Search Results - "Mehta, Arpesh"

Therapeutic potential of CERE-110 (AAV2-NGF): Targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons by Bishop, Kathie M., Hofer, Eva K., Mehta, Arpesh, Ramirez, Anthony, Sun, Liangwu, Tuszynski, Mark, Bartus, Raymond T.

“…Treatment of degenerating basal forebrain cholinergic neurons with nerve growth factor (NGF) in Alzheimer's disease has long been contemplated, but an…”
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Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone by Fleming, Sheila M., Zhu, Chunni, Fernagut, Pierre-Olivier, Mehta, Arpesh, DiCarlo, Cheryl D., Seaman, Ronald L., Chesselet, Marie-Françoise

“…Mitochondrial toxins such as the complex 1 inhibitor rotenone are widely used as pesticides and may be present in military environments. Administration of…”
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Effect of GABAA receptor stimulation in the subthalamic nucleus on motor deficits induced by nigrostriatal lesions in the rat by Mehta, Arpesh, Chesselet, Marie-Françoise

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Effect of GABA A receptor stimulation in the subthalamic nucleus on motor deficits induced by nigrostriatal lesions in the rat by Mehta, Arpesh, Chesselet, Marie-Françoise

“…Inhibition of the subthalamic nucleus by lesions or GABAergic agonists improves motor symptoms in monkeys or humans with a loss of nigrostriatal dopaminergic…”
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527. CERE-110, an AAV2-Based Vector To Deliver NGF, Provides Trophic Activity to Basal Forebrain Cholinergic Neurons in Rats and Cynomolgous Monkeys by Bishop, Kathie M, Hofer, Katrin, Rius, Denise, Mehta, Arpesh, Lawandry, Shokry, Brown, Lamar, Kruegel, Brian, Gasmi, Mehdi, Tuszynski, Mark, Bartus, Raymond T

“…Numerous studies indicate that providing trophic support to degenerating basal forebrain cholinergic neurons with nerve growth factor (NGF) is a logical…”
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539. Biodistribution and Safety Profile of CERE-110 (AAV2-NGF) Delivered to the Rodent Brain by Landers, Mark, Austin, Melissa, Kwok, Kevin, Ketchum, Eli, Lin, Richard, Manlapaz, Leo, Mehta, Arpesh, Fernandez, Javier, Gasmi, Mehdi, Vacante, Dominick, Bartus, Raymond T, Bishop, Kathie, Printz, Marie

“…Preventing the atrophy and death of basal forebrain cholinergic neurons via gene transfer of NGF is a promising approach for the treatment of Alzheimer's…”
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Endomorphin-1: Induction of Motor Behavior and Lack of Receptor Desensitization by Mehta, Arpesh, Bot, George, Reisine, Terry, Chesselet, Marie-Francoise

“…The endomorphins are recently discovered endogenous agonists for the mu-opioid receptor (Zadina et al., 1997). Endomorphins produce analgesia; however, their…”
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Increased m-CPP-induced oral dyskinesia after lesion of serotonergic neurons by Mehta, Arpesh, Eberle-Wang, Kim, Chesselet, Marie-Françoise

“…Peripheral administration of the 5-hydroxytryptamine (5-HT) 2C/1B agonist 1-( m-chlorophenyl)piperazine ( m-CPP) produces abnormal orofacial movements in rats…”
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Increased behavioral response to dopaminergic stimulation of the subthalamic nucleus after nigrostriatal lesions by Mehta, Arpesh, Thermos, Kyriaki, Chesselet, Marie-Françoise

“…Local infusions of the nonselective dopaminergic agonist apomorphine into the subthalamic nucleus of rats has been shown to elicit orofacial dyskinesia which…”
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