Search Results - "Mehrabadi, Farid"

A Transcriptionally Distinct Subpopulation of Healthy Acinar Cells Exhibit Features of Pancreatic Progenitors and PDAC by Gopalan, Vishaka, Singh, Arashdeep, Rashidi Mehrabadi, Farid, Wang, Li, Ruppin, Eytan, Arda, H Efsun, Hannenhalli, Sridhar

“…Pancreatic ductal adenocarcinoma (PDAC) tumors can originate either from acinar or ductal cells in the adult pancreas. We re-analyze multiple pancreas and PDAC…”
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Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models by Liu, Yuelin, Li, Xuan Cindy, Rashidi Mehrabadi, Farid, Schäffer, Alejandro A, Pratt, Drew, Crawford, David R, Malikić, Salem, Molloy, Erin K, Gopalan, Vishaka, Mount, Stephen M, Ruppin, Eytan, Aldape, Kenneth D, Sahinalp, S Cenk

“…Recent studies exploring the impact of methylation in tumor evolution suggest that although the methylation status of many of the CpG sites are preserved…”
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Genome-wide profiling of transcription factor activity in primary liver cancer using single-cell ATAC sequencing by Craig, Amanda J., Silveira, Maruhen A. Datsch, Ma, Lichun, Revsine, Mahler, Wang, Limin, Heinrich, Sophia, Rae, Zachary, Ruchinskas, Allison, Dadkhah, Kimia, Do, Whitney, Behrens, Shay, Mehrabadi, Farid R., Dominguez, Dana A., Forgues, Marshonna, Budhu, Anuradha, Chaisaingmongkol, Jittiporn, Hernandez, Jonathan M., Davis, Jeremy L., Tran, Bao, Marquardt, Jens U., Ruchirawat, Mathuros, Kelly, Michael, Greten, Tim F., Wang, Xin W.

“…Primary liver cancer (PLC) consists of two main histological subtypes; hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). The role of…”
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Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer by Roper, Nitin, Brown, Anna-Leigh, Wei, Jun S., Pack, Svetlana, Trindade, Christopher, Kim, Chul, Restifo, Olivia, Gao, Shaojian, Sindiri, Sivasish, Mehrabadi, Farid, El Meskini, Rajaa, Ohler, Zoe Weaver, Maity, Tapan K., Venugopalan, Abhilash, Cultraro, Constance M., Akoth, Elizabeth, Padiernos, Emerson, Chen, Haobin, Kesarwala, Aparna, Smart, DeeDee K., Nilubol, Naris, Rajan, Arun, Piotrowska, Zofia, Xi, Liqiang, Raffeld, Mark, Panchenko, Anna R., Sahinalp, Cenk, Hewitt, Stephen, Hoang, Chuong D., Khan, Javed, Guha, Udayan

“…Clonal evolution of osimertinib-resistance mechanisms in EGFR mutant lung adenocarcinoma is poorly understood. Using multi-region whole-exome and RNA…”
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PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem by Sadeqi Azer, Erfan, Rashidi Mehrabadi, Farid, Malikić, Salem, Li, Xuan Cindy, Bartok, Osnat, Litchfield, Kevin, Levy, Ronen, Samuels, Yardena, Schäffer, Alejandro A, Gertz, E Michael, Day, Chi-Ping, Pérez-Guijarro, Eva, Marie, Kerrie, Lee, Maxwell P, Merlino, Glenn, Ergun, Funda, Sahinalp, S Cenk

“…Abstract Motivation Recent advances in single-cell sequencing (SCS) offer an unprecedented insight into tumor emergence and evolution. Principled approaches to…”
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Fast intratumor heterogeneity inference from single-cell sequencing data by Kızılkale, Can, Mehrabadi, Farid Rashidi, Azer, Erfan Sadeqi, Pérez-Guijarro, Eva, Marie, Kerrie L, Lee, Maxwell P, Day, Chi-Ping, Merlino, Glenn, Ergün, Funda, Buluç, Aydın, Sahinalp, S Cenk, Malikić, Salem

“…We introduce HUNTRESS, a computational method for mutational intratumor heterogeneity inference from noisy genotype matrices derived from single-cell…”
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PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data by Malikic, Salem, Mehrabadi, Farid Rashidi, Ciccolella, Simone, Rahman, Md Khaledur, Ricketts, Camir, Haghshenas, Ehsan, Seidman, Daniel, Hach, Faraz, Hajirasouliha, Iman, Sahinalp, S Cenk

“…Available computational methods for tumor phylogeny inference via single-cell sequencing (SCS) data typically aim to identify the most likely satisfying the…”
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Studying the History of Tumor Evolution from Single-Cell Sequencing Data by Exploring the Space of Binary Matrices by Malikić, Salem, Mehrabadi, Farid Rashidi, Azer, Erfan Sadeqi, Ebrahimabadi, Mohammad Haghir, Sahinalp, Suleyman Cenk

“…Single-cell sequencing (SCS) data have great potential in reconstructing the evolutionary history of tumors. Rapid advances in SCS technology in the past…”
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Abstract LB019: Trisicell: Scalable Tumor Phylogeny Reconstruction and Validation Reveals Developmental Origin and Therapeutic Impact of Intratumoral Heterogeneity by Mehrabadi, Farid Rashidi, Malikić, Salem, Marie, Kerrie L., Pérez-Guijarro, Eva, Azer, Erfan Sadeqi, Yang, Howard H., Kızılkale, Can, Gruen, Charli, Liu, Huaitian, Marcelus, Christina, Buluç, Aydın, Ergün, Funda, Lee, Maxwell P., Merlino, Glenn, Day, Chi-Ping, Sahinalp, S. Cenk

“…Abstract Emerging sets of single-cell sequencing data makes it appealing to apply existing tumor phylogeny reconstruction methods to analyze associated…”
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Scalable Tumor Phylogeny Inference and Validation from Single-Cell RNA or DNA Data by Rashidi Mehrabadi, Farid

“…Cancer is an evolutionary disease that is shaped by mutations and selection. Cancer progression often results in the emergence of distinct tumor cell…”
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Abstract 6924: Structural variant dynamics in melanoma: Unraveling tumor heterogeneity and evolution by Cui, Xiwen, Keskus, Ayse G., Mehrabadi, Farid R., Malikic, Salem, Kolmogorov, Mikhail, Day, Chi-Ping, Merlino, Glenn, Sahinalp, S. Cenk

“…Abstract Melanoma is characterized by significant intratumoral heterogeneity and complex evolutionary dynamics. This diversity in genomic alterations leads to…”
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A study on prediction of user's tendency toward purchases in websites based on behavior models by Gohari Boroujerdi, Emad, Mehri, Soroush, Sadeghi Garmaroudi, Saeed, Pezeshki, Mohammad, Rashidi Mehrabadi, Farid, Malakouti, SeyyedSalim, Khadivi, Shahram

“…Nowadays customers would rather buy their needs online than visiting a retail store because of many reasons such as saving time. Therefore, in order to…”
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Abstract 127: Single-cell methylation sequencing data reveals succinct metastatic migration histories and tumor progression models by Li, Xuan C., Liu, Yuelin, Mehrabadi, Farid Rashidi, Schäffer, Alejandro A., Pratt, Drew, Crawford, David R., Malikić, Salem, Molloy, Erin K., Gopalan, Vishaka, Mount, Stephen M., Ruppin, Eytan, Aldape, Kenneth, Sahinalp, S. Cenk

“…Abstract Recent studies exploring the impact of methylation in tumor evolution suggest that while the methylation status of many of the CpG sites are preserved…”
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