Search Results - "Mehdi, Syed J"

Mesenchymal stem cells gene signature in high‐risk myeloma bone marrow linked to suppression of distinct IGFBP2‐expressing small adipocytes by Mehdi, Syed J., Johnson, Sarah K., Epstein, Joshua, Zangari, Maurizio, Qu, Pingping, Hoering, Antje, Rhee, Frits, Schinke, Carolina, Thanendrarajan, Sharmilan, Barlogie, Bart, Davies, Faith E., Morgan, Gareth J., Yaccoby, Shmuel

“…Summary Recent studies suggest that multiple myeloma (MM) induces proliferation and expansion of bone marrow (BM) mesenchymal stem cells (MSCs), but others…”
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Gene Expression Comparison between Sézary Syndrome and Lymphocytic-Variant Hypereosinophilic Syndrome Refines Biomarkers for Sézary Syndrome by Moerman-Herzog, Andrea, Mehdi, Syed J, Wong, Henry K

“…Sézary syndrome (SS), an aggressive cutaneous T-cell lymphoma (CTCL) with poor prognosis, is characterized by the clinical hallmarks of circulating malignant T…”
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Growth and dormancy control of myeloma cells by mesenchymal stem cells by Mehdi, Syed J., Ghatak, Kalyan, Ling, Wen, Johnson, Sarah K., Epstein, Joshua, Nookaew, Intawat, Zangari, Maurizio, Schinke, Carolina, Thanendrarajan, Sharmilan, van Rhee, Frits, Yaccoby, Shmuel

“…Bone marrow mesenchymal stem cells (MSCs) may have contrasting impacts on the progression of multiple myeloma (MM). Priming normal MSCs, by culturing them with…”
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The Pattern of Mesenchymal Stem Cell Expression Is an Independent Marker of Outcome in Multiple Myeloma by Schinke, Carolina, Qu, Pingping, Mehdi, Syed J, Hoering, Antje, Epstein, Joshua, Johnson, Sarah K, van Rhee, Frits, Zangari, Maurizio, Thanendrarajan, Sharmilan, Barlogie, Bart, Davies, Faith E, Yaccoby, Shmuel, Morgan, Gareth J

“…Mesenchymal stem cells (MSC) are an essential component of the bone marrow microenvironment and have shown to support cancer evolution in multiple myeloma…”
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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling by Mehdi, Syed J, Moerman-Herzog, Andrea M, Wong, Henry K

“…Cutaneous T-cell lymphomas (CTCL) are derived from the transformation and uncontrolled proliferation of mature skin-homing T cells, and mycosis fungoides (MF)…”
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EDNRA-Expressing Mesenchymal Cells Are Expanded in Myeloma Interstitial Bone Marrow and Associated with Disease Progression by Ling, Wen, Johnson, Sarah K, Mehdi, Syed J, Alapat, Daisy V, Bauer, Michael, Zangari, Maurizio, Schinke, Carolina, Thanendrarajan, Sharmilan, van Rhee, Frits, Yaccoby, Shmuel

“…Multiple myeloma (MM) induces dysfunctional bone marrow (BM) mesenchymal cells and neoangiogenesis. Pericytes and smooth muscle cells (SMCs) could detach from…”
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Upregulated MicroRNA-21 Drives the Proliferation of Lymphatic Malformation Endothelial Cells by Inhibiting PDCD4 by Sun, Ravi W., Zhang, Haihong, Mehdi, Syed J., Richter, Gresham T., Bowman, Hayden H., Sifford, Jessica, Smith, Chelsea, Burnett, Alexander K., Layman, Alexander, Washam, Charity L., Byrum, Stephanie D., Bennett, James T., Jensen, Dana M., Dmyterko, Victoria, Perkins, Jonathan A., Shawber, Carrie J., Wu, June K., Strub, Graham M.

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The mTOR Component, Rictor, Is Regulated By the Microenvironment to Control Dormancy and Proliferative States in Myeloma Cells by Mehdi, Syed J., Johnson, Sarah K, Garg, Tarun K., Ashby, Cody, Zangari, Maurizio, Schinke, Carolina D., Thanendrarajan, Sharmilan, Epstein, Joshua, Walker, Brian A, van Rhee, Frits, Yaccoby, Shmuel

“…Introduction: Multiple myeloma (MM) cell dormancy and proliferative states, particularly in standard risk patients, are regulated by the BM niches and factors…”
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Mesenchymal Stem Cells Gene Signature in High-Risk Myeloma Bone Marrow Linked to Suppression of Distinct IGFBP2-Expressing Small Adipocytes by Mehdi, Syed J., Johnson, Sarah K, Epstein, Joshua, Zangari, Maurizio, Qu, Pingping, Hoering, Antje, van Rhee, Frits, Schinke, Carolina D., Thanendrarajan, Sharmilan, Davies, Faith E., Morgan, Gareth, Yaccoby, Shmuel

“…Introduction: Certain studies suggest that multiple myeloma (MM) induces expansion of bone marrow (BM) mesenchymal stem cells (MSCs), but others showed…”
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Proliferation and Molecular Risk Score of Low Risk Myeloma Cells Are Increased in High Risk Microenvironment Via Augmented Bioavailability of Growth Factors by Mehdi, Syed J., Johnson, Sarah K, Khan, Sharmin, Ling, Wen, Shelton, Randal, Epstein, Joshua, van Rhee, Frits, Zangari, Maurizio, Schinke, Carolina D., Thanendrarajan, Sharmilan, Walker, Brian A, Ashby, Cody, Davies, Faith E., Morgan, Gareth, Yaccoby, Shmuel

“…Introduction: Multiple myeloma (MM) cells from patients with smoldering MM (SMM) and low-risk (LR) MM harbor genetic alterations typically seen in patients…”
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Single-Cell Analysis of Mesenchymal Stem Cells Reveals Their Molecular and Functional Heterogeneity in Myeloma by Mehdi, Syed J., Johnson, Sarah K, Epstein, Joshua, Khan, Sharmin, Ling, Wen, Shelton, Randal, Zangari, Maurizio, Qu, Pingping, Hoering, Antje, van Rhee, Frits, Schinke, Carolina D., Thanendrarajan, Sharmilan, Wardell, Christopher P., Davies, Faith E., Morgan, Gareth J., Yaccoby, Shmuel

“…Introduction Bone marrow (BM) mesenchymal stem cells (MSCs) are rare but heterogeneous cell populations, and both MSCs and their lineages mediate BM niches,…”
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