Search Results - "Mehlhorn, Alexander T."

Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma by Niemeyer, Philipp, Fechner, Katharina, Milz, Stefan, Richter, Wiltrud, Suedkamp, Norbert P, Mehlhorn, Alexander T, Pearce, Simon, Kasten, Philip

“…Abstract Aim of the present study was to compare the osteogenic potential of bone marrow derived mesenchymal stem cells (BMSC) and adipose-tissue derived stem…”
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Survival and neurologic outcome after traumatic out-of-hospital cardiopulmonary arrest in a pediatric and adult population: a systematic review by Zwingmann, Jörn, Mehlhorn, Alexander T, Hammer, Thorsten, Bayer, Jörg, Südkamp, Norbert P, Strohm, Peter C

“…This systematic review is focused on the in-hospital mortality and neurological outcome of survivors after prehospital resuscitation following trauma. Data…”
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Gastrocnemius Recession Leads to Increased Ankle Motion and Improved Patient Satisfaction After 2 Years of Follow-Up by Holtmann, Julia Alessandra, MD, Südkamp, Norbert P., PhD, Schmal, Hagen, MD, Mehlhorn, Alexander T., MD

“…Abstract The isolated gastrocnemius contracture present in neurologic healthy patients results in a significant limitation of ankle dorsiflexion causing…”
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Xenogenic transplantation of human mesenchymal stem cells in a critical size defect of the sheep tibia for bone regeneration by Niemeyer, Philipp, Schönberger, Thomas S, Hahn, Joachim, Kasten, Philip, Fellenberg, Joerg, Suedkamp, Norbert, Mehlhorn, Alexander T, Milz, Stefan, Pearce, Simon

“…Mesenchymal stem cells (MSCs) represent an attractive cell population for the regeneration of mesenchymal tissues. Their special immunological characteristics…”
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Complication assessment and prevention strategies using midfoot fusion bolt for medial column stabilization in Charcot’s osteoarthropathy by Mehlhorn, Alexander T., MD, Walther, Markus, MD, Iblher, Niklas, MD, Südkamp, Norbert P., MD, Schmal, Hagen, MD

“…Highlights • The number of postoperative complications following stabilization of the neuroosteoarthropathic foot using midfoot fusion bolt is high, but can be…”
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Classification and Outcome of Fracture-Dislocation of the Cuneiform Bones by Mehlhorn, Alexander T., MD, Schmal, Hagen, MD, Legrand, Maria Anna, MD, Südkamp, Norbert P., MD, Strohm, Peter C., MD

“…Abstract Fractures and dislocations of the cuneiform bones are rare injuries to the midtarsal foot. The injury severity is often unclear, and the prognostic…”
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Histopathological assessment of a two-stage reconstructive procedure of the infected Charcot foot by Mehlhorn, Alexander T., Illgner, Ulrich, Lemperle, Stefan, Hoerterer, Hubert, Krenn, Veith, Walther, Markus

“…Introduction Charcot neuropathic osteoarthropathy (CN) can be complicated by osteomyelitis (OM). Surgery is a standard procedure to treat OM including…”
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Association between expression of the bone morphogenetic proteins 2 and 7 in the repair of circumscribed cartilage lesions with clinical outcome by Schmal, Hagen, Niemeyer, Philipp, Zwingmann, Jörn, Stoffel, Fabian, Südkamp, Norbert P, Mehlhorn, Alexander T

“…Although there is much known about the role of BMPs in cartilage metabolism reliable data about the in vivo regulation in natural and surgically induced…”
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Immunohistological Localization of BMP-2, BMP-7, and Their Receptors in Knee Joints with Focal Cartilage Lesions by Schmal, Hagen, Mehlhorn, Alexander T., Pilz, Ingo H., Dovi-Akue, David, Kirchhoff, Christina, Südkamp, Norbert P., Gerlach, Ulrike, Lohrmann, Christian, Niemeyer, Philipp

“…Introduction. Although it is well known that BMP-2 and BMP-7 play significant roles in cartilage metabolism, data about intra-articular expression and…”
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Development and characterization of a spheroidal coculture model of endothelial cells and fibroblasts for improving angiogenesis in tissue engineering by Wenger, Andreas, Kowalewski, Nadja, Stahl, Andreas, Mehlhorn, Alexander T, Schmal, Hagen, Stark, G Bjorn, Finkenzeller, Gunter

“…Neovascularization is a critical step in tissue engineering applications since implantation of voluminous grafts without sufficient vascularity results in…”
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Dynamic plantar pressure distribution, strength capacity and postural control after Lisfranc fracture-dislocation by Mehlhorn, Alexander T, Walther, Markus, Yilmaz, Tayfun, Gunst, Lennart, Hirschmüller, Anja, Südkamp, Norbert P, Schmal, Hagen

“…Highlights • A significant reduction in peak pressure under the midfoot was assessed. • The Force-Time Integral under the second tarsometatarsal joint was…”
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A high-profile thread with grit-blasted and acid-etched surface reduces loosening of medial column fusion bolt in instable Charcot foot by Mehlhorn, Alexander T., Ugland, Karl I., Hörterer, Hubert, Gottschalk, Oliver, Südkamp, Norbert, Walther, Markus

“…•Bony consolidation of fusion sites is improved using surface modified medial column fusion bolt in Charcot foot.•Despite an initial restoration of the foot…”
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Synovial cytokine expression in ankle osteoarthritis depends on age and stage by Schmal, Hagen, Henkelmann, Ralf, Mehlhorn, Alexander T., Reising, Kilian, Bode, Gerrit, Südkamp, Norbert P., Niemeyer, Philipp

“…Purpose Aim of the study was the analysis of cytokine expression in ankle osteoarthritis (OA) hypothesizing age-dependent regulation patterns. Methods…”
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Does inflammatory activity of Charcot foot affect successful corrective arthrodesis? by Mehlhorn, Alexander T, Illgner, Ulrich, Lemperle, Stefan, Huber, Verena, Hoerterer, Hubert, Gottschalk, Oliver, Legrand, Maria Anna, Krenn, Veit, Walther, Markus

“…Neuro-osteoarthropathy of the foot (CN) is divided into an active and inactive stage, with impact on the further treatment. The histopathological Charcot score…”
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Quantitative and functional impairment of pulmonary CD4+ CD25hi regulatory T cells in pediatric asthma by Hartl, Dominik, MD, Koller, Barbara, MD, Mehlhorn, Alexander T., MD, Reinhardt, Dietrich, MD, Nicolai, Thomas, MD, Schendel, Dolores J., PhD, Griese, Matthias, MD, Krauss-Etschmann, Susanne, MD

“…Background Asthma is characterized by a TH 2 immune response. CD4+ CD25hi regulatory T cells (Tregs) have been proposed to prevent allergic diseases through…”
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A new technique for seeding chondrocytes onto solvent-preserved human meniscus using the chemokinetic effect of recombinant human bone morphogenetic protein-2 by MINEHARA, Hiroaki, URABE, Ken, NARUSE, Kouji, MEHLHORN, Alexander T, UCHIDA, Kentaroo, SÜDKAMP, Norbert P, ITOMAN, Moritoshi

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Radiographic classification for fractures of the fifth metatarsal base by Mehlhorn, Alexander T., Zwingmann, Jörn, Hirschmüller, Anja, Südkamp, Norbert P., Schmal, Hagen

“…Objective Avulsion fractures of the fifth metatarsal base (MTB5) are common fore foot injuries. Based on a radiomorphometric analysis reflecting the risk for a…”
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Gastrocnemius recession leads to medial shift of gait line, impairment of muscle strength and improved dorsal extension in forefoot overload syndrome by Schmal, Hagen, Walther, Markus, Hirschmüller, Anja, Bunert, Nina, Südkamp, Norbert P, Mehlhorn, Alexander T

“…Highlights • After gastrocnemius recession (GR) plantarflexors are impaired about 40% at 6 weeks. • Plantarflexors regain power up to 90% at 24 weeks after GR…”
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Pain Perception in Knees With Circumscribed Cartilage Lesions Is Associated With Intra-articular IGF-1 Expression by Schmal, Hagen, Niemeyer, Philipp, Südkamp, Norbert P., Gerlach, Ulrike, Dovi-Akue, David, Mehlhorn, Alexander T.

“…Background: Circumscribed cartilage defects are considered as prearthritic lesions and lead to differential intra-articular cytokine expression. Mechanisms of…”
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Nanomechanics of human adipose-derived stem cells: small GTPases impact chondrogenic differentiation by Jungmann, Pia M, Mehlhorn, Alexander T, Schmal, Hagen, Schillers, Hermann, Oberleithner, Hans, Südkamp, Norbert P

“…Human adipose-derived stem cells (ASCs) show gene expression of chondrogenic markers after three-dimensional cultivation. However, hypertrophy and osteogenic…”
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