Search Results - "Mega, William"

Integrative Omic Analysis of Experimental Bacteremia Identifies a Metabolic Signature That Distinguishes Human Sepsis from Systemic Inflammatory Response Syndromes by LANGLEY, Raymond J, TIPPER, Jennifer L, KEATON, Mignon, KENSICKI, Elizabeth, GAZOURIAN, Lee, FREDENBURGH, Laura E, MASSARO, Anthony F, OTERO, Ronny M, FOWLER, Vance G, RIVERS, Emanuel P, WOODS, Chris W, KINGSMORE, Stephen F, BRUSE, Shannon, SOPORI, Mohan L, PERRELLA, Mark A, CHOI, Augustine M. K, HARROD, Kevin S, BARON, Rebecca M, TSALIK, Ephraim L, HUNTLEY, James, ROGERS, Angela J, JARAMILLO, Richard J, O'DONNELL, Denise, MEGA, William M

“…Sepsis is a leading cause of morbidity and mortality. Currently, early diagnosis and the progression of the disease are difficult to make. The integration of…”
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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection by Reed, Matthew D, Wilder, Julie A, Mega, William M, Hutt, Julie A, Kuehl, Philip J, Valderas, Michelle W, Chew, Lawrence L, Liang, Bertrand C, Squires, Charles H

“…Protective antigen (PA), one of the components of the anthrax toxin, is the major component of human anthrax vaccine (Biothrax). Human anthrax vaccines…”
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Plazomicin is effective in a non-human primate pneumonic plague model by Mega, William M., Doyle-Eisele, Melanie, Cass, Robert T., Kostrub, Corwin F., Sherwood, Robert L., Metz, Matthew A., Cirz, Ryan T.

“…[Display omitted] The efficacy of plazomicin for pneumonic plague was evaluated in a non-human primate model. African Green monkeys challenged with a lethal…”
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Levofloxacin cures experimental pneumonic plague in African green monkeys by Layton, Robert Colby, Mega, William, McDonald, Jacob D, Brasel, Trevor L, Barr, Edward B, Gigliotti, Andrew P, Koster, Frederick

“…Yersinia pestis, the agent of plague, is considered a potential bioweapon due to rapid lethality when delivered as an aerosol. Levofloxacin was tested for…”
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A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus by Roy, Chad J, Adams, A. Paige, Wang, Eryu, Leal, Grace, Seymour, Robert L, Sivasubramani, Satheesh K, Mega, William, Frolov, Ilya, Didier, Peter J, Weaver, Scott C

“…Highlights ► Chimeric vaccines were constructed from a cDNA clone containing genes from divergent EEE strains. ► The immunogenicity of each of the vaccines…”
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Telemetry used to determine efficacy of intravenous plazomicin against inhaled tularemia in cynomolgus macaques (CM) by Bruse, Kristy, Mega, William, Overheim, Katie, Cirz, R., Cass, R., Valderas, Michelle, Sherwood, Robert

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Protection in mice passively immunized with serum from cynomolgus macaques and humans vaccinated with recombinant plague vaccine (rF1V) by Fellows, Patricia, Adamovicz, Jeffrey, Hartings, Justin, Sherwood, Robert, Mega, William, Brasel, Trevor, Barr, Ed, Holland, Lou, Lin, Winston, Rom, Amanda, Blackwelder, William, Price, Jessica, Morris, Stephen, Snow, Doris, Hart, Mary Kate

“…Abstract Passive transfer models were developed to evaluate the ability of antibodies generated in cynomolgus macaques and humans vaccinated with a recombinant…”
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Telemetry use in infectious disease/biodefense: Biomarkers for model development and efficacy evaluation by Layton, Robert C., Mega, William, Koster, Frederick T.

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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection: e0130952 by Reed, Matthew D, Wilder, Julie A, Mega, William M, Hutt, Julie A, Kuehl, Philip J, Valderas, Michelle W, Chew, Lawrence L, Liang, Bertrand C, Squires, Charles H

“…Protective antigen (PA), one of the components of the anthrax toxin, is the major component of human anthrax vaccine (Biothrax). Human anthrax vaccines…”
Get full text