Search Results - "Meganathan Kannan"

Editorial: Innate immunity: platelets and their interaction with other cellular elements in host defense and disease pathogenesis by Kannan, Meganathan, Ahmad, Firdos, Shankar, Esaki M

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Differential profiling of human red blood cells during storage for 52 selected microRNAs by Kannan, Meganathan, Atreya, Chintamani

“…BACKGROUND: MicroRNAs (miRNAs), the negative regulators of cellular mRNAs, are present in mature red blood cells (RBCs) in abundance relative to other blood…”
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Characterization of VWF gene conversions causing von Willebrand disease by Ahmad, Firdos, Kannan, Meganathan, Obser, Tobias, Budde, Ulrich, Schneppenheim, Sonja, Saxena, Renu, Schneppenheim, Reinhard

“…Summary We previously reported that von Willebrand Factor gene (VWF) conversions are a relatively frequent cause of von Willebrand disease (VWD), however,…”
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SARS‐CoV‐2 infection induces soluble platelet activation markers and PAI‐1 in the early moderate stage of COVID‐19 by Al‐Tamimi, Abaher O., Yusuf, Ayesha M., Jayakumar, Manju N., Ansari, Abdul W., Elhassan, Mona, AbdulKarim, Fatema, Kannan, Meganathan, Halwani, Rabih, Ahmad, Firdos

“…Introduction Coagulation dysfunction and thromboembolism emerge as strong comorbidity factors in severe COVID‐19. However, it is unclear when particularly…”
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The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology by Gresele, Paolo, Falcinelli, Emanuela, Bury, Loredana, Pecci, Alessandro, Alessi, Marie‐Christine, Borhany, Munira, Heller, Paula G., Santoro, Cristina, Cid, Ana Rosa, Orsini, Sara, Fontana, Pierre, De Candia, Erica, Podda, Gianmarco, Kannan, Meganathan, Jurk, Kerstin, Castaman, Giancarlo, Falaise, Céline, Guglielmini, Giuseppe, Noris, Patrizia, Zaninetti, Carlo, Fiore, Mathieu, Tosetto, Alberto, Zuniga, Pamela, Miyazaki, Koji, Dupuis, Arnaud, Hayward, Catherine, Casonato, Alessandra, Grandone, Elvira, Mazzucconi, Maria Gabriella, James, Paula, Fabris, Fabrizio, Henskens, Yvonne, Napolitano, Mariasanta, Curnow, Jennifer, Gkalea, Vasiliki, Fedor, Marian, Lambert, Michele P., Zieger, Barbara, Barcella, Luca, Cosmi, Benilde, Giordano, Paola, Porri, Claudia, Melazzini, Federica, Abid, Madiha, Glembotsky, Ana C., Ferrara, Grazia, Russo, Alexandra, Deckmyn, Hans, Frelinger, Andrew L., Harrison, Paul, Mezzano, Diego, Mumford, Andrew D, Lordkipanidzé, Marie

“…Background The ISTH Bleeding Assessment Tool (ISTH‐BAT) has been validated for clinical screening of suspected von Willebrand disease (VWD) and for bleeding…”
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Genomic surveillance of omicron B.1.1.529 SARS‐CoV‐2 and its variants between December 2021 and March 2023 in Tamil Nadu, India—A state‐wide prospective longitudinal study by Selvavinayagam, Sivaprakasam T., Suvaithenamudhan, Suvaiyarasan, Yong, Yean K., Hemashree, Kannan, Rajeshkumar, Manivannan, Kumaresan, Anandhazhvar, Arthydevi, Parthiban, Kannan, Meganathan, Gopalan, Natarajan, Vignesh, Ramachandran, Murugesan, Amudhan, Sivasankaran, Munusamy P., Sankar, Sathish, Cheedarla, Narayanaiah, Anshad, Abdul R., Govindaraj, Sakthivel, Zhang, Ying, Tan, Hong Y., Larsson, Marie, Saravanan, Shanmugam, Balakrishnan, Pachamuthu, Kulanthaivel, Langeswaran, Singh, Kamalendra, Joseph, Narcisse, Velu, Vijayakumar, Byrareddy, Siddappa N., Shankar, Esaki M., Raju, Sivadoss

“…A state‐wide prospective longitudinal investigation of the genomic surveillance of the omicron B.1.1.529 SARS‐CoV‐2 variant and its sublineages in Tamil Nadu,…”
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Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations by Selvavinayagam, Sivaprakasam T., Sankar, Sathish, Yong, Yean K., Murugesan, Amudhan, Suvaithenamudhan, Suvaiyarasan, Hemashree, Kannan, Rajeshkumar, Manivannan, Kumaresan, Anandhazhvar, Pandey, Ramendra P., Shanmugam, Saravanan, Arthydevi, Parthiban, Kumar, Masilamani Senthil, Gopalan, Natarajan, Kannan, Meganathan, Cheedarla, Narayanaiah, Tan, Hong Y., Zhang, Ying, Larsson, Marie, Balakrishnan, Pachamuthu, Velu, Vijayakumar, Byrareddy, Siddappa N., Shankar, Esaki M., Raju, Sivadoss

“…In December 2023, we observed a notable shift in the COVID-19 landscape, when JN.1 omicron emerged as the predominant SARS-CoV-2 variant with a 95% incidence…”
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Study of Prothrombotic Gene Variations Associated with the Risk of Development of Thrombosis in Patients with Down Syndrome by Kataru, Chandreswara Raju, Krishnakumar, Vinodhini, Panigrahi, Inusha, Kannan, Meganathan

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Depolarized Mitochondrial Membrane Potential and Elevated Calcium in Platelets of Sickle Cell Disease by Maharana, Samarjit, Roy, Chitrali Laha, Kishor, Kamal, Ranjan, Ravi, Ahmad, Firdos, Mahapatra, Manoranjan, Saxena, Renu, Kannan, Meganathan

“…Hemolysis, a crucial feature of Sickle cell disease (SCD), is a key player for cellular activation leading to various complications including thrombosis. In…”
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Synergistic Effect of Surfactant on Disperser Energy and Liquefaction Potential of Macroalgae (Ulva intestinalis) for Biofuel Production by Puthiya Veettil, Rinsha, Rabia, Mathew, Dinesh Kumar, Gondi, Rashmi, Sankarapandian, Kavitha, Kannan, Meganathan, Kumar, Gopalakrishnan, Al-Qaradawi, Siham Y., Jeyakumar, Rajesh Banu

“…The objective of this study was to evaluate the effect of surfactant on disperser homogenization pretreatment for macroalgae (Ulva intestinalis) to enhance…”
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Low SARS-CoV-2 viral load among vaccinated individuals infected with Delta B.1.617.2 and Omicron BA.1.1.529 but not with Omicron BA.1.1 and BA.2 variants by Selvavinayagam, Sivaprakasam T, Yong, Yean Kong, Joseph, Narcisse, Hemashree, Kannan, Tan, Hong Yien, Zhang, Ying, Rajeshkumar, Manivannan, Kumaresan, Anandhazhvar, Kalpana, Raghu, Kalaivani, Vasudevan, Monika, Ayyagari Venkata Devi, Suvaithenamudhan, Suvaiyarasan, Kannan, Meganathan, Murugesan, Amudhan, Narayanasamy, Krishnasamy, Palani, Sampath, Larsson, Marie, Shankar, Esaki M, Raju, Sivadoss

“…The rapid spread of SARS-CoV-2 variants in the global population is indicative of the development of selective advantages in emerging virus strains. Here, we…”
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Glanzmann's thrombasthenia: an overview by Kannan, Meganathan, Saxena, Renu

“…Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited bleeding disorder due to a defect in platelet function. The hallmark of this disease is…”
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Viral Persistence and Chronicity in Hepatitis C Virus Infection: Role of T-Cell Apoptosis, Senescence and Exhaustion by Barathan, Muttiah, Mohamed, Rosmawati, Yong, Yean K, Kannan, Meganathan, Vadivelu, Jamuna, Saeidi, Alireza, Larsson, Marie, Shankar, Esaki Muthu

“…Hepatitis C virus (HCV) represents a challenging global health threat to ~200 million infected individuals. Clinical data suggest that only ~10⁻15% of acutely…”
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Attrition in serum anti-DENV antibodies correlates with high anti-SARS-CoV-2 IgG levels and low DENV positivity in mosquito vectors—Findings from a state-wide cluster-randomized community-based study in Tamil Nadu, India by Selvavinayagam, Sivaprakasam T., Sankar, Sathish, Yong, Yean K., Anshad, Abdul R., Chandramathi, Samudi, Somasundaram, Anavarathan, Palani, Sampath, Kumarasamy, Parthipan, Azhaguvel, Roshini, Kumar, Ajith B., Subramaniam, Sudharshini, Malathi, Manickam, Vijayalakshmi, Venkatachalam, Rajeshkumar, Manivannan, Kumaresan, Anandhazhvar, Pandey, Ramendra P., Muruganandam, Nagarajan, Gopalan, Natarajan, Kannan, Meganathan, Murugesan, Amudhan, Balakrishnan, Pachamuthu, Byrareddy, Siddappa N., Dash, Aditya P., Velu, Vijayakumar, Larsson, Marie, Shankar, Esaki M., Raju, Sivadoss

“…The decline in dengue incidence and/or prevalence during the COVID-19 pandemic (2020–22) appears to be attributed to reduced treatment-seeking rates,…”
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Plasma CXCL8 and MCP-1 as surrogate plasma biomarkers of latent tuberculosis infection among household contacts-A cross-sectional study by Selvavinayagam, Sivaprakasam T, Aswathy, Bijulal, Yong, Yean K, Frederick, Asha, Murali, Lakshmi, Kalaivani, Vasudevan, Karishma, Sree J, Rajeshkumar, Manivannan, Anusree, Adukkadukkam, Kannan, Meganathan, Gopalan, Natarajan, Vignesh, Ramachandran, Murugesan, Amudhan, Tan, Hong Yien, Zhang, Ying, Chandramathi, Samudi, Sivasankaran, Munusamy Ponnan, Balakrishnan, Pachamuthu, Govindaraj, Sakthivel, Byrareddy, Siddappa N, Velu, Vijayakumar, Larsson, Marie, Shankar, Esaki M, Raju, Sivadoss

“…Early detection of latent tuberculosis infection (LTBI) is critical to TB elimination in the current WHO vision of End Tuberculosis Strategy. The study…”
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Coinheritance of severe von Willebrand disease with Glanzmann thrombasthenia by Ahmad, Firdos, Kannan, Meganathan, Kishor, Kamal, Saxena, Renu

“…A 35-years old male patient presented severe bleeding was diagnosed to have type 3 von Willebrand disease (VWD) and carrier for Glanzmann thrombasthenia (GT)…”
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Platelet activation markers in evaluation of thrombotic risk factors in various clinical settings by Kannan, Meganathan, Ahmad, Firdos, Saxena, Renu

“…Platelets play a major role in primary hemostasis and thrombus formation. After vascular injury, platelets adhere to injured site and rapidly change their…”
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Disseminated intravascular coagulation in acute leukemia at presentation and during induction therapy by Dixit, Ashish, Chatterjee, Tathagat, Mishra, Pravas, Kannan, Meganathan, Choudhry, Dharma R, Mahapatra, Manoranjan, Choudhry, V P, Saxena, Renu

“…Between January 2001 and December 2003, 67 patients with acute leukemia were evaluated prospectively for hemostatic abnormality at presentation, of which 43…”
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Impact of thrombogenic mutations on clinical phenotypes of von Willebrand disease by Ahmad, Firdos, Kannan, Meganathan, Yadav, Vinita, Biswas, Arijit, Saxena, Renu

“…von Willebrand disease (VWD) is a most common inherited bleeding disorder. von Willebrand factor (VWF) exists as an extracellular adaptor molecule and…”
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Hypercoagulable state in five thalassemia intermedia patients by Bhattacharyya, Maitreyee, Kannan, Meganathan, Chaudhry, Ved P, Mahapatra, M, Pati, H, Saxena, Renu

“…Fifty-three patients of thalassemia intermedia and 40 controls were studied for clinical evidence of thrombosis and laboratory evidence of hypercoagulable…”
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