Search Results - "Mehra, Reena"
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Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (20-07-2021)“…Obstructive sleep apnea (OSA) is characterized by recurrent complete and partial upper airway obstructive events, resulting in intermittent hypoxemia,…”
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Metrics of sleep apnea severity: beyond the apnea-hypopnea index
Published in Sleep (New York, N.Y.) (01-07-2021)“…Abstract Obstructive sleep apnea (OSA) is thought to affect almost 1 billion people worldwide. OSA has well established cardiovascular and neurocognitive…”
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Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline
Published in Journal of clinical sleep medicine (15-03-2017)“…This guideline establishes clinical practice recommendations for the diagnosis of obstructive sleep apnea (OSA) in adults and is intended for use in…”
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CPAP versus Oxygen in Obstructive Sleep Apnea
Published in The New England journal of medicine (12-06-2014)“…In patients with obstructive sleep apnea, continuous positive airway pressure produced a small reduction in 24-hour mean arterial pressure; nocturnal…”
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A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19
Published in PLoS biology (01-11-2020)“…The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to unprecedented…”
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Sleep-Disordered Breathing and Cardiac Arrhythmias in Adults: Mechanistic Insights and Clinical Implications: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (30-08-2022)“…Sleep-disordered breathing (SDB), characterized by specific underlying physiological mechanisms, comprises obstructive and central pathophysiology, affects…”
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Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
Published in Alzheimer's research & therapy (09-06-2021)“…Dementia-like cognitive impairment is an increasingly reported complication of SARS-CoV-2 infection. However, the underlying mechanisms responsible for this…”
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Sleep duration and biomarkers of inflammation
Published in Sleep (New York, N.Y.) (01-02-2009)“…Extremes of sleep duration have been associated with adverse health outcomes. The mechanism is unclear but may be related to increased inflammation. We sought…”
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Machine learning polysomnographically-derived electroencephalography biomarkers predictive of epworth sleepiness scale
Published in Scientific reports (05-06-2023)“…Excessive daytime sleepiness (EDS) causes difficulty in concentrating and continuous fatigue during the day. In the clinical setting, the assessment and…”
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Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry
Published in The European respiratory journal (01-01-2019)“…Upper airway stimulation (UAS) has been shown to reduce severity of obstructive sleep apnoea. The aim of this study was to identify predictors of UAS therapy…”
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Triggering of Nocturnal Arrhythmias by Sleep-Disordered Breathing Events
Published in Journal of the American College of Cardiology (03-11-2009)“…Objectives This study sought to evaluate respiratory disturbances as potential triggers for arrhythmia in patients with sleep-disordered breathing (SDB)…”
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Impact of the COVID-19 Pandemic on Healthcare Workers’ Risk of Infection and Outcomes in a Large, Integrated Health System
Published in Journal of general internal medicine : JGIM (01-11-2020)“…Background Understanding the impact of the COVID-19 pandemic on healthcare workers (HCW) is crucial. Objective Utilizing a health system COVID-19 research…”
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Philips Respironics Recall of Positive Airway Pressure and Noninvasive Ventilation Devices: A Brief Statement to Inform Response Efforts and Identify Key Steps Forward
Published in American journal of respiratory and critical care medicine (15-10-2021)“…On June 14, 2021, Philips Respironics issued a voluntary recall notification in the United States and a field safety notice internationally of the vast…”
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Central Sleep-disordered Breathing Predicts Incident Atrial Fibrillation in Older Men
Published in American journal of respiratory and critical care medicine (01-04-2016)“…Although research supports a sleep-disordered breathing and atrial fibrillation association, prospective data examining sleep-disordered breathing predicting…”
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Author Correction: Machine learning polysomnographically-derived electroencephalography biomarkers predictive of epworth sleepiness scale
Published in Scientific reports (30-06-2023)Get full text
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Reducing Coronary Heart Disease Risk Through Treatment of Insomnia Using Web-Based Cognitive Behavioral Therapy for Insomnia: A Methodological Approach
Published in Behavioral sleep medicine (03-05-2020)“…Objective: Observational data demonstrate increased risk of recurrent acute coronary syndrome in patients with comorbid insomnia. We conducted a pragmatic…”
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Upper Airway Stimulation vs Positive Airway Pressure Impact on BP and Sleepiness Symptoms in OSA
Published in Chest (01-01-2020)“…Positive airway pressure (PAP) and upper airway stimulation (UAS) are approved OSA treatment options. Although the effect of PAP on improvement in BP and…”
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A Paradigm Shift in the Treatment of Central Sleep Apnea in Heart Failure
Published in Chest (01-10-2015)Get full text
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Overview of Common Sleep Disorders and Intersection with Dermatologic Conditions
Published in International journal of molecular sciences (30-04-2016)“…Sleep disorders are very common, often under-recognized and therefore undertreated, are associated with a myriad of medical conditions and could lead to…”
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Obstructive and Central Sleep Apnea and the Risk of Incident Atrial Fibrillation in a Community Cohort of Men and Women
Published in Journal of the American Heart Association (01-07-2017)“…Background Previous studies have documented a high prevalence of atrial fibrillation (AF) in individuals with obstructive sleep apnea (OSA). Central sleep…”
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