA, Kavi P. M, LAIMINS, Laimonis A

“…Infection by human papillomaviruses (HPV) leads to the formation of benign lesions, warts, and in some cases, cervical cancer. The formation of these lesions…”
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The E7 Open Reading Frame Acts in cis and in trans To Mediate Differentiation-Dependent Activities in the Human Papillomavirus Type 16 Life Cycle by BODILY, Jason M, MEHTA, Kavi P. M, CRUZ, Linda, MEYERS, Craig, LAIMINS, Laimonis A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Clinical Outcomes of Proton Radiotherapy for Uveal Melanoma by Verma, V, Mehta, M.P

“…Abstract Aims Although clinical experience with proton beam radiotherapy (PBT) for most tumours is limited, there is relatively longstanding experience for…”
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CHK1 phosphorylates PRIMPOL to promote replication stress tolerance by Mehta, Kavi P M, Thada, Vaughn, Zhao, Runxiang, Krishnamoorthy, Archana, Leser, Micheal, Lindsey Rose, Kristie, Cortez, David

“…Replication-coupled DNA repair and damage tolerance mechanisms overcome replication stress challenges and complete DNA synthesis. These pathways include fork…”
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Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial by Brown, Paul D, Pugh, Stephanie, Laack, Nadia N, Wefel, Jeffrey S, Khuntia, Deepak, Meyers, Christina, Choucair, Ali, Fox, Sherry, Suh, John H, Roberge, David, Kavadi, Vivek, Bentzen, Soren M, Mehta, Minesh P, Watkins-Bruner, Deborah

“…To determine the protective effects of memantine on cognitive function in patients receiving whole-brain radiotherapy (WBRT). Adult patients with brain…”
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Advances in Acute Ischemic Stroke Treatment: Current Status and Future Directions by Bathla, G, Ajmera, P, Mehta, P M, Benson, J C, Derdeyn, C P, Lanzino, G, Agarwal, A, Brinjikji, W

“…The management of acute ischemic stroke has undergone a paradigm shift in the past decade. This has been spearheaded by the emergence of endovascular…”
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Amifostine and radiation therapy: past, present, and future by Tannehill, S P, Mehta, M P

“…Preclinical studies demonstrate that amifostine has the potential to selectively protect normal tissues from the harmful effects of radiation without…”
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Multicenter Phase Ib/II Trial of the Radiation Enhancer Motexafin Gadolinium in Patients With Brain Metastases by CARDE, Patrice, TIMMERMAN, Robert, MEHTA, Minesh P, KOPROWSKI, Christopher D, FORD, Judith, TISHLER, Roy B, MILES, Dale, MILLER, Richard A, RENSCHLER, Markus F

“…Motexafin gadolinium is a magnetic resonance imaging (MRI)--detectable redox active drug that localizes selectively in tumor cells and enhances the effect of…”
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Gadolinium in human glioblastoma cells for gadolinium neutron capture therapy by DE STASIO, Gelsomina, CASALBORE, Patrizia, PERRET, Didier, MOGK, David W, PERFETTI, Paolo, MEHTA, Minesh P, MERCANTI, Delio, PALLINI, Roberto, GILBERT, Benjamin, SANITA, Francesca, CIOTTI, Maria Teresa, ROSI, Giancarlo, FESTINESI, Armando, LAROCCA, Luigi Maria, RINELLI, Alessandro

“…157Gd is a potential agent for neutron capture cancer therapy (GdNCT). We directly observed the microdistribution of Gd in cultured human glioblastoma cells…”
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A multiinstitutional outcome and prognostic factor analysis of radiosurgery for resectable single brain metastasis by Auchter, R M, Lamond, J P, Alexander, E, Buatti, J M, Chappell, R, Friedman, W A, Kinsella, T J, Levin, A B, Noyes, W R, Schultz, C J, Loeffler, J S, Mehta, M P

“…Recent randomized trials of selected patients with single brain metastasis comparing resection followed by whole-brain radiotherapy (WBRT) to WBRT alone have…”
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Phase I study of paclitaxel in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report by Chang, S M, Kuhn, J G, Rizzo, J, Robins, H I, Schold, Jr, S C, Spence, A M, Berger, M S, Mehta, M P, Bozik, M E, Pollack, I, Gilbert, M, Fulton, D, Rankin, C, Malec, M, Prados, M D

“…To determine the maximum-tolerated dose (MTD) of paclitaxel administered as a 3-hour infusion in patients with recurrent malignant glioma. Patients were…”
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Phase II study of paclitaxel in patients with recurrent malignant glioma by Prados, M D, Schold, S C, Spence, A M, Berger, M S, McAllister, L D, Mehta, M P, Gilbert, M R, Fulton, D, Kuhn, J, Lamborn, K, Rector, D J, Chang, S M

“…To assess the efficacy and toxicity of paclitaxel administered as a 3-hour infusion to patients with recurrent malignant glioma. Adult patients with recurrent…”
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Defining the role of radiosurgery in the management of brain metastases by Mehta, M P, Rozental, J M, Levin, A B, Mackie, T R, Kubsad, S S, Gehring, M A, Kinsella, T J

“…The role of stereotactic radiosurgery in the management of recurrent and newly diagnosed brain metastases was evaluated prospectively. From December 1988 to…”
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Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability by Bhowmick, Rahul, Mehta, Kavi P.M., Lerdrup, Mads, Cortez, David

“…DNA replication preferentially initiates close to active transcription start sites (TSSs) in the human genome. Transcription proceeds discontinuously with an…”
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Effect of amifostine on toxicities associated with sequential chemotherapy and radiation therapy for unresectable non-small-cell lung cancer: results of a phase II trial by Tannehill, S P, Mehta, M P, Larson, M, Storer, B, Pellet, J, Kinsella, T J, Schiller, J H

“…To determine the effect of amifostine on the safety and efficacy of induction chemotherapy with high-dose cisplatin and vinblastine followed by large-field…”
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Phase II trial of hyperfractionated accelerated radiation therapy for nonresectable non-small-cell lung cancer: results of Eastern Cooperative Oncology Group 4593 by Mehta, M P, Tannehill, S P, Adak, S, Martin, L, Petereit, D G, Wagner, H, Fowler, J F, Johnson, D

“…To assess the feasibility, toxicity, and efficacy of hyperfractionated accelerated radiation therapy (HART) for non-small-cell lung cancer (NSCLC). Thirty…”
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HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA by Mohni, Kareem N., Wessel, Sarah R., Zhao, Runxiang, Wojciechowski, Andrea C., Luzwick, Jessica W., Layden, Hillary, Eichman, Brandt F., Thompson, Petria S., Mehta, Kavi P.M., Cortez, David

“…Abasic sites are one of the most common DNA lesions. All known abasic site repair mechanisms operate only when the damage is in double-stranded DNA. Here, we…”
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Relationship between fat-to-fat-free mass ratio and decrements in leg strength after downhill running by Hickner, R. C, Mehta, P. M, Dyck, D, Devita, P, Houmard, J. A, Koves, T, Byrd, P

“…Human Performance Laboratory, Department of Exercise and Sports Science, East Carolina University, Greenville, North Carolina 27858 The purpose of this study…”
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HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation by Mehta, Kavi P.M., Lovejoy, Courtney A., Zhao, Runxiang, Heintzman, Darren R., Cortez, David

“…5-Hydroxymethylcytosine (5hmC) binding, ES-cell-specific (HMCES) crosslinks to apurinic or apyrimidinic (AP, abasic) sites in single-strand DNA (ssDNA). To…”
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Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling by Dollins, D. Eric, Bai, Wenli, Fridy, Peter C., Otto, James C., Neubauer, Julie L., Gattis, Samuel G., Mehta, Kavi P. M., York, John D.

“…Inositol diphosphates (PP-IPs), also known as inositol pyrophosphates, are high-energy cellular signaling codes involved in nutrient and regulatory responses…”
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