Search Results - "Meetei, Potshangbam Angamba"

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    Discovery of sulfone-resistant dihydropteroate synthase (DHPS) as a target enzyme for kaempferol, a natural flavanoid by Potshangbam, Angamba Meetei, Rathore, Ravindranath Singh, Nongdam, Potshangbam

    Published in Heliyon (01-02-2020)
    “…Kaempferol is a ubiquitous flavonoid, found in various plants having a wide range of known pharmacological activities, including antioxidant, antiinflammatory,…”
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    Journal Article
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    3D-QSAR and molecular docking studies of 2-pyrimidinecarbonitrile derivatives as inhibitors against falcipain-3 by Potshangbam, Angamba Meetei, Tanneeru, Karunakar, Reddy, Bandi Madhusudhan, Guruprasad, Lalitha

    Published in Bioorganic & medicinal chemistry letters (01-12-2011)
    “…3D-QSAR study with CoMFA and CoMSIA methods was carried out on a series of 2-pyrimidinecarbonitrile derivatives that exhibit activity against falcipain-3. The…”
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    Hyperoxidation of Peroxiredoxin 6 Induces Alteration from Dimeric to Oligomeric State by Shahnaj, Sharifun, Chowhan, Rimpy Kaur, Meetei, Potshangbam Angamba, Kakchingtabam, Pushpa, Herojit Singh, Khundrakpam, Rajendrakumar Singh, Laishram, Nongdam, Potshangbam, Fisher, Aron B, Rahaman, Hamidur

    Published in Antioxidants (02-02-2019)
    “…Peroxiredoxins(Prdx), the family of non-selenium glutathione peroxidases, are important antioxidant enzymes that defend our system from the toxic reactive…”
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    Ligand-Based Pharmacophore Modeling and Virtual Screening of RAD9 Inhibitors by Prasad, Nirmal K., Kanakaveti, Vishnupriya, Eadlapalli, Siddhartha, Vadde, Ramakrishna, Meetei, Angamba Potshangbam, Vindal, Vaibhav

    Published in Journal of chemistry (01-01-2013)
    “…Human RAD9 is a key cell-cycle checkpoint protein that participates in DNA repair, activation of multiple cell cycle phase checkpoints, and apoptosis. Aberrant…”
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    Studies on conformational changes induced by binding of pendimethalin with human serum albumin by Ahmad, Md. Irshad, Potshangbam, Angamba Meetei, Javed, Mehjbeen, Ahmad, Masood

    Published in Chemosphere (Oxford) (01-03-2020)
    “…Pendimethalin (PND) is a widely used herbicide in modern means of agricultural practices. So, its toxic residues exist extensively in the environment and can…”
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    CXCR4 as possible druggable target linking inflammatory bowel disease and Parkinson's disease by Dogra, Nitu, Jakhmola-Mani, Ruchi, Potshangbam, Angamba Meetei, Buch, Shilpa, Pande Katare, Deepshikha

    Published in Metabolic brain disease (01-03-2023)
    “…Parkinson’s disease (PD) is a chronic, progressive, and second most prevalent neurological disorder affecting the motor system. It has been found that people…”
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    MedPServer: A database for identification of therapeutic targets and novel leads pertaining to natural products by Potshangbam, Angamba Meetei, Polavarapu, Raja, Rathore, Ravindranath Singh, Naresh, Damuka, Prabhu, Nagu Prakash, Potshangbam, Nongdam, Kumar, Pravind, Vindal, Vaibhav

    Published in Chemical biology & drug design (01-04-2019)
    “…Natural products have been the source of treatment for various human diseases from time immemorial. Interests in natural product‐based scaffolds for the…”
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    Journal Article
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    Discovery of dual cation-π inhibitors of acetylcholinesterase: design, synthesis and biological evaluation by Damuka, Naresh, Kammari, Kurumurthy, Potshangbam, Angamba Meetei, Rathore, Ravindranath Singh, Kondapi, Anand K, Vindal, Vaibhav

    Published in Pharmacological reports (01-06-2020)
    “…Alzheimer's disease (AD) is a widespread dementia-related disease affecting mankind worldwide. A cholinergic hypothesis is considered the most effective target…”
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    The anti-oxidant enzyme, Prdx6 might have cis-acting regulatory sequence(s) by Shahnaj, Sharifun, Potshangbam, Angamba Meetei, Chowhan, Rimpy Kaur, Parray, Zahoor Ahmad, Kakchingtabam, Pushpa, Kumari, Anju, Islam, Asimul, Khan, Aslam, Singh, Laishram Rajendrakumar, Rahaman, Hamidur

    “…Peroxiredoxin 6 (Prdx6) is a ubiquitously expressed 1-cysteine Peroxiredoxin found throughout all phyla. In mammals, under different physiological conditions,…”
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    Med PS erver: A database for identification of therapeutic targets and novel leads pertaining to natural products by Potshangbam, Angamba Meetei, Polavarapu, Raja, Rathore, Ravindranath Singh, Naresh, Damuka, Prabhu, Nagu Prakash, Potshangbam, Nongdam, Kumar, Pravind, Vindal, Vaibhav

    Published in Chemical biology & drug design (01-04-2019)
    “…Natural products have been the source of treatment for various human diseases from time immemorial. Interests in natural product‐based scaffolds for the…”
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    Journal Article
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    Epoxydicoumarin Derivative is a Novel Non‐Nucleoside TLR8 Agonist: Screening, Synthesis and Biological Evaluation by Damuka, Naresh, Kammari, Kurumurthy, Potshangbam, Angamba Meetei, Kondapi, Anand Kumar, Vindal, Vaibhav

    Published in ChemistrySelect (Weinheim) (28-06-2021)
    “…Toll‐like receptors (TLRs) activate host innate immunity by recognizing microbial ligands and viral nucleic acids. Of late, TLR8 has emerged as an attractive…”
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    3D-QSAR and Molecular Docking Studies on Substituted Isothiazole Analogs as Inhibitors Against MEK-1 Kinase by Reddy, Bandi Madhusudhan, Tanneeru, Karunakar, Meetei, Potshangbam Angamba, Guruprasad, Lalitha

    Published in Chemical biology & drug design (01-01-2012)
    “…MEK‐1 and MEK‐2 are dual‐specificity kinases and important components in the mitogen‐activated protein kinase pathway. These enzymes are crucial for normal…”
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    ClosIndb: A resource for computationally derived information from clostridial genomes by Polavarapu, Raja, Meetei, Potshangbam Angamba, Midha, Mohit, Bharne, Dhammapal, Vindal, Vaibhav

    Published in Infection, genetics and evolution (01-07-2015)
    “…•ClosIndb is a web resource which host in silico analysis of clostridium species.•It adressed features like regulatory regions, orthologs, physicochemical…”
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    Modeling of babesipain-1 and identification of natural and synthetic leads for bovine babesiosis drug development by Meetei, Potshangbam Angamba, Rathore, R. S., Prabhu, N. Prakash, Vindal, Vaibhav

    Published in Journal of molecular modeling (01-04-2016)
    “…Babesiosis is a tick-borne, zoonotic disease caused by species of the intraerythrocytic protozoan Babesia . It is distributed all around the world and affects…”
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    In silico screening for identification of novel β-1,3-glucan synthase inhibitors using pharmacophore and 3D-QSAR methodologies by Meetei, Potshangbam Angamba, Rathore, R. .S., Prabhu, N. Prakash, Vindal, Vaibhav

    Published in SpringerPlus (04-07-2016)
    “…The enzyme β-1,3-glucan synthase, which catalyzes the synthesis of β-1,3-glucan, an essential and unique structural component of the fungal cell wall, has been…”
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    In silico screening for identification of novel [beta]-1,3-glucan synthase inhibitors using pharmacophore and 3D-QSAR methodologies by Meetei, Potshangbam Angamba, Rathore, R S, Prabhu, N Prakash, Vindal, Vaibhav

    Published in SpringerPlus (01-07-2016)
    “…The enzyme [beta]-1,3-glucan synthase, which catalyzes the synthesis of [beta]-1,3-glucan, an essential and unique structural component of the fungal cell…”
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    Journal Article