Search Results - "Meeks, Christina"

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  1. 1

    Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling by Tripathi, Rakshamani, Liu, Zulong, Jain, Aditi, Lyon, Anastasia, Meeks, Christina, Richards, Dana, Liu, Jinpeng, He, Daheng, Wang, Chi, Nespi, Marika, Rymar, Andrey, Wang, Peng, Wilson, Melissa, Plattner, Rina

    Published in Nature communications (29-10-2020)
    “…Metastatic melanoma remains an incurable disease for many patients due to the limited success of targeted and immunotherapies. BRAF and MEK inhibitors reduce…”
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    Journal Article
  2. 2

    ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization by Lyon, Anastasia, Tripathi, Rakshamani, Meeks, Christina, He, Daheng, Wu, Yuanyuan, Liu, Jinpeng, Wang, Chi, Chen, Jing, Zhu, Haining, Mukherjee, Sujata, Ganguly, Saptadwipa, Plattner, Rina

    Published in Cancers (02-02-2023)
    “…Melanomas harboring mutations are a particularly aggressive and deadly subtype. If patients cannot tolerate or the melanomas are insensitive to immune…”
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    Journal Article