Search Results - "Meerpohl, H.G."

Cardiac safety of trastuzumab in combination with epirubicin and cyclophosphamide in women with metastatic breast cancer: results of a phase I trial by Untch, M, Eidtmann, H, du Bois, A, Meerpohl, H.G, Thomssen, Ch, Ebert, A, Harbeck, N, Jackisch, C, Heilman, V, Emons, G, Wallwiener, D, Wiese, W, Blohmer, J.-U, Höffken, K, Kuhn, W, Reichardt, P, Muscholl, M, Pauschinger, M, Langer, B, Lück, H.J

“…This prospective, parallel-group, dose-escalation study evaluated the cardiac safety of trastuzumab (Herceptin®) plus epirubicin/cyclophosphamide (EC) in women…”
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Cardiac safety of trastuzumab in combination with epirubicin and cyclophosphamide in women with metastatic breast cancer by Untch, M, Eidtmann, H, du Bois, A, Meerpohl, H.G, Thomssen, Ch, Ebert, A, Harbeck, N, Jackisch, C, Heilman, V, Emons, G, Wallwiener, D, Wiese, W, Blohmer, J.-U, Höffken, K, Kuhn, W, Reichardt, P, Muscholl, M, Pauschinger, M, Langer, B, Lück, H.J

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Extended phase II study of paclitaxel as a 3-h infusion in patients with ovarian cancer previously treated with platinum by du Bois, A., Lück, H.J., Buser, K., Meerpohl, H.G., Sessa, C., Klaassen, U., Meden, H., Bochtler, H., Diergarten, K.

“…An extended phase II study was performed to evaluate single-agent paclitaxel as salvage chemotherapy for ovarian cancer. The aim of this study was to evaluate…”
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Randomized Study Comparing Carboplatin/Cyclophosphamide and Cisplatin/Cyclophosphamide as First-Line Treatment in Patients with Stage III/IV Epithelial Ovarian Cancer and Small Volume Disease by Meerpohl, H.G., Sauerbrei, W., Kühnle, H., Schumacher, M., Pfleiderer, A.

“…Several randomized studies in patients with advanced ovarian cancer have dealt with the comparison of cisplatin and carboplatin when given as either a single…”
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Course, patterns, and risk-factors for chemotherapy-induced emesis in cisplatin-pretreated patients: a study with ondansetron by du Bois, A, Meerpohl, H G, Vach, W, Kommoss, F G, Fenzl, E, Pfleiderer, A

“…Vomiting and nausea are the most distressing side-effects of cancer chemotherapy. With standard antiemetic regimens (e.g. metoclopramide based combinations)…”
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Prospective investigation of the significance of cardiac markers, NT-pro Brain Natriuretic Peptide (NT-proBNP) and Troponin T (TnT), in the Hercules study of epirubicin/cyclophosphamide with or without trastuzumab (Herceptin®) by Langer, B, Muscholl, M, Pauschinger, M, Thomssen, C, Eidtmann, H, Untch, M, Meerpohl, H.G, du Bois, A, Weber, H, Lueck, H.J

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Clinical phase I study with one-hour paclitaxel infusion by Mross, K., Hauns, B., H˚ring, B., Bauknecht, T., Meerpohl, H. G., Unger, C., Maier-Lenz, H.

“…Background Paclitaxel (PAC) is one of the major anti-cancer drugs, effective in different tumors. Studies with 24-hour infusion with 135 mg/m2 and a three-hour…”
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Clinical and pharmacokinetic phase I study with taxol® given as short 1-hour intravenous infusion by Mross, K., Häring, B., Hauns, B., Maier-Lenz, H., Bauknecht, T., Meerpohl, H.G., Diergarten, K., Unger, C.

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Positron emission tomography helps to diagnose tumor emboli and residual disease in choriocarcinoma by HEBART, H, ERLEY, C, KASKAS, B, MAYER, R, KÖNIG, M, EINSELE, H, BOKEMEYER, C, MEERPOHL, H. G, FEINE, U, KANZ, L

“…Positron emission tomography (PET) has been shown capable of identifying malignant tissues. WB-PET imaging in two women with metastatic choriocarcinoma is…”
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Pathophysiology, severity, pattern, and risk factors for carboplatin-induced emesis by du Bois, A, Vach, W, Kiechle, M, Cramer-Giraud, U, Meerpohl, H G

“…Carboplatin has proven efficacy in the treatment of ovarian cancer and has been proven to be less toxic compared to the parent compound cisplatin…”
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Paclitaxel-Induced “Recall” Soft Tissue Ulcerations Occurring at the Site of Previous Subcutaneous Administration of Paclitaxel in Low Doses by du Bois, A., Kommoss, F.G.M., Pfisterer, J., Lück, H.J., Meerpohl, H.G.

“…The presented case reports a rare complication of paclitaxel misuse: recall soft tissue injury at the site of previous subcutaneous paclitaxel administration…”
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Role of prostaglandins on the regulation of macrophage proliferation and cytotoxic functions by Meerpohl, H G, Bauknecht, T

“…The data presented show different effects of prostaglandins on proliferation and cytotoxic effector functions of murine bone-marrow derived mononuclear cells…”
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Formation of prostaglandins by ovarian carcinomas by Bauknecht, T, Siegel, A, Meerpohl, H G, Zahradnik, H P

“…Tissue contents of prostaglandins (PG) PGE2, PGE2a and 6-keto-PGF1a (degradation product of PGI2) were determined in specimens of advanced human ovarian cancer…”
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Chemotherapy for stage III-IV ovarian cancer: the CAP-regimen in previously untreated patients by Meerpohl, H G, Pfleiderer, A, Kleine, W, Teufel, G

“…Twenty-nine patients with advanced previously untreated epithelial ovarian cancer (FIGO stage III + IV) received induction chemotherapy with CAP…”
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