Search Results - "Mehmet Berkoz"
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1
Noscapine Down-Regulates LPS-Induced Neuroinflammation in BV-2 Microglia Cells via Modulation of MAPK and NF-κB Signaling Pathways
Published in Neurochemical journal (01-09-2024)“…Noscapine is widely used to prevent stroke, glioblastoma, and anxiety. The aim of this study was to investigate the anti-neuroinflammatory activity and…”
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2
Protective roles of some natural and synthetic aromatase inhibitors in testicular insufficiency caused by Bisphenol A exposure
Published in International journal of environmental health research (02-06-2024)“…In our study, the protective role of synthetic aromatase inhibitors anastrozole (ANS), letrozole (LTZ) and exemestane (EXM) and natural aromatase inhibitors…”
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3
Boswellic Acid and Betulinic Acid Pre-treatments Can Prevent the Nephrotoxicity Caused by Cyclophosphamide Induction
Published in Doklady. Biochemistry and biophysics (01-08-2024)“…Cyclophosphamide (CYP) is a chemotherapeutic drug used to treat various cancers. However, its clinical use is limited due to severe organ damage, particularly…”
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4
Protective Role of Myricetin and Fisetin Against Nephrotoxicity Caused by Lead Acetate Exposure through Up-regulation of Nrf2/HO-1 Signalling Pathway
Published in Biological trace element research (01-09-2024)“…The effect of various flavonoids against oxidative stress and inflammation caused by lead exposure has been investigated. However, the protective effects of…”
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5
Hepatoprotective potentials of Usnea longissima Ach. and Xanthoparmelia somloensis (Gyelnik) Hale extracts in ethanol-induced liver injury
Published in Drug and chemical toxicology (New York, N.Y. 1978) (25-09-2024)“…In our study, the antioxidant and anti-inflammatory effects of different lichen applications were investigated in rats using an experimental ethanol toxicity…”
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The Toxicological Risk Assessment of Lead and Cadmium in Valeriana officinalis L., radix (Valerian root) as Herbal Medicinal Product for the Relief of Mild Nervous Tension and Sleep Disorders Available in Polish Pharmacies
Published in Biological trace element research (01-02-2022)“…Studies related to the toxicological risk assessment (TRA) of heavy metal impurities (HMIs) in pharmaceuticals are an important issue but there is a lack of…”
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The Toxicological Risk Assessment of Cu, Mn, and Zn as Essential Elemental Impurities in Herbal Medicinal Products with Valerian Root (Valeriana officinalis L., radix) Available in Polish Pharmacies
Published in Biological trace element research (01-04-2022)“…The toxicological risk assessment (TRA) of elemental impurities (EI) in especially herbal medicinal products (HMP) is a significant challenge for…”
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8
Effects of fisetin on ethanol-induced rewarding properties in mice
Published in The American journal of drug and alcohol abuse (02-01-2024)“…Alcohol use disorder (AUD) is a chronic relapsing disorder associated with compulsive drinking of alcohol. Natural flavonoid fisetin affects a variety of…”
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9
Prophylactic effect of myricetin and apigenin against lipopolysaccharide-induced acute liver injury
Published in Molecular biology reports (01-09-2021)“…Background Liver has an important role in the initiation and progression of multiple organ failure that occurs in sepsis. Many natural active substances can be…”
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10
Punicalagin induces apoptosis in A549 cell line through mitochondria-mediated pathway
Published in General physiology and biophysics (01-11-2020)“…Lung cancer is the most common cause of cancer-related deaths worldwide. Punicalagin is an ellagitannin mostly found in pomegranate husk and shows very strong…”
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Protective role of resveratrol and apigenin against toxic effects of bisphenol a in rat salivary gland
Published in Drug and chemical toxicology (New York, N.Y. 1978) (02-01-2023)“…The aim of this study was to investigate the cellular changes caused by Bisphenol A (BPA) exposure in salivary gland cells and to examine the protective role…”
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12
Investigation of protective roles of myricetin and quercetin against nephrotoxicity caused by malathion intoxication in rats
Published in Medicine science (01-06-2023)“…In this study, the protective roles of myricetin (MYC) and quercetin (QRS) against nephrotoxicity caused by malathion (MLT) intoxication were investigated. A…”
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13
The Health Risk Assessment of Essential Elemental Impurities (Cu, Mn and Zn) Through the Dermal Exposure of Herbal Ointment Extracted from Marjoram Herb (Majoranae herbae extractum)
Published in Biological trace element research (01-04-2022)“…Essential elements like Cu, Mn and Zn are extremely important for herbs’ growth and physiological functions; however, from a toxicological point of view, the…”
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The Toxicological Risk Assessment of Dermal Exposure of Patients Exposed to Nickel and Chromium due to Application of Ointments with Marjoram Herb Extract (Majoranae Herbae Extractum) Available in Polish Pharmacies
Published in Biological trace element research (01-04-2022)“…For elemental impurities that have been studied for transcutaneous absorption, the available data are rarely suitable for proper toxicological risk assessment…”
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15
Prophylactic effect of Biochanin A in lipopolysaccharide-stimulated BV2 microglial cells
Published in Immunopharmacology and immunotoxicology (15-07-2020)“…Aim/Purpose of the study:Inhibition of microglial activation using phytochemicals may be a potential candidate for the prevention of neurodegenerative diseases…”
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16
Strontium ranelate treatment improves oxidative damage in osteoporotic rat model
Published in Pharmacological reports (2012)“…Osteoporosis is the most common skeletal disorder and is considered a risk of fracture. Most medication used for the treatment of osteoporosis is…”
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Protective effect of myricetin, apigenin, and hesperidin pretreatments on cyclophosphamide-induced immunosuppression
Published in Immunopharmacology and immunotoxicology (04-05-2021)“…Aim: Major side effects of cyclophosphamide administration are immunosuppression and myelosuppression. The immunomodulatory effects of plant bioactive…”
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18
PAI-1 and tPA gene polymorphisms and susceptibility to chronic obstructive pulmonary disease in a sample of Turkish population
Published in Journal of the Pakistan Medical Association (01-12-2020)“…Abstract Objective: The aim of this study was to assess the influence of plasminogen activator inhibitor-1 (PAI-1) 4G/5G or tissue plasminogen activator (tPA)…”
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Correlation Between GSH-Px Pro198Leu, CAT-262C/T, MnSOD Ala16Val Gene Polymorphisms and Allergic Rhinitis
Published in İstanbul Medical Journal (01-08-2022)“…Introduction: In this study, we investigated the etiopathogenesis of allergic rhinitis by analyzing the polymorphisms including GPx-1 Pro198Leu, CAT-262 C/T,…”
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20
Determination of Genotoxic Effects of Hookah Smoking by Micronucleus and Chromosome Aberration Methods
Published in Medical science monitor (21-11-2016)“…BACKGROUND Use of a hookah (a type of water pipe) is a traditional way of smoking tobacco, particularly in the Middle East. In Turkey, its popularity has been…”
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