Search Results - "Mehta, A. K"

Shape selection and multi-stability in helical ribbons by Guo, Q., Mehta, A. K., Grover, M. A., Chen, W., Lynn, D. G., Chen, Z.

“…Helical structures, almost ubiquitous in biological systems, have inspired the design and manufacturing of helical devices with applications in…”
Get full text

Fecal Microbiota Transplantation for Refractory Clostridium difficile Colitis in Solid Organ Transplant Recipients by Friedman‐Moraco, R. J., Mehta, A. K., Lyon, G. M., Kraft, C. S.

“…Fecal microbiota transplantation (FMT) has been shown to be safe and efficacious in individuals with refractory Clostridium difficile. It has not been widely…”
Get full text

Renal Transplantation Using Belatacept Without Maintenance Steroids or Calcineurin Inhibitors by Kirk, A. D., Guasch, A., Xu, H., Cheeseman, J., Mead, S. I., Ghali, A., Mehta, A. K., Wu, D., Gebel, H., Bray, R., Horan, J., Kean, L. S., Larsen, C. P., Pearson, T. C.

“…Kidney transplantation remains limited by toxicities of calcineurin inhibitors (CNIs) and steroids. Belatacept is a less toxic CNI alternative, but existing…”
Get full text

The Allo‐ and Viral‐Specific Immunosuppressive Effect of Belatacept, but Not Tacrolimus, Attenuates With Progressive T Cell Maturation by Xu, H., Perez, S. D., Cheeseman, J., Mehta, A. K., Kirk, A. D.

“…Tacrolimus impairs allo‐ and viral‐specific T cell responses. Belatacept, a costimulation‐based alternative to tacrolimus, has emerged with a paradoxical…”
Get full text

Selective Targeting of Human Alloresponsive CD8+ Effector Memory T Cells Based on CD2 Expression by Lo, D. J., Weaver, T. A., Stempora, L., Mehta, A. K., Ford, M. L., Larsen, C. P., Kirk, A. D.

“…Costimulation blockade (CoB), specifically CD28/B7 inhibition with belatacept, is an emerging clinical replacement for calcineurin inhibitor‐based…”
Get full text

High CTLA‐4 Expression on Th17 Cells Results in Increased Sensitivity to CTLA‐4 Coinhibition and Resistance to Belatacept by Krummey, S. M., Cheeseman, J. A., Conger, J. A., Jang, P. S., Mehta, A. K., Kirk, A. D., Larsen, C. P., Ford, M. L.

“…The CD28/cytotoxic T‐lymphocyte antigen 4 (CTLA‐4) blocker belatacept selectively inhibits alloreactive T cell responses but is associated with a high…”
Get full text

Belatacept and Sirolimus Prolong Nonhuman Primate Renal Allograft Survival Without a Requirement for Memory T Cell Depletion by Lo, D. J., Anderson, D. J., Weaver, T. A., Leopardi, F., Song, M., Farris, A. B., Strobert, E. A., Jenkins, J., Turgeon, N. A., Mehta, A. K., Larsen, C. P., Kirk, A. D.

“…Belatacept is an inhibitor of CD28/B7 costimulation that is clinically indicated as a calcineurin inhibitor (CNI) alternative in combination with mycophenolate…”
Get full text

Crop geometry and nitrogen management impacts on cotton cultivar H-1098(i) productivity by MALIK, KAPIL, MEHTA, A K, THAKRAL, S K, ABHILASH, ABHILASH

“…A field investigation was undertaken to study plant geometry and nitrogen management on performance of cotton variety H-1098 (i). The experiment was conducted…”
Get full text

Choline supplementation reduces oxidative stress in mouse model of allergic airway disease by Mehta, A. K., Arora, N., Gaur, S. N., Singh, B. P.

“…Background  Asthma is a multi‐factorial inflammatory disease associated with increased oxidative stress and altered antioxidant defences. We have evaluated the…”
Get full text

Gateway-like absurdly benign traversable wormhole solutions by Mehta, A. K.

“…A class of wormhole solutions is constructed that has restricted polar degrees of freedom to achieve a gateway-like configuration. This compels the use of…”
Get full text

Inhibition of αvβ6 Promotes Acute Renal Allograft Rejection in Nonhuman Primates by Lo, D. J., Farris, A. B., Song, M., Leopardi, F., Anderson, D. J., Strobert, E. A., Ramakrishnan, S., Turgeon, N. A., Mehta, A. K., Turnbull, B., Maroni, B., Violette, S. M., Kirk, A. D.

“…The integrin αvβ6 activates latent transforming growth factor‐β (TGF‐β) within the kidney and may be a target for the prevention of chronic allograft fibrosis…”
Get full text

Antagonism of stimulation-produced analgesia by naloxone and N-methyl-D-aspartate: role of opioid and N-methyl-D-aspartate receptors by Mehta, A K, Halder, S, Khanna, N, Tandon, O P, Sharma, K K

“…The present study aims to investigate the influence of electrical stimulation of periaqueductal gray (PAG) following peripheral nerve injury and its modulation…”
Get more information

Effect of choline chloride in allergen-induced mouse model of airway inflammation by Mehta, A. K, Gaur, S. N, Arora, N, Singh, B. P

“…The incidence of asthma has increased the world over, and current therapies for the disease suffer from potential side-effects. This has created an opportunity…”
Get full text

Tumor necrosis factor family member LIGHT acts with IL‐1β and TGF‐β to promote airway remodeling during rhinovirus infection by Mehta, A. K., Doherty, T., Broide, D., Croft, M.

“…Background Rhinovirus (RV) can exacerbate allergen‐driven asthma. However, it has been suggested that serial infections with RV may also lead to asthma‐like…”
Get full text

A Novel Framework for Identifying the Interactions between Biophysical and Social Components of an Agricultural System: A Guide for Improving Wheat Production in Haryana, NW India by Coventry, D. R, Poswal, R. S, Yadav, Ashok, Zhou, Yi, Riar, Amritbir, Kumar, Anuj, Sharma, R. K, Chhokar, R. S, Gupta, R. K, Mehta, A. K, Chand, Ramesh, Denton, M. D, Cummins, J. A

“…Purpose: The purpose of this study is to develop a conceptual framework with related analysis methodologies that identifies the influence of social environment…”
Get full text

Allergenicity assessment of transgenic mustard (Brassica juncea) expressing bacterial codA gene by Singh, A. K., Mehta, A. K., Sridhara, S., Gaur, S. N., Singh, B. P., Sarma, P. U., Arora, N.

“…Background:  Assessing the allergenicity and toxicity of genetically modified (GM) crops is essential before they become a regular part of our food supply. The…”
Get full text

Lessons Learned: Early Termination of a Randomized Trial of Calcineurin Inhibitor and Corticosteroid Avoidance Using Belatacept by Newell, K. A., Mehta, A. K., Larsen, C. P., Stock, P. G., Farris, A. B., Mehta, S. G., Ikle, D., Armstrong, B., Morrison, Y., Bridges, N., Robien, M., Mannon, R. B.

“…The intent of this National Institutes of Health–sponsored study was to compare a belatacept‐based immunosuppressive regimen with a maintenance regimen of…”
Get full text

Effect of knee position on the ultrasound elastography appearance of the patellar tendon by Berko, N.S, Mehta, A.K, Levin, T.L, Schulz, J.F

“…Highlights • Ultrasound elastography examination of the patellar tendon is not standardized. • Patellar tendon elasticity varies with knee position. •…”
Get full text

Potassium channel openers exhibit cross-tolerance with morphine in two experimental models of pain by Khanna, N, Malhotra, R S, Mehta, A K, Garg, G R, Halder, S, Sharma, K K

“…The study was performed to assess the effect of potassium channel openers on morphine tolerance and vice-versa. Swiss albino mice of either gender weighing…”
Get more information

Ebola Virus Disease: Implications for Solid Organ Transplantation by Kaul, D. R., Mehta, A. K., Wolfe, C. R., Blumberg, E., Green, M.

“…The authors recommend a simple, common‐sense approach to screening deceased and living donors for exposure to Ebola virus and thus reducing the risk of Ebola…”
Get full text