Search Results - "Meher, Jaya Gopal"
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Nanoemulsion: Concepts, development and applications in drug delivery
Published in Journal of controlled release (28-04-2017)“…Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O) or oil in water (O/W) droplets stabilized by an amphiphilic…”
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Engineered nanocrystal technology: In-vivo fate, targeting and applications in drug delivery
Published in Journal of controlled release (10-06-2014)“…Formulation of nanocrystals is a robust approach which can improve delivery of poorly water soluble drugs, a challenge pharmaceutical industry has been facing…”
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3
Targeting tumor associated macrophages (TAMs) via nanocarriers
Published in Journal of controlled release (28-05-2017)“…Recruitment of inflammatory cells to tumor has been well documented, with the most frequent inhabitants being macrophages termed as tumor associated…”
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4
Targeting of gastrointestinal tract for amended delivery of protein/peptide therapeutics: Strategies and industrial perspectives
Published in Journal of controlled release (28-12-2014)“…Delivery of proteins/peptides to the gastrointestinal (GI) tract via peroral/oral route involves tremendous challenges due to unfavorable environmental…”
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Development and characterization of cellulose–polymethacrylate mucoadhesive film for buccal delivery of carvedilol
Published in Carbohydrate polymers (01-07-2013)“…•Carvedilol mucoadhesive films developed with cellulose and polymethacrylate polymer.•Film exhibited better mucoadhesive/film strength, swelling index and drug…”
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Perspectives of nanoemulsion assisted oral delivery of docetaxel for improved chemotherapy of cancer
Published in Drug delivery (12-02-2016)“…Nanoemulsions (NE) are one of the robust delivery tools for drugs due to their higher stability and efficacy. The purpose of present investigation is to…”
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Dendrimer-entrapped gold nanoparticles as promising nanocarriers for anticancer therapeutics and imaging
Published in Progress in materials science (01-06-2019)“…Theranostic nanotherapeutic strategy has been widely emphasized now a day to develop next-generation nanomedicine. Dendrimer-entrapped gold nanoparticles…”
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Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin
Published in International journal of biological macromolecules (01-02-2019)“…Immunotherapeutic nanoparticles (NPs) could be a viable option for delivering cytotoxic agents in a manner which suppresses their toxic manifestations…”
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Subcutaneously Administered Ultrafine PLGA Nanoparticles Containing Doxycycline Hydrochloride Target Lymphatic Filarial Parasites
Published in Molecular pharmaceutics (06-06-2016)“…Systemic chemotherapeutic targeting of filarial parasites is unfocused due to their deep seated location in lymphatic vessels. This warrants a prolonged dosing…”
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Immunotherapeutic vitamin E nanoemulsion synergies the antiproliferative activity of paclitaxel in breast cancer cells via modulating Th1 and Th2 immune response
Published in Journal of controlled release (28-12-2014)“…Paclitaxel (PTX) is used as first line treatment for metastatic breast cancer but the relief comes at a heavy cost in terms of accompanying adverse effects…”
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Chitosan coated PluronicF127 micelles for effective delivery of Amphotericin B in experimental visceral leishmaniasis
Published in International journal of biological macromolecules (01-12-2017)“…The goal of study was to develop micellar formulation of Amphotericin B (AmB) to improve its antileishmanial efficacy. AmB loaded pluronic F127 (PF 127)…”
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Paclitaxel-Loaded Colloidal Silica and TPGS-Based Solid Self-Emulsifying System Interferes Akt/mTOR Pathway in MDA-MB-231 and Demonstrates Anti-tumor Effect in Syngeneic Mammary Tumors
Published in AAPS PharmSciTech (09-11-2020)“…A solid self-emulsifying drug delivery system (SEDDS) of paclitaxel (PTX) was developed that could enhance its oral bioavailability and neutralize other…”
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13
Determination of required hydrophilic-lipophilic balance of citronella oil and development of stable cream formulation
Published in Drug development and industrial pharmacy (01-10-2013)“…Context: Citronella oil is reported to have excellent mosquito-repellent activity. To develop a stable cream formulation (emulsion), its hydrophilic-lipophilic…”
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Click Biotinylation of PLGA Template for Biotin Receptor Oriented Delivery of Doxorubicin Hydrochloride in 4T1 Cell-Induced Breast Cancer
Published in Molecular pharmaceutics (07-08-2017)“…PLGA was functionalized with PEG and biotin using click chemistry to generate a biotin receptor targeted copolymer (biotinylated–PEG-PLGA) which in turn was…”
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Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual ‘Chemoimmunotherapeutic’ Intervention in Breast Cancer
Published in Pharmaceutical research (01-09-2017)“…Objective To utilize nanoparticles produced by condensation of zymosan (an immunotherapeutic polysaccharide) with pegylated polyethylenimine (PEG-PEI) for dual…”
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Bridging small interfering RNA with giant therapeutic outcomes using nanometric liposomes
Published in Journal of controlled release (28-12-2015)“…The scope of RNAi based therapeutics is unquestionable. However, if we dissect the current trend of clinical trials for afore mentioned drug class, some stark…”
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Cellulose Buccoadhesive Film Bearing Glimepiride: Physicomechanical Characterization and Biophysics of Buccoadhesion
Published in AAPS PharmSciTech (01-08-2016)“…The present study aimed to develop buccoadhesive film of glimepiride with unique combination of polymers and to investigate its effect(s) on physicomechanical…”
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18
Nanosized complexation assemblies housed inside reverse micelles churn out monocytic delivery cores for bendamustine hydrochloride
Published in European journal of pharmaceutics and biopharmaceutics (01-04-2017)“…[Display omitted] We explore a plausible method of targeting bendamustine hydrochloride (BM) to circulatory monocytes by exploiting their intrinsic…”
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Enrichment, Development, and Assessment of Indian Basil Oil Based Antiseptic Cream Formulation Utilizing Hydrophilic-Lipophilic Balance Approach
Published in BioMed research international (01-01-2013)“…The present work was aimed to develop an antiseptic cream formulation of Indian basil oil utilizing hydrophilic-lipophilic balance approach. In order to…”
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Paclitaxel-loaded TPGS enriched self-emulsifying carrier causes apoptosis by modulating survivin expression and inhibits tumour growth in syngeneic mammary tumours
Published in Artificial cells, nanomedicine, and biotechnology (01-01-2018)“…Paclitaxel (PTX) in its commercial products exhibits adverse effects owing to excipients and also has poor oral bioavailability. Present work is directed…”
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