Search Results - "Mehrotra, N."

Optimizing Oncology Therapeutics Through Quantitative Translational and Clinical Pharmacology: Challenges and Opportunities by Venkatakrishnan, K, Friberg, LE, Ouellet, D, Mettetal, JT, Stein, A, Trocóniz, IF, Bruno, R, Mehrotra, N, Gobburu, J, Mould, DR

“…Despite advances in biomedical research that have deepened our understanding of cancer hallmarks, resulting in the discovery and development of targeted…”
Get full text

Insulin Glargine in Type 1 Diabetes Mellitus: A Review of Clinical Trials and Real-world Evidence Across Two Decades by Saboo, Banshi, Chandalia, Hemraj, Ghosh, Sujoy, Kesavadev, Jothydev, Kochar, I P S, Prasannakumar, K M, Sarda, Archana, Bantwal, Ganapathi, Mehrotra, R N, Rai, Madhukar

“…Over the past two decades, insulin glargine 100 U/mL (Gla-100) has emerged as the "standard of care" basal insulin for the management of type 1 diabetes…”
Get more information

The role of pharmacokinetics and pharmacodynamics in phosphodiesterase-5 inhibitor therapy by MEHROTRA, N, GUPTA, M, KOVAR, A, MEIBOHM, B

“…Differences in clinical pharmacology of the currently marketed phosphodiesterase (PDE)5 inhibitors sildenafil, vardenafil and tadalafil are largely determined…”
Get full text

Correlation of mRNA delivery timing and protein expression in lipid-based transfection by Reiser, A, Woschée, D, Mehrotra, N, Krzysztoń, R, Strey, H H, Rädler, J O

“…Non-viral gene delivery is constrained by the dwell time that most synthetic nucleic acid nanocarriers spend inside endosomal compartments. In order to…”
Get full text

Exposure-Response Relationship of T-DM1: Insight Into Dose Optimization for Patients With HER2-Positive Metastatic Breast Cancer by Wang, J, Song, P, Schrieber, S, Liu, Q, Xu, Q, Blumenthal, G, Amiri Kordestani, L, Cortazar, P, Ibrahim, A, Justice, R, Wang, Y, Tang, S, Booth, B, Mehrotra, N, Rahman, A

“…Exposure–response (E–R) analyses for ado‐trastuzumab emtansine (T‐DM1, Kadcyla) were performed using data from a randomized, active control (lapatinib plus…”
Get full text

Fixed-dose combination in management of type 2 diabetes mellitus: Expert opinion from an international panel by Kalra, Sanjay, Das, A, Priya, G, Ghosh, S, Mehrotra, R, Das, S, Shah, P, Bajaj, S, Deshmukh, V, Sanyal, D, Chandrasekaran, S, Khandelwal, D, Joshi, A, Nair, T, Eliana, F, Permana, H, Fariduddin, M, Shrestha, P, Shrestha, D, Kahandawa, S, Sumanathilaka, M, Shaheed, A, Rahim, A, Orabi, A, Al-ani, A, Hussein, W, Kumar, D, Shaikh, K

“…Type 2 diabetes mellitus (T2DM) is a progressive disease with multifactorial etiology. The first-line therapy includes monotherapy (with metformin), which…”
Get full text

Long-term outcomes of sigmoid vaginoplasty in patients with disorder of sexual development - our experience by Bhaskar, Ved, Sinha, Rahul, Mehrotra, Seema, Mehrotra, C, Singh, Vishwajeet

“…Introduction: To report our experience with sigmoid vaginoplasty in patients with different forms of disorder of sexual development and their long-term…”
Get full text

Is This the Dose for You?: The Role of Modeling by Huang, S-M, Bhattaram, A, Mehrotra, N, Wang, Y

“…To make an informed benefit–risk evaluation of a drug, a range of doses needs to be evaluated and its dose–response and exposure–response relationships for…”
Get full text

Utility of Precision Medicine in the Management of Diabetes: Expert Opinion from an International Panel by Kalra, Sanjay, Das, A. K., Bajaj, Sarita, Priya, Gagan, Ghosh, Sujoy, Mehrotra, R. N., Das, Sambit, Shah, Parag, Deshmukh, Vaishali, Sanyal, Debmalya, Chandrasekaran, Sruti, Khandelwal, Deepak, Joshi, Amaya, Nair, Tiny, Eliana, Fatimah, Permana, Hikmat, Fariduddin, M. D., Shrestha, Pradeep Krishna, Shrestha, Dina, Kahandawa, Shayaminda, Sumanathilaka, Manilka, Shaheed, Ahamed, Rahim, Aly Ahmed Abdel, Orabi, Abbas, Al-ani, Ahmed, Hussein, Wiam, Kumar, Dinesh, Shaikh, Khalid

“…Aim The primary objective of this review is to develop a practice-based expert group opinion on the role of precision medicine with a specific focus on…”
Get full text

Effect of copper on growth, yield and concentration of Fe, Mn, Zn and Cu in wheat plants (Triticum aestivum L.) by Kumar, Ratan, Mehrotra, N K, Nautiyal, B D, Kumar, Praveen, Singh, P K

“…A pot experiment was conducted at six graded levels of copper (Cu) viz., 0, 0.5, 1.0, 1.5, 2.0 and 2.5 mg kg(-1) to test the response of wheat plants grown in…”
Get more information

Primary tuberculosis of urethra presenting as stricture urethra and watering can perineum: A rarity by Prakash, Gaurav, Singh, Vishwajeet, Sinha, Rahul, Babu, Suresh, Jhanwar, Ankur, Mehrotra, C

“…A young man presented with irritative lower urinary tract symptoms and multiple fistulae (watering can) in the perineum since 6 months. Micturating…”
Get full text

Giant vestibular schwannomas: focusing on the differences between the solid and the cystic variants by Mehrotra, N., Behari, S., Pal, L., Banerji, D., Sahu, R. N., Jain, V. K.

“…In vestibular schwannomas (VS), the tumour size, as well as the size of the cystic component, have a considerable bearing on the outcome. This study addresses…”
Get full text

NATO Eastward Expansion and Russian Security by Mehrotra, O. N.

Get full text

57. Pedicled buccal pad fat flap for reconstruction of early oral cancer tumours by Samaiya, A, Mehrotra, N, Rai, R, Singh, M.P, Goyal, H, Hassan, A

Get full text

Postmenopausal osteoporosis: Our experience by Mehrotra, R N, Ranjan, Alok, Lath, Rahul, Ratnam, R

“…There is very little published literature about experience with osteoporosis treatment from our country. It is a retrospective analysis of first 50 patients…”
Get full text

Genetic variability in Asparagus racemosus (Willd.) from Madhya Pradesh, India by random amplified polymorphic DNA by Vijay, N, Sairkar, P, Silawat, N, Garg, R K, Mehrotra, N N

“…Random amplified polymorphic DNA (RAPD) markers were used to assess genetic diversity in Asparagus racemosus (Willd.) an important medicinal plant collected…”
Get full text

Early Triassic palynomorphs from Manuguru area of Godavari graben, Andhra Pradesh by Jha, Neerja, Pauline Sabina, K., Mehrotra, N. C.

“…Palynological analysis of the subsurface sediments from the bore hole 1008 (PK-6&7 blocks) from Manuguru area of Godavari graben has revealed the presence of…”
Get full text

RAPD analysis for genetic diversity of two populations of Mystus vittatus (Bloch) of Madhya Pradesh, India by Garg, R K, Silawat, N, Sairkar, P, Vijay, N, Mehrotra, N N

“…The random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR) was applied to analyze the genetic variation of the 2 populations of Mystus vittatus…”
Get full text

Palynological dating and correlation of surface and subsurface sediments from Wardha valley coalfield, Maharashtra by Jha, Neerja, Sabina, Pauline, Rajni Tewari, K., Mehrotra, N. C.

“…42 genera of palynomorphs have been reported from the qualitative and quantitative analysis of the palynoflora from both open cast mine and bore holes viz.,…”
Get full text

A large waterborne viral hepatitis E epidemic in Kanpur, India by NAIK, S. R, AGGARWAL, R, SALUNKE, P. N, MEHROTRA, N. N

“…In 1991 the largest epidemic of viral hepatitis E yet reported occurred in Kanpur (population, 2.1 million), India. The incidence of icteric hepatitis from…”
Get full text