Search Results - "Mehanna, Ahmed S"

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  1. 1

    Design, synthesis, and biological testing of thiosalicylamides as a novel class of calcium channel blockers by Mehanna, Ahmed S., Kim, Jin Yung

    Published in Bioorganic & medicinal chemistry (01-07-2005)
    “…[Display omitted] The current research aimed to investigate the importance of the heterocyclic ring system in the structure of the cardiovascular drug…”
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    Journal Article
  2. 2

    Synthesis of triphenylphosphonium phospholipid conjugates for the preparation of mitochondriotropic liposomes by Benien, Parul, Benein, Parul, Almuteri, Mohammed A, Mehanna, Ahmed S, D'Souza, Gerard G M

    “…Surface modification of liposomes with a ligand is facilitated by the conjugation of the ligand to a hydrophobic molecule that serves to anchor the ligand to…”
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  3. 3

    Hydrophobized triphenyl phosphonium derivatives for the preparation of mitochondriotropic liposomes: choice of hydrophobic anchor influences cytotoxicity but not mitochondriotropic effect by Benien, Parul, Solomon, Melani A., Nguyen, Paul, Sheehan, Erin M., Mehanna, Ahmed S., D'Souza, Gerard G. M.

    Published in Journal of liposome research (02-01-2016)
    “…Context: Nanocarrier-based strategies to achieve delivery of bioactives specifically to the mitochondria are being increasingly explored due to the importance…”
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  4. 4

    Design, synthesis and biological evaluation of a series of thioamides as non-nucleoside reverse transcriptase inhibitors by Mehanna, Ahmed S, Belani, Jitendra D, Kelley, Charles J, Pallansc, Luke A

    “…A series of thioamides were designed as bio-isosteres to the non-nucleoside reverse transcriptase inhibitor trovirdine by replacement of the thiourea NH groups…”
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  5. 5

    Liquid chromatographic determination of hippuric acid for the evaluation of ethacrynic acid as angiotensin converting enzyme inhibitor by Mehanna, Ahmed S, Dowling, Mark

    “…A rapid, simple and interference-free method is described to evaluate the inhibitory effects of organic compounds on the activity of angiotensin converting…”
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  6. 6

    Comparison of crystal and solution hemoglobin binding of selected antigelling agents and allosteric modifiers by Mehanna, Ahmed S, Abraham, Donald J

    Published in Biochemistry (Easton) (24-04-1990)
    “…This paper details comprehensive binding studies (solution and X-ray) of human hemoglobin A with a group of halogenated carboxylic acids that were investigated…”
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    Using Molecular Docking to Develop Inhibitors of DPP‐IV Enzyme by Hendawy, Moataz A, Mehanna, Ahmed S, Shah, Rachit M

    Published in The FASEB journal (01-04-2018)
    “…Dipeptidyl peptidase‐IV enzyme is a relatively new target for type 2 diabetes. Sitagliptin is the first FDA approved inhibitor of this enzyme to be introduced…”
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  9. 9

    Allosteric modifiers of hemoglobin. 1. Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin oxygen affinity decreasing agents by Randad, Ramnarayan S, Mahran, Mona A, Mehanna, Ahmed S, Abraham, Donald J

    Published in Journal of medicinal chemistry (01-02-1991)
    “…Three isomeric series of 2-(aryloxy)-2-methylpropionic acids were prepared and studied for their ability to decrease the oxygen affinity of human hemoglobin A…”
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  10. 10

    Insulin and Oral Antidiabetic Agents by Mehanna, Ahmed S

    “…The current manuscript describes an overview for therapeutic approaches to treat diabetes mellitus. Detailed presentation of the role of insulin in both…”
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    Vanillin, a Potential Agent for the Treatment of Sickle Cell Anemia by Abraham, Donald J., Mehanna, Ahmed S., Wireko, Fred C., Whitney, James, Thomas, Robin P., Orringer, Eugene P.

    Published in Blood (15-03-1991)
    “…Vanillin, a food additive, has been evaluated as a potential agent to treat sickle cell anemia. Earlier studies indicated that vanillin had moderate…”
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  18. 18

    Novel Therapeutic Targets for Antiarrhythmic Drugs. Edited by George E. Billman by Mehanna, AhmedS.

    Published in ChemMedChem (05-07-2010)
    “…Wiley, Hoboken 2010. 586 pp., hardcover $ 149.95.—ISBN 978‐0‐470‐26100‐2…”
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