Search Results - "Mehn, D."
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Measuring particle size distribution and mass concentration of nanoplastics and microplastics: addressing some analytical challenges in the sub-micron size range
Published in Journal of colloid and interface science (15-04-2021)“…[Display omitted] The implementation of the proposal from the European Chemical Agency (ECHA) to restrict the use of nanoplastics (NP) and microplastics (MP)…”
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Physical characterization of liposomal drug formulations using multi-detector asymmetrical-flow field flow fractionation
Published in Journal of controlled release (10-04-2020)“…Liposomal formulations for the treatment of cancer and other diseases are the most common form of nanotechnology enabled pharmaceuticals (NEPs) submitted for…”
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Asymmetric-flow field-flow fractionation for measuring particle size, drug loading and (in)stability of nanopharmaceuticals. The joint view of European Union Nanomedicine Characterization Laboratory and National Cancer Institute - Nanotechnology Characterization Laboratory
Published in Journal of Chromatography A (04-01-2021)“…•Multi-detector AF4 for characterization of nanomedicines is reviewed•The development of high quality Standard Operating Procedures is presented•The…”
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Larger or more? Nanoparticle characterisation methods for recognition of dimers
Published in RSC advances (01-01-2017)“…Our article dissects the problem of understanding the origin of size heterogeneity in polydispersed nanoparticle samples. A commercially available multimodal…”
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Label-free imaging and identification of typical cells of acute myeloid leukaemia and myelodysplastic syndrome by Raman microspectroscopy
Published in Analyst (London) (21-02-2015)“…In clinical practice, the diagnosis and classification of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) start from the manual examination of…”
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Niosomal approach to brain delivery: Development, characterization and in vitro toxicological studies
Published in International journal of pharmaceutics (25-09-2016)“…[Display omitted] The majority of active agents do not readily permeate into brain due to the presence of the blood-brain barrier and blood-cerebrospinal fluid…”
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Developmental stage dependent neural stem cells sensitivity to methylmercury chloride on different biofunctional surfaces
Published in Toxicology in vitro (01-02-2014)“…•Vulnerability of HUCB-NSC to MeHg is developmentally related and cell type specific.•Cell type specific response of HUCB-NSC to MeHg vary on different…”
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Calcein assay: a high-throughput method to assess P-gp inhibition
Published in Xenobiotica (01-08-2011)“…Transporter mediated drug-drug interactions (tDDI) mediated by ABCB1 have been shown to be clinically relevant. Hence, the assessment of the ABCB1 tDDI…”
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Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2
Published in The Journal of pharmacology and experimental therapeutics (01-06-2007)“…ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of…”
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Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
Published in Nature (London) (20-05-2021)“…Neutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein are among the most promising approaches against COVID-19…”
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Optimization of CCVD synthesis conditions for single-wall carbon nanotubes by statistical design of experiments (DoE)
Published in Carbon (New York) (01-11-2005)“…We report the successful optimization of single-wall carbon nanotube (SWCNT) synthesis by catalytic chemical vapor deposition (CCVD) on FeMo/MgO catalyst using…”
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Functionalization of single-walled carbon nanotubes by using alkyl-halides
Published in Carbon (New York) (2005)“…In this paper we demonstrate the functionalization of single-walled carbon nanotubes prepared by chemical vapor deposition. The chosen functionalization agents…”
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Spherical mesoporous MCM-41 materials containing transition metals: synthesis and characterization
Published in Applied catalysis. A, General (28-09-2004)“…Transition metal containing spherical MCM-41 silicates were prepared and characterized by transmission electron microscopy (TEM), XRD, BET, TPR and IR…”
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Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein
Published in Science immunology (31-03-2023)“…Emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants diminishes the efficacy of vaccines and antiviral monoclonal antibodies…”
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On the growth mechanism of single-walled carbon nanotubes by catalytic carbon vapor deposition on supported metal catalysts
Published in Journal of nanoscience and nanotechnology (01-04-2004)“…A comprehensive kinetic study was performed to throw light on the formation mechanism of single walled carbon nanotubes (SWNTs) in chemical vapor deposition…”
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BSEP inhibition – In vitro screens to assess cholestatic potential of drugs
Published in Toxicology in vitro (01-12-2012)“…► The function of BSEP is to eliminate bile acids from hepatocyte into the bile. ► Drugs can cause drug induced liver injury (DILI) via several different and…”
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Immobilised gold nanostars in a paper-based test system for surface-enhanced Raman spectroscopy
Published in Vibrational spectroscopy (01-09-2013)“…Paper-based SERS active substrates were prepared adsorbing spherical and star-shaped gold nanoparticles on a standard filter paper support. Besides the…”
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End morphology of ball milled carbon nanotubes
Published in Carbon (New York) (2004)“…Multi-walled carbon nanotubes have been shortened by ball milling under ambient conditions. Detailed high-resolution TEM studies of the carbon nanotube ends…”
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Human monoclonal antibodies to the spike subdomain 1 neutralize SARS-CoV-2 and its variants of concern
Published in SWISS MEDICAL WEEKLY (2022)Get full text
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