Search Results - "Mehlman, Tevie"

The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products by Garb, Jeremy, Amitai, Gil, Lu, Allen, Ofir, Gal, Brandis, Alexander, Mehlman, Tevie, Kranzusch, Philip J, Sorek, Rotem

“…Sterile alpha and TIR motif-containing 1 (SARM1) is a protein involved in programmed death of injured axons. Following axon injury or a drug-induced insult,…”
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LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea by Goldsmith, Moshe, Avram, Liat, Brandis, Alexander, Mehlman, Tevie, Ben-Dor, Shifra, Peleg, Yoav, Ben-Zeev, Efrat, Barbole, Ranjit S., Reich, Ziv

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The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta by Stroganov, Sima, Harris, Talia, Fellus-Alyagor, Liat, Ben Moyal, Lital, Plitman Mayo, Romina, Golani, Ofra, Hirsch, Dana, Ben-Dor, Shifra, Brandis, Alexander, Mehlman, Tevie, Kovo, Michal, Biron-Shental, Tal, Dekel, Nava, Neeman, Michal

“…Fetal growth restriction (FGR) is a pregnancy complication in which a newborn fails to achieve its growth potential, increasing the risk of perinatal morbidity…”
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N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer’s disease mouse model by Suzzi, Stefano, Croese, Tommaso, Ravid, Adi, Gold, Or, Clark, Abbe R., Medina, Sedi, Kitsberg, Daniel, Adam, Miriam, Vernon, Katherine A., Kohnert, Eva, Shapira, Inbar, Malitsky, Sergey, Itkin, Maxim, Brandis, Alexander, Mehlman, Tevie, Salame, Tomer M., Colaiuta, Sarah P., Cahalon, Liora, Slyper, Michal, Greka, Anna, Habib, Naomi, Schwartz, Michal

“…Systemic immunity supports lifelong brain function. Obesity posits a chronic burden on systemic immunity. Independently, obesity was shown as a risk factor for…”
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The dynamic disulphide relay of quiescin sulphydryl oxidase by Alon, Assaf, Grossman, Iris, Gat, Yair, Kodali, Vamsi K., DiMaio, Frank, Mehlman, Tevie, Haran, Gilad, Baker, David, Thorpe, Colin, Fass, Deborah

“…The X-ray crystal structures of trypanosome and mammalian quiescin sulphydryl oxidase are determined; these structures and follow-up biochemical studies show…”
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ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus by Lerner, Shaul, Anderzhanova, Elmira, Verbitsky, Sima, Eilam, Raya, Kuperman, Yael, Tsoory, Michael, Kuznetsov, Yuri, Brandis, Alexander, Mehlman, Tevie, Mazkereth, Ram, Alber, Fabienne Dietrich, Babikian, Talin, Bender, Heidi, Boys, Christopher, Breiger, David, Buerger, Corinna, Burgard, Peter, Nguyen-Driver, Mina, Goodlett, Benjamin, Kerr, Elizabeth, Krueger, Casey, Mamak, Eva, Sanz, Jacqueline H., Schwartz, David, Caudle, Susan, Stefanos, Arianna, Tangen, Rachel, Walter, Magdalena, Waisbren, Susan, Wilkening, Greta, McCarter, Robert, Segal, Menahem, Nagamani, Sandesh C.S., Chen, Alon, Erez, Ayelet

“…Patients with germline mutations in the urea-cycle enzyme argininosuccinate lyase (ASL) are at risk for developing neurobehavioral and cognitive deficits. We…”
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Protocol for studying microbiome impact on host energy and reproduction in Drosophila by Gnainsky, Yulia, Itkin, Maxim, Mehlman, Tevie, Brandis, Alexander, Malitsky, Sergey, Soen, Yoav

“…Drosophila gut microbiome in flies has been shown to have a systemic influence on energy production by the host and the energetic investment in growth and…”
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β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice by Panayotis, Nicolas, Freund, Philip A., Marvaldi, Letizia, Shalit, Tali, Brandis, Alexander, Mehlman, Tevie, Tsoory, Michael M., Fainzilber, Mike

“…Anxiety and stress-related conditions represent a significant health burden in modern society. Unfortunately, most anxiolytic drugs are prone to side effects,…”
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Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase by Limor-Waisberg, Keren, Alon, Assaf, Mehlman, Tevie, Fass, Deborah

“…► We demonstrate the expression of A. thaliana QSOX in a recombinant bacterial system. ► Recombinant A. thaliana QSOX shows robust sulfhydryl oxidase activity…”
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Gender and sexual behavior modulate the composition of serum lipocalins in Nile tilapia (Oreochromis niloticus) by Shirak, Andrey, Reicher, Shay, Uliel, Shai, Mehlman, Tevie, Shainskaya, Alla, Ron, Micha, Seroussi, Eyal

“…In tilapia species, plasma lipoproteins with high electrophoretic mobility function in intra- and intergender communication. Blood samples taken at onset and…”
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Steps in reductive activation of the disulfide‐generating enzyme Ero1p by Heldman, Nimrod, Vonshak, Ohad, Sevier, Carolyn S., Vitu, Elvira, Mehlman, Tevie, Fass, Deborah

“…Ero1p is the primary catalyst of disulfide bond formation in the yeast endoplasmic reticulum (ER). Ero1p contains a pair of essential disulfide bonds that…”
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A conserved family of immune effectors cleaves cellular ATP upon viral infection by Rousset, Francois, Yirmiya, Erez, Nesher, Shahar, Brandis, Alexander, Mehlman, Tevie, Itkin, Maxim, Malitsky, Sergey, Millman, Adi, Melamed, Sarah, Sorek, Rotem

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Cyclic CMP and cyclic UMP mediate bacterial immunity against phages by Tal, Nitzan, Morehouse, Benjamin R., Millman, Adi, Stokar-Avihail, Avigail, Avraham, Carmel, Fedorenko, Taya, Yirmiya, Erez, Herbst, Ehud, Brandis, Alexander, Mehlman, Tevie, Oppenheimer-Shaanan, Yaara, Keszei, Alexander F.A., Shao, Sichen, Amitai, Gil, Kranzusch, Philip J., Sorek, Rotem

“…The cyclic pyrimidines 3′,5′-cyclic cytidine monophosphate (cCMP) and 3′,5′-cyclic uridine monophosphate (cUMP) have been reported in multiple organisms and…”
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Potential roles of gut microbiome and metabolites in modulating ALS in mice by Blacher, Eran, Bashiardes, Stavros, Shapiro, Hagit, Rothschild, Daphna, Mor, Uria, Dori-Bachash, Mally, Kleimeyer, Christian, Moresi, Claudia, Harnik, Yotam, Zur, Maya, Zabari, Michal, Brik, Rotem Ben-Zeev, Kviatcovsky, Denise, Zmora, Niv, Cohen, Yotam, Bar, Noam, Levi, Izhak, Amar, Nira, Mehlman, Tevie, Brandis, Alexander, Biton, Inbal, Kuperman, Yael, Tsoory, Michael, Alfahel, Leenor, Harmelin, Alon, Schwartz, Michal, Israelson, Adrian, Arike, Liisa, Johansson, Malin E. V., Hansson, Gunnar C., Gotkine, Marc, Segal, Eran, Elinav, Eran

“…Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder, in which the clinical manifestations may be influenced by genetic and unknown…”
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A Genetically Engineered Reporter System Designed for 2H-MRI Allows Quantitative In Vivo Mapping of Transgene Expression by Allouche-Arnon, Hyla, Montrazi, Elton T, Subramani, Balamurugan, Fisler, Michal, Spigel, Inbal, Frydman, Lucio, Mehlman, Tevie, Brandis, Alexander, Harris, Talia, Bar-Shir, Amnon

“…The ability to obtain quantitative spatial information on subcellular processes of deep tissues in vivo has been a long-standing challenge for molecular…”
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A Genetically Engineered Reporter System Designed for 2 H-MRI Allows Quantitative In Vivo Mapping of Transgene Expression by Allouche-Arnon, Hyla, Montrazi, Elton T., Subramani, Balamurugan, Fisler, Michal, Spigel, Inbal, Frydman, Lucio, Mehlman, Tevie, Brandis, Alexander, Harris, Talia, Bar-Shir, Amnon

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Systemic Regulation of Host Energy and Oogenesis by Microbiome-Derived Mitochondrial Coenzymes by Gnainsky, Yulia, Zfanya, Nofar, Elgart, Michael, Omri, Eman, Brandis, Alexander, Mehlman, Tevie, Itkin, Maxim, Malitsky, Sergey, Adamski, Jerzy, Soen, Yoav

“…Gut microbiota have been shown to promote oogenesis and fecundity, but the mechanistic basis of remote influence on oogenesis remained unknown. Here, we report…”
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Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression by Allouche-Arnon, Hyla, Khersonsky, Olga, Tirukoti, Nishanth D., Peleg, Yoav, Dym, Orly, Albeck, Shira, Brandis, Alexander, Mehlman, Tevie, Avram, Liat, Harris, Talia, Yadav, Nirbhay N., Fleishman, Sarel J., Bar-Shir, Amnon

“…Imaging of gene-expression patterns in live animals is difficult to achieve with fluorescent proteins because tissues are opaque to visible light. Imaging of…”
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Gut microbiota modulates weight gain in mice after discontinued smoke exposure by Fluhr, Leviel, Mor, Uria, Kolodziejczyk, Aleksandra A., Dori-Bachash, Mally, Leshem, Avner, Itav, Shlomik, Cohen, Yotam, Suez, Jotham, Zmora, Niv, Moresi, Claudia, Molina, Shahar, Ayalon, Niv, Valdés-Mas, Rafael, Hornstein, Shanni, Karbi, Hodaya, Kviatcovsky, Denise, Livne, Adi, Bukimer, Aurelie, Eliyahu-Miller, Shimrit, Metz, Alona, Brandis, Alexander, Mehlman, Tevie, Kuperman, Yael, Tsoory, Michael, Stettner, Noa, Harmelin, Alon, Shapiro, Hagit, Elinav, Eran

“…Cigarette smoking constitutes a leading global cause of morbidity and preventable death 1 , and most active smokers report a desire or recent attempt to quit 2…”
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Cryo-EM structure of the RADAR supramolecular anti-phage defense complex by Duncan-Lowey, Brianna, Tal, Nitzan, Johnson, Alex G., Rawson, Shaun, Mayer, Megan L., Doron, Shany, Millman, Adi, Melamed, Sarah, Fedorenko, Taya, Kacen, Assaf, Brandis, Alexander, Mehlman, Tevie, Amitai, Gil, Sorek, Rotem, Kranzusch, Philip J.

“…RADAR is a two-protein bacterial defense system that was reported to defend against phage by “editing” messenger RNA. Here, we determine cryo-EM structures of…”
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