Search Results - "Mehanna, Ahmed S"
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Design, synthesis, and biological testing of thiosalicylamides as a novel class of calcium channel blockers
Published in Bioorganic & medicinal chemistry (01-07-2005)“…[Display omitted] The current research aimed to investigate the importance of the heterocyclic ring system in the structure of the cardiovascular drug…”
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Synthesis of triphenylphosphonium phospholipid conjugates for the preparation of mitochondriotropic liposomes
Published in Methods in molecular biology (Clifton, N.J.) (2015)“…Surface modification of liposomes with a ligand is facilitated by the conjugation of the ligand to a hydrophobic molecule that serves to anchor the ligand to…”
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Hydrophobized triphenyl phosphonium derivatives for the preparation of mitochondriotropic liposomes: choice of hydrophobic anchor influences cytotoxicity but not mitochondriotropic effect
Published in Journal of liposome research (02-01-2016)“…Context: Nanocarrier-based strategies to achieve delivery of bioactives specifically to the mitochondria are being increasingly explored due to the importance…”
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Design, synthesis and biological evaluation of a series of thioamides as non-nucleoside reverse transcriptase inhibitors
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-11-2007)“…A series of thioamides were designed as bio-isosteres to the non-nucleoside reverse transcriptase inhibitor trovirdine by replacement of the thiourea NH groups…”
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Liquid chromatographic determination of hippuric acid for the evaluation of ethacrynic acid as angiotensin converting enzyme inhibitor
Published in Journal of pharmaceutical and biomedical analysis (01-05-1999)“…A rapid, simple and interference-free method is described to evaluate the inhibitory effects of organic compounds on the activity of angiotensin converting…”
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Comparison of crystal and solution hemoglobin binding of selected antigelling agents and allosteric modifiers
Published in Biochemistry (Easton) (24-04-1990)“…This paper details comprehensive binding studies (solution and X-ray) of human hemoglobin A with a group of halogenated carboxylic acids that were investigated…”
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Using Molecular Docking to Develop Inhibitors of DPP‐IV Enzyme
Published in The FASEB journal (01-04-2018)“…Dipeptidyl peptidase‐IV enzyme is a relatively new target for type 2 diabetes. Sitagliptin is the first FDA approved inhibitor of this enzyme to be introduced…”
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Allosteric modifiers of hemoglobin. 1. Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin oxygen affinity decreasing agents
Published in Journal of medicinal chemistry (01-02-1991)“…Three isomeric series of 2-(aryloxy)-2-methylpropionic acids were prepared and studied for their ability to decrease the oxygen affinity of human hemoglobin A…”
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Insulin and Oral Antidiabetic Agents
Published in American journal of pharmaceutical education (01-01-2005)“…The current manuscript describes an overview for therapeutic approaches to treat diabetes mellitus. Detailed presentation of the role of insulin in both…”
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NSAIDs: Chemistry and Pharmacological Actions
Published in American journal of pharmaceutical education (01-01-2003)Get full text
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Insulin and Oral Antidiabetic Agents
Published in American journal of pharmaceutical education (01-01-2005)Get full text
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NSAIDs: Chemistry and Pharmacological Actions
Published in American journal of pharmaceutical education (01-03-2003)Get full text
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NSAIDs: Chemistry and Pharmacological Actions
Published in American journal of pharmaceutical education (2003)Get full text
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Design, synthesis, and testing of potential antisickling agents. 1. Halogenated benzyloxy and phenoxy acids
Published in Journal of medicinal chemistry (01-09-1982)Get full text
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Vanillin, a Potential Agent for the Treatment of Sickle Cell Anemia
Published in Blood (15-03-1991)“…Vanillin, a food additive, has been evaluated as a potential agent to treat sickle cell anemia. Earlier studies indicated that vanillin had moderate…”
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Novel Therapeutic Targets for Antiarrhythmic Drugs. Edited by George E. Billman
Published in ChemMedChem (05-07-2010)“…Wiley, Hoboken 2010. 586 pp., hardcover $ 149.95.—ISBN 978‐0‐470‐26100‐2…”
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