Identified small RNAs of Mycobacterium avium

Posttranscriptional regulation of gene expression by small RNAs was shown for multiple pathogenic microorganisms and plays an important role in virulence. 4 putative sRNA genes located in intergenic loci were identified: MAV_0380-0381 (4.5S RNA), MAV_1034-1035 (trans-encoded sRNA), MAV_1415-1416 (an...

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Bibliographic Details
Published in:	Bioorganicheskaia khimiia Vol. 38; no. 4; p. 509
Main Authors:	Ignatov, D V, Mefod'eva, L G, Maĭorov, K B, Skvortsov, T A, Azhikina, T L
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-2012
Subjects:	Gene Expression Regulation, Bacterial Genomics Molecular Sequence Data Mycobacterium avium - chemistry Mycobacterium avium - pathogenicity RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics RNA, Small Untranslated - genetics RNA, Small Untranslated - isolation & purification
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Summary:	Posttranscriptional regulation of gene expression by small RNAs was shown for multiple pathogenic microorganisms and plays an important role in virulence. 4 putative sRNA genes located in intergenic loci were identified: MAV_0380-0381 (4.5S RNA), MAV_1034-1035 (trans-encoded sRNA), MAV_1415-1416 (antisense or trans-encoded sRNA) and MAV_1531-1532 (processed 5' UTR of 16S rRNA gene). The revealed sRNAs represent the first small noncoding RNAs identified in M. avium.
ISSN:	0132-3423