Search Results - "Meghji, Sajeda"

Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis by Joosten, Leo A B, Leoni, Flavio, Meghji, Sajeda, Mascagni, Paolo

“…Inhibition of histone deacetylases (HDAC) has been shown to modulate gene expression and cytokine production after stimulation with several stimuli. In the…”
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Hypoxia is a major stimulator of osteoclast formation and bone resorption by Arnett, Timothy R., Gibbons, Daniel C., Utting, Jennifer C., Orriss, Isabel R., Hoebertz, Astrid, Rosendaal, Martin, Meghji, Sajeda

“…Hypoxia is known to act as a general stimulator of cells derived from marrow precursors. We investigated the effect of oxygen tension on the formation and…”
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In vitro effects of therapeutic ultrasound on cell proliferation, protein synthesis, and cytokine production by human fibroblasts, osteoblasts, and monocytes by Doan, N, Reher, P, Meghji, S, Harris, M

“…The aim of this study was to evaluate several in vitro effects of ultrasound that could revert or prevent the hypoxia, hypovascularity, and hypocellularity…”
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Binding Immunoglobulin Protein (BIP) Inhibits TNF‐α–Induced Osteoclast Differentiation and Systemic Bone Loss in an Erosive Arthritis Model by Zaiss, Mario M., Hall, Christopher, McGowan, Neil W. A., Babb, Rebecca, Devlia, Vikesh, Lucas, Sébastien, Meghji, Sajeda, Henderson, Brian, Bozec, Aline, Schett, Georg, David, Jean‐Pierre, Panayi, Gabriel S., Grigoriadis, Agamemnon E., Corrigall, Valerie M.

“…Objective The association between inflammation and dysregulated bone remodeling is apparent in rheumatoid arthritis and is recapitulated in the human tumor…”
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EFFECT OF ULTRASOUND ON THE PRODUCTION OF IL-8, BASIC FGF AND VEGF by Reher, Peter, Doan, Nghiem, Bradnock, Brian, Meghji, Sajeda, Harris, Malcolm

“…Therapeutic angiogenesis is the controlled induction or stimulation of new blood vessel formation to reduce unfavourable tissue effects caused by local hypoxia…”
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Long wave ultrasound may enhance bone regeneration by altering OPG/RANKL ratio in human osteoblast-like cells by Maddi, Abhiram, Hai, HoKee, Ong, Siew-Tin, Sharp, Lindsay, Harris, Malcolm, Meghji, Sajeda

“…Human osteoblast cell line (MG63) cells were treated with long wave (45 kHz, intensity 30 mW/cm 2) continuous ultrasound (US) for 5 min and incubated for…”
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Staphylococcus aureus Fibronectin Binding Proteins Are Essential for Internalization by Osteoblasts but Do Not Account for Differences in Intracellular Levels of Bacteria by AHMED, Saddif, MEGHJI, Sajeda, WILLIAMS, Rachel J, HENDERSON, Brian, BROCK, Jeremy H, NAIR, Sean P

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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pH dependence of bone resorption: mouse calvarial osteoclasts are activated by acidosis by Meghji, S, Morrison, M S, Henderson, B, Arnett, T R

“…We examined the effects of HCO(3)(-) and CO(2) acidosis on osteoclast-mediated Ca(2+) release from 3-day cultures of neonatal mouse calvaria. Ca(2+) release…”
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A Study of the Uptake of Toluidine Blue O by Porphyromonas gingivalis and the Mechanism of Lethal Photosensitization by Bhatti, Manpreet, MacRobert, Alexander, Meghji, Sajeda, Henderson, Brian, Wilson, Michael

“…ABSTRACT The purpose of the study was to determine the distribution of the photosensitizer toluidine blue O (TBO) within Porphyromonas gingivalis and the…”
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Effect of Dosimetric and Physiological Factors on the Lethal Photosensitization of Porphyromonas gingivalis in vitro by Bhatti, Manpreet, MacRobert, Alexander, Meghji, Sajeda, Henderson, Brian, Wilson, Michael

“…ABSTRACT The aims of this study were to (1) determine the effect of dosimetric and physiological factors on the lethal photosensitization of Porphyromonas…”
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The stimulation of bone formation in vitro by therapeutic ultrasound by Reher, P, Elbeshir el-NI, Harvey, W, Meghji, S, Harris, M

“…A controlled study was performed to evaluate the effects of different ultrasound (US) intensities on 5-day-old mouse calvaria bone in tissue culture. A special…”
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Mycobacterium tuberculosis chaperonin 10 stimulates bone resorption: a potential contributory factor in Pott's disease by Meghji, S, White, P A, Nair, S P, Reddi, K, Heron, K, Henderson, B, Zaliani, A, Fossati, G, Mascagni, P, Hunt, J F, Roberts, M M, Coates, A R

“…Pott's disease (spinal tuberculosis), a condition characterized by massive resorption of the spinal vertebrae, is one of the most striking pathologies…”
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The effect of ultrasound on angiogenesis: an in vivo study using the chick chorioallantoic membrane by Ramli, Rosalina, Reher, Peter, Harris, Malcolm, Meghji, Sajeda

“…Ultrasound therapy induces clinical healing of irradiated avascular mandibular bone and fractures. In vitro ultrasound in tissue culture has been shown to…”
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Clinical oral science: edited by Malcolm Harris, Michael Edgar, Sajeda Meghji by Harris, Malcolm, Edgar, W. M, Meghji, Sajeda

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Invasion of bone cells by Staphylococcus epidermidis by Khalil, Hesham, Williams, Rachel J., Stenbeck, Gudrun, Henderson, Brian, Meghji, Sajeda, Nair, Sean P.

“…Bone implants infected with Staphylococcus epidermidis often require surgical intervention because of the failure of antibiotic treatment. The reasons why such…”
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Dual elevation of cyclic AMP and inositol phosphates in response to mechanical deformation of murine osteoblasts by Sandy, J R, Meghji, S, Farndale, R W, Meikle, M C

“…Mechanical deformation of bone cells was thought to be mediated via prostaglandin production and the cyclic AMP pathway. We present evidence that the…”
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Stimulation of bone resorption by lipoxygenase metabolites of arachidonic acid by Meghji, S, Sandy, J R, Scutt, A M, Harvey, W, Harris, M

“…We have studied the effect of leukotrienes, (LT): B4, C4, D4 and E4 and the hydroxyeicosatetraenoic acids (HETEs) 5-HETE and 12-HETE on bone resorption in…”
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Extracellular ADP is a powerful osteolytic agent: evidence for signaling through the P2Y1 receptor on bone cells by HOEBERTZ, ASTRID, MEGHJI, SAJEDA, BURNSTOCK, GEOFFREY, ARNETT, TIMOTHY R.

“…ABSTRACT There is increasing evidence that extracellular nucleotides act on bone cells via P2 receptors. This study investigated the action of ADP and…”
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Bacterially induced bone destruction: mechanisms and misconceptions by NAIR, S. P, MEGHJI, S, WILSON, M, REDDI, K, WHITE, P, HENDERSON, B

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Mechanisms of internalization of Staphylococcus aureus by cultured human osteoblasts by Jevon, M, Guo, C, Ma, B, Mordan, N, Nair, S P, Harris, M, Henderson, B, Bentley, G, Meghji, S

“…Staphylococcus aureus is an important bone pathogen, and evidence shows that this organism is internalized by chick osteoblasts. Here we report that S. aureus…”
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