Search Results - "Meerten, Esther"
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Methotrexate plus or minus cetuximab as first‐line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib‐randomized phase II study Commence
Published in Head & neck (01-05-2020)“…Background Methotrexate in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) has limited progression‐free survival (PFS)…”
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Survival of patients with head and neck cancer with metachronous multiple primary tumors is surprisingly favorable
Published in Head & neck (01-06-2019)“…Background The objectives of this study are to determine the incidence and survival rate of patients with head and neck squamous cell carcinoma (HNSCC) with…”
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Phase I Study of Cisplatin, Hyperthermia, and Lapatinib in Patients With Recurrent Carcinoma of the Uterine Cervix in a Previously Irradiated Area
Published in The oncologist (Dayton, Ohio) (01-03-2015)“…Background. Patients with recurrent cervical cancer in a previously irradiated area might benefit from cisplatin combined with hyperthermia. Lapatinib inhibits…”
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Intraoperative Radiation Therapy Reduces Local Recurrence Rates in Patients With Microscopically Involved Circumferential Resection Margins After Resection of Locally Advanced Rectal Cancer
Published in International journal of radiation oncology, biology, physics (01-04-2014)“…Purpose Intraoperative radiation therapy (IORT) is advocated by some for patients with locally advanced rectal cancer (LARC) who have involved or narrow…”
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Safety and Feasibility of Additional Tumor Debulking to First‐Line Palliative Combination Chemotherapy for Patients with Multiorgan Metastatic Colorectal Cancer
Published in The oncologist (Dayton, Ohio) (01-08-2020)“…Introduction Local treatment of metastases is frequently performed in patients with multiorgan metastatic colorectal carcinoma (mCRC) analogous to selected…”
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Quality of Life During Neoadjuvant Treatment and After Surgery for Resectable Esophageal Carcinoma
Published in International journal of radiation oncology, biology, physics (01-05-2008)“…Purpose Because of the trade-off between the potentially negative quality-of-life (QoL) effects and uncertain favorable survival effect of neoadjuvant…”
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Comparison of toxicity and effectiveness between fixed-dose and body surface area-based dose capecitabine
Published in Therapeutic advances in medical oncology (01-04-2019)“…Background: Capecitabine is generally dosed based on body surface area (BSA). This dosing strategy has several limitations; however, evidence for alternative…”
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Fewer head and neck cancer diagnoses and faster treatment initiation during COVID-19 in 2020: A nationwide population-based analysis
Published in Radiotherapy and oncology (01-02-2022)“…•The head and neck cancer incidence was nearly 25% less during the first COVID wave.•The lower incidence was mainly observed in oral cavity and laryngeal…”
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HYpofractionated, dose-redistributed RAdiotherapy with protons and photons to combat radiation-induced immunosuppression in head and neck squamous cell carcinoma: study protocol of the phase I HYDRA trial
Published in BMC cancer (13-06-2023)“…Radiotherapy (RT) is the standard of care for most advanced head and neck squamous cell carcinoma (HNSCC) and results in an unfavorable 5-year overall survival…”
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Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial
Published in BMJ open (08-12-2019)“…IntroductionCytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) has become standard of care for patients with peritoneal metastases…”
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Systemic treatment for oesophageal cancer
Published in European journal of cancer (1990) (01-03-2005)“…Oesophageal cancer, in particular adenocarcinomas, has shown a rapid and largely unexplained increase in incidence in the Western world. Despite advances in…”
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Genetic Variants as Predictive Markers for Ototoxicity and Nephrotoxicity in Patients with Locally Advanced Head and Neck Cancer Treated with Cisplatin-Containing Chemoradiotherapy (The PRONE Study)
Published in Cancers (17-04-2019)“…Ototoxicity and nephrotoxicity are potentially irreversible side effects of chemoradiotherapy with cisplatin in locally advanced head and neck cancer (LAHNC)…”
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Genome-Wide Analyses of Nephrotoxicity in Platinum-Treated Cancer Patients Identify Association with Genetic Variant in RBMS3 and Acute Kidney Injury
Published in Journal of personalized medicine (28-05-2022)“…Nephrotoxicity is a common and dose-limiting side effect of platinum compounds, which often manifests as acute kidney injury or hypomagnesemia. This study…”
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Chemoradiation for advanced hypopharyngeal carcinoma: a retrospective study on efficacy, morbidity and quality of life
Published in European archives of oto-rhino-laryngology (01-03-2012)“…Chemoradiation (CRT) is a valuable treatment option for advanced hypopharyngeal squamous cell cancer (HSCC). However, long-term toxicity and quality of life…”
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Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: A prospective cross-over drug–drug interaction study
Published in European journal of cancer (1990) (01-04-2011)“…Abstract Background Omeprazole is one of the most prescribed medications worldwide and within the class of proton pump inhibitors, it is most frequently…”
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Long-term Oncological and Functional Outcomes of Chemoradiotherapy Followed by Organ-Sparing Transanal Endoscopic Microsurgery for Distal Rectal Cancer: The CARTS Study
Published in JAMA surgery (01-01-2019)“…Treatment of rectal cancer is shifting toward organ preservation aiming to reduce surgery-related morbidity. Short-term outcomes of organ-preserving strategies…”
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Prognostic factors for severe diarrhea in patients with locally advanced rectal carcinoma treated with neoadjuvant chemoradiation with capecitabine: A single-center cohort study
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e15176 Background: Chemoradiation with concomitant capecitabine (CRT) followed by total mesorectal excision is the standard of care for locally…”
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A comprehensive approach to defining the cutoff value of oligometastasis in head and neck squamous cell carcinoma
Published in Cancer (05-11-2024)“…Abstract Background Patients with limited distant metastatic disease, also known as oligometastasis, show better survival rates than polymetastatic patients,…”
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Accounting for fractionation and heterogeneous dose distributions in the modelling of osteoradionecrosis in oropharyngeal carcinoma treatment
Published in Radiotherapy and oncology (01-11-2023)“…•Interest in hypofractionated radiotherapy with more heterogeneous dose distributions is increasing.•Existing osteoradionecrosis (ORN) risk models cannot be…”
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