Search Results - "Meeusen, E."

Immunity to Haemonchus contortus and Vaccine Development by Nisbet, A J, Meeusen, E N, González, J F, Piedrafita, D M

“…Sheep are capable of developing protective immunity to Haemonchus contortus through repeated exposure to this parasite, although this immune protection is the…”
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The adjuvant system AS01 up‐regulates neutrophil CD14 expression and neutrophil‐associated antigen transport in the local lymphatic network by Neeland, M. R., Shi, W., Collignon, C., Meeusen, E. N. T., Didierlaurent, A. M., de Veer, M. J.

“…Summary The liposome‐based adjuvant system AS01 is under evaluation for use in several vaccines in clinical development. We have shown previously that AS01…”
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Galectin-11: A novel host mediator targeting specific stages of the gastrointestinal nematode parasite, Haemonchus contortus by Preston, S.J.M., Beddoe, T., Walkden-Brown, S., Meeusen, E., Piedrafita, D.

“…[Display omitted] •Galectin-11 binds to L4 and adult parasites but not L3.•Recombinant galectin-11 inhibits larval growth and development.•To our knowledge,…”
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Novel immunomic technologies for schistosome vaccine development by McWILLIAM, H. E. G., DRIGUEZ, P., PIEDRAFITA, D., McMANUS, D. P., MEEUSEN, E. N. T.

“…Summary Schistosomiasis remains one of the most common human helminthiases, despite the availability of an effective drug against the causative parasites. Drug…”
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Resistance to liver fluke infection in the natural sheep host is correlated with a type‐1 cytokine response by PLEASANCE, J., WIEDOSARI, E., RAADSMA, H. W., MEEUSEN, E., PIEDRAFITA, D.

“…Summary Indonesian thin‐tail (ITT) sheep can resist infection with Fasciola gigantica but not F. hepatica and presents an ideal model to investigate the…”
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Field vaccination of sheep with a larval-specific antigen of the gastrointestinal nematode, Haemonchus contortus , confers significant protection against an experimental challenge infection by Piedrafita, D.P, de Veer, M.J, Sherrard, J, Kraska, T, Elhay, M, Meeusen, E.N

“…Highlights ► Sheep were vaccinated on pasture with a larval-specific antigen. ► Only two immunizations using an approved adjuvant were administered. ►…”
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Eosinophil interactions with Haemonchus contortus larvae in the ovine gastrointestinal tract by Balic, A, Cunningham, C.P, Meeusen, E.N.T

“…Sheep were immunized by weekly oral infections with Haemonchus contortus for 9 weeks followed by anthelmintic treatment. They were challenged either 9 or 22…”
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Induction of allergic inflammation in the lungs of sensitized sheep after local challenge with house dust mite by Bischof, R. J., Snibson, K., Shaw, R., Meeusen, E. N. T

“…Summary Background Previous sheep models of asthma are based on sheep sensitized to nematode (Ascaris) allergens and these have been used to evaluate the…”
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Immune mechanisms of resistance to gastrointestinal nematode infections in sheep by HEIN, W.R, PERNTHANER, A, PIEDRAFITA, D, MEEUSEN, E.N

“…Infections with gastrointestinal nematode parasites are a major problem for the sheep industry in Australia and New Zealand and have been the subject of…”
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Progress and new technologies for developing vaccines against gastrointestinal nematode parasites of sheep by Newton, S. E., Meeusen, E. N. T.

“…SUMMARY Despite the identification of highly effective native antigens for vaccination against Haemonchus contortus, particularly ‘hidden’ antigens derived…”
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Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite by Snibson, K. J., Bischof, R. J., Slocombe, R. F., Meeusen, E. N.

“…Summary Background Remodelling of airway walls is a significant morbidity factor in patients suffering from chronic asthma. The relationship between airway…”
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innate host defence against nematode parasites by DE VEER, M.J, KEMP, J.M, MEEUSEN, E.N.T

“…Nematode parasites cause significant infections in both humans and animals. They are complex, multicellular organisms that present unique challenges for the…”
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Galectin‐11 induction in the gastrointestinal tract of cattle following nematode and protozoan infections by HOORENS, P., RINALDI, M., MIHI, B., DREESEN, L., GRIT, G., MEEUSEN, E., LI, R. W., GELDHOF, P.

“…Summary Galectin‐11 (LGALS11) has been suggested to play an important role in protective immunity against gastrointestinal nematodes in ruminants. However, in…”
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Eosinophil-mediated killing of Haemonchus contortus larvae: effect of eosinophil activation and role of antibody, complement and interleukin-5 by Rainbird, M A, Macmillan, D, Meeusen, E N

“…Eosinophils have previously been shown to accumulate around the tissue invasive (L3) stage of sheep gastrointestinal parasites in vivo. In this study,…”
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Parasites and the immune system: a perspective from down under by ENGWERDA, C.R, MEEUSEN, E.N

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Mechanisms of immunity to Haemonchus contortus infection in sheep by Balic, A., Bowles, V. M., Meeusen, E. N. T.

“…Summary In two separate experiments, sheep were immunized by nine to 12 weekly immunizing infections with 4000 Haemonchus contortus third stage larva (L3),…”
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Local immune responses in sensitized sheep following challenge infection with Teladorsagia circumcincta by Balic, A., Bowles, V. M., Liu, Y. S., Meeusen, E. N. T.

“…ABSTRACT Sheep were sensitized by weekly infections with Teladorsagia circumcincta over a 9‐week period. After a 12‐week rest, sheep were divided into four…”
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Neighborhood Characteristics Related to Changes in Anthropometrics During a Lifestyle Intervention for Persons with Obesity by Brouwer, Boëlle J, Kuckuck, Susanne, Meeusen, Renate E H, Mohseni, Mostafa, Lengton, Robin, van Lenthe, Frank J, van Rossum, Elisabeth F C

“…Since obesity has emerged as a major public health concern, there is an urgent need to better understand factors related to weight gain and treatment success…”
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Clinical phenotypes of adults with monogenic and syndromic genetic obesity by Welling, Mila S., Mohseni, Mostafa, Meeusen, Renate E. H., Groot, Cornelis J., Boon, Mariëtte R., Kleinendorst, Lotte, Visser, Jenny A., Haelst, Mieke M., Akker, Erica L. T., Rossum, Elisabeth F. C.

“…Objective Considering limited evidence on diagnostics of genetic obesity in adults, we evaluated phenotypes of adults with genetic obesity. Additionally, we…”
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Cellular profiles in the abomasal mucosa and lymph node during primary infection with Haemonchus contortus in sheep by Balic, A, Bowles, V.M, Meeusen, E.N.T

“…Cellular changes in the abomasal tissue and draining abomasal lymph nodes were examined after primary infection of lambs with Haemonchus contortus for 3, 5 or…”
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