Search Results - "Meens, Merlijn J P M T"

Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice by Chennupati, Ramesh, Meens, Merlijn J P M T, Marion, Vincent, Janssen, Ben J, Lamers, Wouter H, De Mey, Jo G R, Köhler, S Eleonore

“…Argininosuccinate synthetase (ASS) is essential for recycling L-citrulline, the by-product of NO synthase (NOS), to the NOS substrate L-arginine. Here, we…”
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Antihypertensive treatment differentially affects vascular sphingolipid biology in spontaneously hypertensive rats by Spijkers, Léon J A, Janssen, Ben J A, Nelissen, Jelly, Meens, Merlijn J P M T, Wijesinghe, Dayanjan, Chalfant, Charles E, De Mey, Jo G R, Alewijnse, Astrid E, Peters, Stephan L M

“…We have previously shown that essential hypertension in humans and spontaneously hypertensive rats (SHR), is associated with increased levels of ceramide and…”
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Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo by Meens, Merlijn J.P.M.T, Mattheij, Nadine J.A, Nelissen, Jelly, Lemkens, Pieter, Compeer, Matthijs G, Janssen, Ben J.A, De Mey, Jo G.R

“…Slow dissociation of endothelin 1 from its endothelin A receptors is responsible for the long-lasting vasoconstrictor effects of the peptide. We showed…”
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Stimuli of Sensory-Motor Nerves Terminate Arterial Contractile Effects of Endothelin-1 by CGRP and Dissociation of ET-1/ETA-Receptor Complexes by Meens, Merlijn J. P. M. T., Compeer, Matthijs G., Hackeng, Tilman M., van Zandvoort, Marc A., Janssen, Ben J. A., De Mey, Jo G. R.

“…Background Endothelin-1 (ET-1), a long-acting paracrine mediator, is implicated in cardiovascular diseases but clinical trials with ET-receptor antagonists…”
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Calcitonin gene-related peptide selectively relaxes contractile responses to endothelin-1 in rat mesenteric resistance arteries by Meens, Merlijn J P M T, Fazzi, Gregorio E, van Zandvoort, Marc A, De Mey, Jo G R

“…We tested the hypothesis that endothelin-1 (ET-1) modulates sensory-motor nervous arterial relaxation by prejunctional and postjunctional mechanisms. Isolated…”
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Risky communication in atherosclerosis and thrombus formation by Meens, Merlijn J P M T, Pfenniger, Anna, Kwak, Brenda R

“…Atherosclerosis, a progressive disease of medium- and large-sized arteries, constitutes the major cause of death in developed countries, and is becoming…”
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ETA -receptor antagonists or allosteric modulators? by De Mey, Jo G.R, Compeer, Matthijs G, Lemkens, Pieter, Meens, Merlijn J.P.M.T

“…The paracrine signaling peptide endothelin-1 (ET1) is involved in cardiovascular diseases, cancer and chronic pain. It acts on class A G-protein-coupled…”
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Stimuli of sensory-motor nerves terminate arterial contractile effects of endothelin-1 by CGRP and dissociation of ET-1/ET(A)-receptor complexes by Meens, Merlijn J P M T, Compeer, Matthijs G, Hackeng, Tilman M, van Zandvoort, Marc A, Janssen, Ben J A, De Mey, Jo G R

“…Endothelin-1 (ET-1), a long-acting paracrine mediator, is implicated in cardiovascular diseases but clinical trials with ET-receptor antagonists were not…”
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Dual neural peptidase/endothelin-converting enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J.P.M.T, Janssen, Ben J.A, Schiffers, Paul M.H, De Mey, Jo G.R

“…BACKGROUND:Endothelin-1 (ET1) is a potent vasoconstrictor peptide with pro-mitogenic and pro-inflammatory properties and is therefore of interest in the…”
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Stimuli of Sensory-Motor Nerves Terminate Arterial Contractile Effects of Endothelin-1 by CGRP and Dissociation of ET-1/ET.sub.A-Receptor Complexes by Meens, Merlijn J. P. M. T, Compeer, Matthijs G, Hackeng, Tilman M, van Zandvoort, Marc A, Janssen, Ben J. A, De Mey, Jo G. R

“…Background Endothelin-1 (ET-1), a long-acting paracrine mediator, is implicated in cardiovascular diseases but clinical trials with ET-receptor antagonists…”
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Impaired flow-induced arterial remodeling in DOCA-salt hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J P M T, Fazzi, Gregorio E, Janssen, Ger J M, Debets, Jacques J M, Janssen, Ben J A, Schiffers, Paul M H, De Mey, Jo G R

“…Arteries from young healthy animals respond to chronic changes in blood flow and blood pressure by structural remodeling. We tested whether the ability to…”
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Dual neural endopeptidase/endothelin-converting [corrected] enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J P M T, Janssen, Ben J A, Schiffers, Paul M H, De Mey, Jo G R

“…Endothelin-1 (ET1) is a potent vasoconstrictor peptide with pro-mitogenic and pro-inflammatory properties and is therefore of interest in the development of…”
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