Search Results - "Meeran, Mohamed Fizur Nagoor"

Myrcene Salvages Rotenone-Induced Loss of Dopaminergic Neurons by Inhibiting Oxidative Stress, Inflammation, Apoptosis, and Autophagy by Azimullah, Sheikh, Jayaraj, Richard L, Meeran, Mohamed Fizur Nagoor, Jalal, Fakhreya Y, Adem, Abdu, Ojha, Shreesh, Beiram, Rami

“…Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta, resulting in motor deficits. The exact…”
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Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development by Nagoor Meeran, Mohamed Fizur, Javed, Hayate, Al Taee, Hasan, Azimullah, Sheikh, Ojha, Shreesh K

“…Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline monoterpene phenol. It is one of the most important dietary constituents in…”
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Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise by Nagoor Meeran, Mohamed Fizur, Goyal, Sameer N, Suchal, Kapil, Sharma, Charu, Patil, Chandragouda R, Ojha, Shreesh K

“…Asiatic acid (AA) is a naturally occurring aglycone of ursane type pentacyclic triterpenoids. It is abundantly present in many edible and medicinal plants…”
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Plant Extracts and Phytochemicals Targeting α -Synuclein Aggregation in Parkinson's Disease Models by Javed, Hayate, Nagoor Meeran, Mohamed Fizur, Azimullah, Sheikh, Adem, Abdu, Sadek, Bassem, Ojha, Shreesh Kumar

“…α-Synuclein (α-syn) is a presynaptic protein that regulates the release of neurotransmitters from synaptic vesicles in the brain. α-Syn aggregates, including…”
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α-Bisabolol abrogates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and intrinsic pathway of apoptosis in rats by Nagoor Meeran, Mohamed Fizur, Laham, Farah, Azimullah, Sheikh, Tariq, Saeed, Ojha, Shreesh

“…Mitochondrial dysfunction plays crucial role in the pathologenesis of myocardial infarction (MI). The present study evaluated the protective effect of…”
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Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer's and Parkinson's Diseases by Javed, Hayate, Mohamed Fizur, Nagoor Meeran, Jha, Niraj Kumar, Ashraf, Ghulam Md, Ojha, Shreesh

“…The phytochemicals have antioxidant properties to counter the deleterious effects of oxidative stress in the central nervous system and can be a promising drug…”
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α-Bisabolol, a Dietary Sesquiterpene, Attenuates Doxorubicin-Induced Acute Cardiotoxicity in Rats by Inhibiting Cellular Signaling Pathways, Nrf2/Keap-1/HO-1, Akt/mTOR/GSK-3β, NF-κB/p38/MAPK, and NLRP3 Inflammasomes Regulating Oxidative Stress and Inflammatory Cascades by Nagoor Meeran, Mohamed Fizur, Arunachalam, Seenipandi, Azimullah, Sheikh, Saraswathiamma, Dhanya, Albawardi, Alia, Almarzooqi, Saeeda, Jha, Niraj Kumar, Subramanya, Sandeep, Beiram, Rami, Ojha, Shreesh

“…Cancer chemotherapy with doxorubicin (DOX) may have multiorgan toxicities including cardiotoxicity, and this is one of the major limitations of its clinical…”
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α-Bisabolol Attenuates NF-κB/MAPK Signaling Activation and ER-Stress-Mediated Apoptosis by Invoking Nrf2-Mediated Antioxidant Defense Systems against Doxorubicin-Induced Testicular Toxicity in Rats by Arunachalam, Seenipandi, Nagoor Meeran, Mohamed Fizur, Azimullah, Sheikh, Kumar Jha, Niraj, Saraswathiamma, Dhanya, Albawardi, Alia, Beiram, Rami, Ojha, Shreesh

“…The present study investigated the effects of α-bisabolol on DOX-induced testicular damage in rats. Testicular damage was induced in rats by injecting DOX…”
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Thymol attenuates altered lipid metabolism in β-adrenergic agonist induced myocardial infarcted rats by inhibiting tachycardia, altered electrocardiogram, apoptosis and cardiac hypertrophy by Nagoor Meeran, Mohamed Fizur, Jagadeesh, Govindan Sangaran, Selvaraj, Palanisamy

“…•Lipids and lipoproteins play a vital role in the pathology of MI.•ISO induced MI showed tachycardia, hypertrophy, altered ECG and altered lipid…”
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Carvacrol, a Plant Metabolite Targeting Viral Protease (M pro ) and ACE2 in Host Cells Can Be a Possible Candidate for COVID-19 by Javed, Hayate, Meeran, Mohamed Fizur Nagoor, Jha, Niraj Kumar, Ojha, Shreesh

“…The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in December 2019, resulting in the coronavirus disease-19…”
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Tannic Acid Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Inhibiting Inflammation, Oxidative Stress, Apoptosis, and Glutamate Toxicity in Rats by Azimullah, Sheikh, Meeran, Mohamed Fizur Nagoor, Ayoob, Khatija, Arunachalam, Seenipandi, Ojha, Shreesh, Beiram, Rami

“…Parkinson's disease (PD), a movement disorder, is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra…”
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Limonene, a Monoterpene, Mitigates Rotenone-Induced Dopaminergic Neurodegeneration by Modulating Neuroinflammation, Hippo Signaling and Apoptosis in Rats by Eddin, Lujain Bader, Azimullah, Sheikh, Jha, Niraj Kumar, Nagoor Meeran, Mohamed Fizur, Beiram, Rami, Ojha, Shreesh

“…Rotenone (ROT) is a naturally derived pesticide and a well-known environmental neurotoxin associated with induction of Parkinson's disease (PD). Limonene…”
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Therapeutic Potential of Plants and Plant Derived Phytochemicals against Acetaminophen-Induced Liver Injury by Subramanya, Sandeep B, Venkataraman, Balaji, Meeran, Mohamed Fizur Nagoor, Goyal, Sameer N, Patil, Chandragouda R, Ojha, Shreesh

“…Acetaminophen (APAP), which is also known as paracetamol or -acetyl- -aminophenol is a safe and potent drug for fever, pain and inflammation when used at its…”
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Protective effects of α‐bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol‐induced myocardial infarction: In vivo and in vitro evidences by Meeran, Mohamed Fizur Nagoor, Laham, Farah, Al‐Taee, Hasan, Azimullah, Sheikh, Ojha, Shreesh

“…The effect of α‐bisabolol on hemodyanimcs, lipid peroxidation, and nonenzymatic antioxidants was evaluated in isoproterenol‐induced myocardial infarction in…”
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Lycopodium Attenuates Loss of Dopaminergic Neurons by Suppressing Oxidative Stress and Neuroinflammation in a Rat Model of Parkinson's Disease by Jayaraj, Richard L, Beiram, Rami, Azimullah, Sheikh, Meeran, Mohamed Fizur Nagoor, Ojha, Shreesh K, Adem, Abdu, Jalal, Fakhreya Yousuf

“…Parkinson's disease, a chronic, age related neurodegenerative disorder, is characterized by a progressive loss of nigrostriatal dopaminergic neurons. Several…”
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Does Hypertension Affect the Recovery of Renal Functions after Reversal of Unilateral Ureteric Obstruction? by Hammad, Fayez T, Lubbad, Loay, Al-Salam, Suhail, Hammad, Waheed F, Yasin, Javed, Meeran, Mohamed Fizur Nagoor, Ojha, Shreesh, Arunachalam, Seenipandi, Hammad, Awwab F

“…Research has demonstrated that hypertension can lead to an exaggeration in the renal functional and histological changes caused by ureteral obstruction. These…”
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Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol-induced myocardial infarcted rats by Nagoor Meeran, Mohamed Fizur, Stanely Mainzen Prince, Ponnian

“…This study evaluates the protective effects of thymol on altered plasma lipid peroxidation products and nonenzymic antioxidants in isoproterenol (ISO)‐induced…”
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The Effect of Hypertension on the Recovery of Renal Dysfunction following Reversal of Unilateral Ureteral Obstruction in the Rat by Hammad, Fayez T, Lubbad, Loay, Al-Salam, Suhail, Yasin, Javed, Meeran, Mohamed Fizur Nagoor, Ojha, Shreesh, Hammad, Waheed F

“…Both ureteral obstruction (UO) and hypertension are common conditions that affect kidney functions. Hypertension and chronic kidney disease are closely…”
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Preventive effects of N-acetyl cysteine on lipids, lipoproteins and myocardial infarct size in isoproterenol induced myocardial infarcted rats: An in vivo and in vitro study by Nagoor Meeran, Mohamed Fizur, Stanely Mainzen Prince, Ponnian, Hidhayath Basha, Rafeek

“…The present study evaluated the preventive effects of N-acetyl cysteine in isoproterenol induced myocardial infarcted rats. Rats were pretreated with N-acetyl…”
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Protective effects of N-acetyl cysteine on lipid peroxide metabolism on isoproterenol-induced myocardial infarcted rats by Nagoor Meeran, Mohamed Fizur, Mainzen Prince, Ponnian Stanely

“…The present study was designed to evaluate the preventive effects of N‐acetyl cysteine on lipid peroxide metabolism in isoproterenol (ISO) induced myocardial…”
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