Search Results - "Meer, Adriaan J."

Treatment of HCV Infection by Targeting MicroRNA by Janssen, Harry L.A, Reesink, Hendrik W, Lawitz, Eric J, Zeuzem, Stefan, Rodriguez-Torres, Maribel, Patel, Keyur, van der Meer, Adriaan J, Patick, Amy K, Chen, Alice, Zhou, Yi, Persson, Robert, King, Barney D, Kauppinen, Sakari, Levin, Arthur A, Hodges, Michael R

“…In this phase 2 trial, an antisense oligonucleotide was tested in the treatment of chronic hepatitis C virus infection. The oligonucleotide was designed to…”
Get full text

Association Between Sustained Virological Response and All-Cause Mortality Among Patients With Chronic Hepatitis C and Advanced Hepatic Fibrosis by van der Meer, Adriaan J, Veldt, Bart J, Feld, Jordan J, Wedemeyer, Heiner, Dufour, Jean-François, Lammert, Frank, Duarte-Rojo, Andres, Heathcote, E. Jenny, Manns, Michael P, Kuske, Lorenz, Zeuzem, Stefan, Hofmann, W. Peter, de Knegt, Robert J, Hansen, Bettina E, Janssen, Harry L. A

“…CONTEXT Chronic hepatitis C virus (HCV) infection outcomes include liver failure, hepatocellular carcinoma (HCC), and liver-related death. OBJECTIVE To assess…”
Get full text

Goals of Treatment for Improved Survival in Primary Biliary Cholangitis: Treatment Target Should Be Bilirubin Within the Normal Range and Normalization of Alkaline Phosphatase by Murillo Perez, Carla F., Harms, Maren H., Lindor, Keith D., van Buuren, Henk R., Hirschfield, Gideon M., Corpechot, Christophe, van der Meer, Adriaan J., Feld, Jordan J., Gulamhusein, Aliya, Lammers, Willem J., Ponsioen, Cyriel Y., Carbone, Marco, Mason, Andrew L., Mayo, Marlyn J., Invernizzi, Pietro, Battezzati, Pier Maria, Floreani, Annarosa, Lleo, Ana, Nevens, Frederik, Kowdley, Kris V., Bruns, Tony, Dalekos, George N., Gatselis, Nikolaos K., Thorburn, Douglas, Trivedi, Palak J., Verhelst, Xavier, Parés, Albert, Janssen, Harry L.A., Hansen, Bettina E.

“…In primary biliary cholangitis (PBC), bilirubin and alkaline phosphatase (ALP) are widely established as independent predictors of prognosis. Current treatment…”
Get full text

Liver transplant‐free survival according to alkaline phosphatase and GLOBE score in patients with primary biliary cholangitis treated with ursodeoxycholic acid by Veer, Rozanne C., Harms, Maren H., Corpechot, Christophe, Thorburn, Douglas, Invernizzi, Pietro, Janssen, Harry L. A., Battezzati, Pier M., Nevens, Frederik, Lindor, Keith D., Floreani, Annarosa, Ponsioen, Cyriel Y., Mayo, Marlyn J., Parés, Albert, Mason, Andrew L., Kowdley, Kris V., Trivedi, Palak J., Hirschfield, Gideon M., Bruns, Tony, Dalekos, George N., Gatselis, Nikolaos K., Verhelst, Xavier, Lammers, Willem J., Hansen, Bettina E., Buuren, Henk R., Meer, Adriaan J.

“…Summary Background After 1 year of ursodeoxycholic acid (UDCA), patients with primary biliary cholangitis (PBC) may have a normal GLOBE score despite high…”
Get full text

Quality of life in Dutch patients with primary biliary cholangitis: Discrepancies between patients’ perspectives and objective disease parameters by Veer, Rozanne C., Hooff, Maria C., Silva, Geraldine, Harms, Maren H., Metselaar, Herold J., Willemse, José, Utomo, Elaine, Meer, Adriaan J.

“…Aim This study aims to assess the health‐related quality of life (HRQoL) in a Dutch population of patients with primary biliary cholangitis (PBC) in relation…”
Get full text

Evaluation of ear, nose, and throat‐screening in liver transplantation candidates: A retrospective cohort study by Beukman, Eline, Meer, Adriaan J., Takkenberg, R. Bart, Hoed, Caroline M. den, Nagtegaal, Andries Paul

“…Background Patients with end‐stage liver disease can be treated with a liver transplantation (LT). Before listing, candidates are subjected to a screening…”
Get full text

Optimizing therapy in primary biliary cholangitis: Alkaline phosphatase at six months identifies one‐year non‐responders and predicts survival by Murillo Perez, C. Fiorella, Ioannou, Stephanie, Hassanally, Iman, Trivedi, Palak J., Corpechot, Christophe, Meer, Adriaan J., Lammers, Willem J., Battezzati, Pier Maria, Lindor, Keith D., Nevens, Frederik, Kowdley, Kris V., Bruns, Tony, Cazzagon, Nora, Floreani, Annarosa, Mason, Andrew L., Gulamhusein, Aliya, Ponsioen, Cyriel Y., Carbone, Marco, Lleo, Ana, Mayo, Marlyn J., Dalekos, George N., Gatselis, Nikolaos K., Thorburn, Douglas, Verhelst, Xavier, Parés, Albert, Londoño, Maria‐Carlota, Janssen, Harry L. A., Invernizzi, Pietro, Vuppalanchi, Raj, Hirschfield, Gideon M., Hansen, Bettina E., Levy, Cynthia

“…Background and Aims Patients with primary biliary cholangitis (PBC) and insufficient response to ursodeoxycholic acid (UDCA), currently assessed after 1 year,…”
Get full text

Disease burden in primary sclerosing cholangitis in the Netherlands: A long‐term follow‐up study by Munster, Kim N., Mol, Bregje, Goet, Jorn C., Munster, Sanne N., Weersma, Rinse K., Vries, Annemarie C., Meer, Adriaan J., Inderson, Akin, Drenth, Joost P., Erpecum, Karel J., Boonstra, Kirsten, Beuers, Ulrich, Dijkgraaf, Marcel G. W., Ponsioen, Cyriel Y.

“…Background & Aims Primary sclerosing cholangitis (PSC) is a progressive, cholestatic liver disease which greatly impacts the lives of individuals. Burden of…”
Get full text

A Comparison of Prognostic Scores (Mayo, UK-PBC, and GLOBE) in Primary Biliary Cholangitis by Goet, Jorn C., Murillo Perez, Carla F., Harms, Maren H., Floreani, Annarosa, Cazzagon, Nora, Bruns, Tony, Prechter, Florian, Dalekos, George N., Verhelst, Xavier, Gatselis, Nikolaos K., Lindor, Keith D., Lammers, Willem J., Gulamhusein, Aliya, Reig, Anna, Carbone, Marco, Nevens, Frederik, Hirschfield, Gideon M., van der Meer, Adriaan J., van Buuren, Henk R., Hansen, Bettina E., Parés, Albert

“…Comparative data on scores that predict outcome in primary biliary cholangitis (PBC) are scarce. We aimed to assess and compare the prognostic value of the…”
Get full text

Substantial impact of the COVID-19 pandemic on the reported number of diagnosed chronic hepatitis C virus infections in the Netherlands, 2019-2021 by den Boogert, Elisabeth M, Veldhuijzen, Irene K, Generaal, Ellen, Prins, Maria, Sonneveld, Milan J, van der Meer, Adriaan J, Zantkuijl, Paul, van Benthem, Birgit H B, de Coul, Eline L M Op

“…The COVID-19 pandemic has widespread consequences for health facilities, social contacts, and health-seeking behaviour, affecting the incidence, diagnosis and…”
Get full text

Graft Steatosis and Donor Diabetes Mellitus Additively Impact on Recipient Outcomes After Liver Transplantation—A European Registry Study by Sonneveld, Milan J., Parouei, Fatemeh, den Hoed, Caroline, Jonge, Jeroen, Salarzaei, Morteza, Porte, Robert J., Janssen, Harry L. A., Rosner‐van Rosmalen, Marieke, Vogelaar, Serge, Meer, Adriaan J., Maan, Raoel, Murad, Sarwa Darwish, Polak, Wojciech G., Brouwer, Willem Pieter

“…ABSTRACT Background and Aims Biopsy‐proven severe graft steatosis is associated with adverse outcomes after liver transplantation. The concomitant presence of…”
Get full text

Importance of complete response for outcomes of pregnancy in patients with autoimmune hepatitis by Fischer, Susan E., Vries, Elsemieke S., Tushuizen, Maarten E., Boer, Ynto S., Meer, Adriaan J. P., Man, Robert A., Brouwer, Johannes T., Kuyvenhoven, Johan P., Klemt‐Kropp, Michael, Gevers, Tom J. G., Tjwa, Eric T. T. L., Kuiper, Edith M. M., Verhagen, Marc A. M. T., Friederich, Philip W., Hoek, Bart

“…Background and Aims While some articles describe outcome of pregnancy in autoimmune hepatitis (AIH), there are less data evaluating influence of AIH control on…”
Get full text

Improvement of platelets after SVR among patients with chronic HCV infection and advanced hepatic fibrosis by van der Meer, Adriaan J, Maan, Raoel, Veldt, Bart J, Feld, Jordan J, Wedemeyer, Heiner, Dufour, Jean-François, Lammert, Frank, Duarte-Rojo, Andres, Manns, Michael P, Zeuzem, Stefan, Hofmann, W Peter, de Knegt, Robert J, Hansen, Bettina E, Janssen, Harry LA

“…Background and Aims: Patients with chronic hepatitis C virus (HCV) infection may develop cirrhosis with portal hypertension, reflected by decreased platelet…”
Get full text

Assessment of Adherence to Clinical Guidelines in Patients with Chronic Hepatitis B by Katwaroe, Warshan K, Brakenhoff, Sylvia M, van der Spek, Daniël P C, de Knegt, Robert J, van Kleef, Laurens A, de Man, Robert A, van der Meer, Adriaan J P, Sonneveld, Milan J, The Icarus Study Group

“…Background and aims: Adherence to guidelines is associated with improved long-term outcomes in patients with chronic hepatitis B (CHB). We aimed to study the…”
Get full text

Extending our confidence in sustained virological response by Maan, Raoel, van der Meer, Adriaan J.

“…See Article on Page 817…”
Get full text

Interferon-free antiviral therapy for chronic hepatitis C among patients in the liver transplant setting by van Tilborg, Marjolein, MD, PhD, Maan, Raoel, MD, PhD, van der Meer, Adriaan J., MD, PhD, de Knegt, Robert J., MD, PhD

“…Abstract Chronic hepatitis C (HCV) infection remains a major public health problem with many infected individuals worldwide. The revolutionary discovery of…”
Get full text

Reversion of disease manifestations after HCV eradication by van der Meer, Adriaan J, Berenguer, Marina

“…Summary Chronic infection with the hepatitis C virus (HCV) may lead to hepatic fibrosis and eventually cirrhosis, at which stage, patients have a substantial…”
Get full text

B-cell activating factor and IL-21 levels predict treatment response in autoimmune hepatitis by Biewenga, Maaike, Heidt, Sebastiaan, Vergunst, Manon, Marijnissen, Camiel M.J., de Man, Rob A., van der Eijk, Annemiek A., van der Meer, Adriaan J., Trouw, Leendert A., van Hoek, Bart

“…Increased serum IgG and autoantibodies suggest involvement of B cells in autoimmune hepatitis (AIH). The aim of this study was to assess levels of B cell…”
Get full text

Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis by Harms, Maren H, de Veer, Rozanne C, Lammers, Willem J, Corpechot, Christophe, Thorburn, Douglas, Janssen, Harry L A, Lindor, Keith D, Trivedi, Palak J, Hirschfield, Gideon M, Pares, Albert, Floreani, Annarosa, Mayo, Marlyn J, Invernizzi, Pietro, Battezzati, Pier Maria, Nevens, Frederik, Ponsioen, Cyriel Y, Mason, Andrew L, Kowdley, Kris V, Hansen, Bettina E, Buuren, Henk R van, van der Meer, Adriaan J

“…The clinical benefit of ursodeoxycholic acid (UDCA) in primary biliary cholangitis (PBC) has never been reported in absolute measures. The aim of this study…”
Get more information

The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients by Brouwer, Willem P, van der Meer, Adriaan J, Boonstra, Andre, Pas, Suzan D, de Knegt, Robert J, de Man, Rob A, Hansen, Bettina E, ten Kate, Fiebo JW, Janssen, Harry LA

“…Background & Aims We aimed to assess the association between the patatin‐like phospholipase domain‐containing‐3 (PNPLA3) I148M polymorphism, liver histology…”
Get full text