Search Results - "Meeker, Harry C."

Induction of Toll-Like Receptor 9 Signaling as a Method for Ameliorating Alzheimer's Disease-Related Pathology by Scholtzova, Henrieta, Kascsak, Richard J, Bates, Kristyn A, Boutajangout, Allal, Kerr, Daniel J, Meeker, Harry C, Mehta, Pankaj D, Spinner, Daryl S, Wisniewski, Thomas

“…The pathogenesis of Alzheimer's disease (AD) is thought to be related to the accumulation of amyloid beta (Abeta) in amyloid deposits and toxic oligomeric…”
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Novel Epigenetic Regulation of Alpha-Synuclein Expression in Down Syndrome by Ramakrishna, Narayan, Meeker, Harry C., Brown, W. Ted

“…Alpha-synuclein ( SNCA ), a presynaptic protein, is significantly reduced in individuals with Down syndrome (DS) and Ts65Dn mice, a mouse model of DS…”
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Copper Chelation Delays the Onset of Prion Disease by Sigurdsson, Einar M., Brown, David R., Alim, Muhammad A., Scholtzova, Henrieta, Carp, Richard, Meeker, Harry C., Prelli, Frances, Frangione, Blas, Wisniewski, Thomas

“…The prion protein (PrP) binds copper and under some conditions copper can facilitate its folding into a more protease resistant form. Hence, copper levels may…”
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Clearance and prevention of prion infection in cell culture by anti-PrP antibodies by Pankiewicz, Joanna, Prelli, Frances, Sy, Man-Sun, Kascsak, Richard J., Kascsak, Regina B., Spinner, Daryl S., Carp, Richard I., Meeker, Harry C., Sadowski, Marcin, Wisniewski, Thomas

“…Prion diseases are transmissible and invariably fatal neurodegenerative disorders associated with a conformational transformation of the cellular prion protein…”
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Assessment of social interaction and anxiety-like behavior in senescence-accelerated-prone and -resistant mice by Meeker, Harry C, Chadman, Kathryn K, Heaney, Agnes T, Carp, Richard I

“…Abstract Two members of the senescence-accelerated mouse group, SAMP8 and SAMP10, are characterized by learning and memory deficits, while the SAMR1 strain is…”
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Immunization Delays the Onset of Prion Disease in Mice by Sigurdsson, Einar M., Brown, David R., Daniels, Maki, Kascsak, Richard J., Kascsak, Regina, Carp, Richard, Meeker, Harry C., Frangione, Blas, Wisniewski, Thomas

“…The outbreak of new variant Creutzfeldt-Jakob disease has raised the specter of a potentially large population being at risk to develop this prionosis. None of…”
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Accelerated Prion Disease Pathogenesis in Toll-Like Receptor 4 Signaling-Mutant Mice by Spinner, Daryl S, Cho, In Soo, Park, Seung Yong, Kim, Jae Il, Meeker, Harry C, Ye, Xuemin, Lafauci, Giuseppe, Kerr, Daniel J, Flory, Michael J, Kim, Bo Sook, Kascsak, Regina B, Wisniewski, Thomas, Levis, William R, Schuller-Levis, Georgia B, Carp, Richard I, Park, Eunkyue, Kascsak, Richard J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CpG oligodeoxynucleotide-enhanced humoral immune response and production of antibodies to prion protein PrPSc in mice immunized with 139A scrapie-associated fibrils by Spinner, Daryl S., Kascsak, Regina B., LaFauci, Giuseppe, Meeker, Harry C., Ye, Xuemin, Flory, Michael J., Kim, Jae Il, Schuller‐Levis, Georgia B., Levis, William R., Wisniewski, Thomas, Carp, Richard I., Kascsak, Richard J.

“…Prion diseases are characterized by conversion of the cellular prion protein (PrPC) to a protease‐resistant conformer, the srapie form of PrP (PrPSc). Humoral…”
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Scrapie infection activates the replication of ecotropic, xenotropic, and polytropic murine leukemia virus (MuLV) in brains and spinal cords of senescence-accelerated mice: Implication of MuLV in progression of scrapie pathogenesis by Lee, Kyung-Hee, Jeong, Byung-Hoon, Jin, Jae-Kwang, Meeker, Harry C., Kim, Jae-Il, Carp, Richard I., Kim, Yong-Sun

“…Senescence-accelerated mice (SAMP8) have a short life span, whereas SAMR1 mice are resistant to accelerated senescence. Previously it has been reported that…”
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Physiological properties of astroglial cell lines derived from mice with high (SAMP8) and low (SAMR1, ICR) levels of endogenous retrovirus by Kim, Boe-Hyun, Meeker, Harry C, Shin, Hae-Young, Kim, Jae-Il, Jeong, Byung-Hoon, Choi, Eun-Kyoung, Carp, Richard I, Kim, Yong-Sun

“…Previous studies have reported that various inbred SAM mouse strains differ markedly with regard to a variety of parameters, such as capacity for learning and…”
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Regulation of α-synuclein expression in down syndrome by Ramakrishna, Narayan, Meeker, Harry C., Patel, Satyam, Brown, Ted W., El Idrissi, Abdeslem

“…The triplication of genes located on chromosome 21 is known to cause a wide spectrum of pathology seen in Down syndrome (DS), including leukemia, seizures,…”
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Passage of chronic wasting disease prion into transgenic mice expressing Rocky Mountain elk (Cervus elaphus nelsoni) PrPC by LaFauci, Giuseppe, Carp, Richard I, Meeker, Harry C, Ye, Xuemin, Kim, Jae I, Natelli, Michael, Cedeno, Marisol, Petersen, Robert B, Kascsak, Richard, Rubenstein, Richard

“…1 New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA 2 Case Western Reserve…”
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Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie by Aucouturier, P, Geissmann, F, Damotte, D, Saborio, G P, Meeker, H C, Kascsak, R, Carp, R I, Wisniewski, T

“…Transmissible spongiform encephalopathies display long incubation periods at the beginning of which the titer of infectious agents (prions) increases in…”
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Anti-prion antibodies for prophylaxis following prion exposure in mice by Sigurdsson, Einar M., Sy, Man-Sun, Li, Ruliang, Scholtzova, Henrieta, Kascsak, Richard J., Kascsak, Regina, Carp, Richard, Meeker, Harry C., Frangione, Blas, Wisniewski, Thomas

“…Prion disease is characterized by a conformational change of the normal form of the prion protein (PrP C) to the scrapie-associated form (PrP Sc). Since the…”
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The mouse model for scrapie: inoculation, clinical scoring, and histopathological techniques by Meeker, Harry C, Ye, Xuemin, Carp, Richard I

“…The mouse is a popular and versatile model for the study of scrapie and other transmissible spongiform encephalopathies. In this chapter, information is given…”
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Targeting Prion Amyloid Deposits In Vivo by SADOWSKI, MARCIN, PANKIEWICZ, JOANNA, SCHOLTZOVA, HENRIETA, TSAI, JULIA, LI, YONGSHENG, CARP, RICHARD I, MEEKER, HARRY C, GAMBETTI, PIERLUIGI, DEBNATH, MANIK, MATHIS, CHESTER A, SHAO, LI, GAN, WEN-BIAO, KLUNK, WILLIAM E, WISNIEWSKI, THOMAS

“…The diagnosis of prion diseases in humans is challenging due to a lack of specific and sensitive non-invasive tests. Many forms of human prion disease…”
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Toll-like receptor 9 ligand CpG ODN as a new highly effective agent for prevention and/or treatment of Alzheimer's disease by Scholtzova, Henrieta, Kascsak, Richard J, Bates, Kristyn A, Boutajangout, Allal, Kerr, Daniel J, Meeker, Harry C, Mehta, Pankaj D, Spinner, Daryl S, Wisniewski, Thomas

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P3-409: The establishment of astrocyte cell models expressing endogenous MuLV from SAM mice by Kim, Boe-Hyun, Shin, Hae-Young, Meeker, Harry C, Kim, Jae-Il, Jeong, Byung-Hoon, Choi, Eun-Kyoung, Carp, Richard I, Kim, Yong-Sun

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Immunogold study of altered expression of some interendothelial junctional molecules in the brain blood microvessels of diabetic scrapie-infected mice by Vorbrodt, Andrzej W, Dobrogowska, Danuta H, Tarnawski, Michal, Meeker, Harry C, Carp, Richard I

“…Quantitative immunogold procedure was used to study the distribution of molecular components of interendothelial junctions in blood-brain barrier (BBB)…”
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In vivo micro magnetic resonance imaging signal changes in scrapie infected mice by Sadowski, Marcin, Tang, Cheuk Ying, Aguinaldo, Juan Gilberto, Carp, Richard, Meeker, Harry C., Wisniewski, Thomas

“…Signal abnormalities on magnetic resonance imaging (MRI) T2-weighted images (T2WI) have been described in patients with Creutzfeldt–Jakob disease; however, the…”
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