Search Results - "Meehan, J"

A phylogenomic view of ecological specialization in the Lachnospiraceae, a family of digestive tract-associated bacteria by Meehan, Conor J, Beiko, Robert G

“…Several bacterial families are known to be highly abundant within the human microbiome, but their ecological roles and evolutionary histories have yet to be…”
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Global chemical effects of the microbiome include new bile-acid conjugations by Quinn, Robert A., Melnik, Alexey V., Vrbanac, Alison, Fu, Ting, Patras, Kathryn A., Christy, Mitchell P., Bodai, Zsolt, Belda-Ferre, Pedro, Tripathi, Anupriya, Chung, Lawton K., Downes, Michael, Welch, Ryan D., Quinn, Melissa, Humphrey, Greg, Panitchpakdi, Morgan, Weldon, Kelly C., Aksenov, Alexander, da Silva, Ricardo, Avila-Pacheco, Julian, Clish, Clary, Bae, Sena, Mallick, Himel, Franzosa, Eric A., Lloyd-Price, Jason, Bussell, Robert, Thron, Taren, Nelson, Andrew T., Wang, Mingxun, Leszczynski, Eric, Vargas, Fernando, Gauglitz, Julia M., Meehan, Michael J., Gentry, Emily, Arthur, Timothy D., Komor, Alexis C., Poulsen, Orit, Boland, Brigid S., Chang, John T., Sandborn, William J., Lim, Meerana, Garg, Neha, Lumeng, Julie C., Xavier, Ramnik J., Kazmierczak, Barbara I., Jain, Ruchi, Egan, Marie, Rhee, Kyung E., Ferguson, David, Raffatellu, Manuela, Vlamakis, Hera, Haddad, Gabriel G., Siegel, Dionicio, Huttenhower, Curtis, Mazmanian, Sarkis K., Evans, Ronald M., Nizet, Victor, Knight, Rob, Dorrestein, Pieter C.

“…A mosaic of cross-phylum chemical interactions occurs between all metazoans and their microbiomes. A number of molecular families that are known to be produced…”
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Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues by Meehan, Conor J., Goig, Galo A., Kohl, Thomas A., Verboven, Lennert, Dippenaar, Anzaan, Ezewudo, Matthew, Farhat, Maha R., Guthrie, Jennifer L., Laukens, Kris, Miotto, Paolo, Ofori-Anyinam, Boatema, Dreyer, Viola, Supply, Philip, Suresh, Anita, Utpatel, Christian, van Soolingen, Dick, Zhou, Yang, Ashton, Philip M., Brites, Daniela, Cabibbe, Andrea M., de Jong, Bouke C., de Vos, Margaretha, Menardo, Fabrizio, Gagneux, Sebastien, Gao, Qian, Heupink, Tim H., Liu, Qingyun, Loiseau, Chloé, Rigouts, Leen, Rodwell, Timothy C., Tagliani, Elisa, Walker, Timothy M., Warren, Robin M., Zhao, Yanlin, Zignol, Matteo, Schito, Marco, Gardy, Jennifer, Cirillo, Daniela M., Niemann, Stefan, Comas, Inaki, Van Rie, Annelies

“…Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed from a research tool to a clinical application for the diagnosis and…”
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Molecular cartography of the human skin surface in 3D by Bouslimani, Amina, Porto, Carla, Rath, Christopher M., Wang, Mingxun, Guo, Yurong, Gonzalez, Antonio, Berg-Lyon, Donna, Ackermann, Gail, Christensen, Gitte Julie Moeller, Nakatsuji, Teruaki, Zhang, Lingjuan, Borkowski, Andrew W., Meehan, Michael J., Dorrestein, Kathleen, Gallo, Richard L., Bandeira, Nuno, Knight, Rob, Alexandrov, Theodore, Dorrestein, Pieter C.

“…Significance The paper describes the implementation of an approach to study the chemical makeup of human skin surface and correlate it to the microbes that…”
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Genomic characterization of Nontuberculous Mycobacteria by Fedrizzi, Tarcisio, Meehan, Conor J., Grottola, Antonella, Giacobazzi, Elisabetta, Fregni Serpini, Giulia, Tagliazucchi, Sara, Fabio, Anna, Bettua, Clotilde, Bertorelli, Roberto, De Sanctis, Veronica, Rumpianesi, Fabio, Pecorari, Monica, Jousson, Olivier, Tortoli, Enrico, Segata, Nicola

“…Mycobacterium tuberculosis and Mycobacterium leprae have remained, for many years, the primary species of the genus Mycobacterium of clinical and…”
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Poor Individual Risk Classification From Adverse Childhood Experiences Screening by Meehan, Alan J., Baldwin, Jessie R., Lewis, Stephanie J., MacLeod, Jelena G., Danese, Andrea

“…Adverse childhood experiences confer an increased risk for physical and mental health problems across the population, prompting calls for routine clinical…”
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GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions by Farhat, Maha R., Freschi, Luca, Calderon, Roger, Ioerger, Thomas, Snyder, Matthew, Meehan, Conor J., de Jong, Bouke, Rigouts, Leen, Sloutsky, Alex, Kaur, Devinder, Sunyaev, Shamil, van Soolingen, Dick, Shendure, Jay, Sacchettini, Jim, Murray, Megan

“…Drug resistance diagnostics that rely on the detection of resistance-related mutations could expedite patient care and TB eradication. We perform minimum…”
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Implantable biosensors and their contribution to the future of precision medicine by Gray, M., Meehan, J., Ward, C., Langdon, S.P., Kunkler, I.H., Murray, A., Argyle, D.

“…•Precision medicine takes individual variability into account in disease management.•Implantable biosensors have important applications in precision…”
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Reconstituting the genus Mycobacterium by Meehan, Conor J, Barco, Roman A, Loh, Yong-Hwee E, Cogneau, Sari, Rigouts, Leen

“…The definition of a genus has wide-ranging implications both in terms of binomial species names and also evolutionary relationships. In recent years, the…”
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ReDU: a framework to find and reanalyze public mass spectrometry data by Jarmusch, Alan K., Wang, Mingxun, Aceves, Christine M., Advani, Rohit S., Aguirre, Shaden, Aksenov, Alexander A., Aleti, Gajender, Aron, Allegra T., Bauermeister, Anelize, Bolleddu, Sanjana, Bouslimani, Amina, Caraballo Rodriguez, Andres Mauricio, Chaar, Rama, Coras, Roxana, Elijah, Emmanuel O., Ernst, Madeleine, Gauglitz, Julia M., Gentry, Emily C., Husband, Makhai, Jarmusch, Scott A., Jones, Kenneth L., Kamenik, Zdenek, Le Gouellec, Audrey, Lu, Aileen, McCall, Laura-Isobel, McPhail, Kerry L., Meehan, Michael J., Melnik, Alexey V., Menezes, Riya C., Montoya Giraldo, Yessica Alejandra, Nguyen, Ngoc Hung, Nothias, Louis Felix, Nothias-Esposito, Mélissa, Panitchpakdi, Morgan, Petras, Daniel, Quinn, Robert A., Sikora, Nicole, van der Hooft, Justin J. J., Vargas, Fernando, Vrbanac, Alison, Weldon, Kelly C., Knight, Rob, Bandeira, Nuno, Dorrestein, Pieter C.

“…We present ReDU ( https://redu.ucsd.edu/ ), a system for metadata capture of public mass spectrometry-based metabolomics data, with validated controlled…”
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The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia by Gröschel, Matthias I., Meehan, Conor J., Barilar, Ivan, Diricks, Margo, Gonzaga, Aitor, Steglich, Matthias, Conchillo-Solé, Oscar, Scherer, Isabell-Christin, Mamat, Uwe, Luz, Christian F., De Bruyne, Katrien, Utpatel, Christian, Yero, Daniel, Gibert, Isidre, Daura, Xavier, Kampmeier, Stefanie, Rahman, Nurdyana Abdul, Kresken, Michael, van der Werf, Tjip S., Alio, Ifey, Streit, Wolfgang R., Zhou, Kai, Schwartz, Thomas, Rossen, John W. A., Farhat, Maha R., Schaible, Ulrich E., Nübel, Ulrich, Rupp, Jan, Steinmann, Joerg, Niemann, Stefan, Kohl, Thomas A.

“…Recent studies portend a rising global spread and adaptation of human- or healthcare-associated pathogens. Here, we analyse an international collection of the…”
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Enzymatic Synthesis of Resorcylic Acid Lactones by Cooperation of Fungal Iterative Polyketide Synthases Involved in Hypothemycin Biosynthesis by Zhou, Hui, Qiao, Kangjian, Gao, Zhizeng, Meehan, Michael J, Li, Jesse W.-H, Zhao, Xiling, Dorrestein, Pieter C, Vederas, John C, Tang, Yi

“…Hypothemycin is a macrolide protein kinase inhibitor from the fungus Hypomyces subiculosus. During biosynthesis, its carbon framework is assembled by two…”
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The new phylogeny of the genus Mycobacterium: The old and the news by Tortoli, Enrico, Fedrizzi, Tarcisio, Meehan, Conor J., Trovato, Alberto, Grottola, Antonella, Giacobazzi, Elisabetta, Serpini, Giulia Fregni, Tagliazucchi, Sara, Fabio, Anna, Bettua, Clotilde, Bertorelli, Roberto, Frascaro, Francesca, De Sanctis, Veronica, Pecorari, Monica, Jousson, Olivier, Segata, Nicola, Cirillo, Daniela M.

“…Phylogenetic studies of bacteria have been based so far either on a single gene (usually the 16S rRNA) or on concatenated housekeeping genes. For what concerns…”
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Interactions in the microbiome: communities of organisms and communities of genes by Boon, Eva, Meehan, Conor J., Whidden, Chris, Wong, Dennis H.-J., Langille, Morgan G.I., Beiko, Robert G.

“…Abstract A central challenge in microbial community ecology is the delineation of appropriate units of biodiversity, which can be taxonomic, phylogenetic, or…”
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Genome-based taxonomic revision detects a number of synonymous taxa in the genus Mycobacterium by Tortoli, Enrico, Meehan, Conor J., Grottola, Antonella, Fregni Serpini, Giulia, Fabio, Anna, Trovato, Alberto, Pecorari, Monica, Cirillo, Daniela M.

“…The aim of this study was to clarify the taxonomic status of named species within the genus Mycobacterium. The analysis of genomes belonging to 174 taxa…”
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Visual clues act as a substitute for haptic feedback in robotic surgery by Hagen, M. E., Meehan, J. J., Inan, I., Morel, P.

“…Objective The lack of haptic feedback (HF) in robotic surgery is one of the major concerns of novice surgeons to that field. The superior visual appearances…”
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Pediatric robotic surgery: A single-institutional review of the first 100 consecutive cases by Meehan, John J., Sandler, Anthony

“…Background Robotic surgery is a new technology which may expand the variety of operations a surgeon can perform with minimally invasive techniques. We present…”
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Biochemical Establishment and Characterization of EncM’s Flavin-N5-oxide Cofactor by Teufel, Robin, Stull, Frederick, Meehan, Michael J, Michaudel, Quentin, Dorrestein, Pieter C, Palfey, Bruce, Moore, Bradley S

“…The ubiquitous flavin-dependent monooxygenases commonly catalyze oxygenation reactions by means of a transient C4a–peroxyflavin. A recent study, however,…”
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Carbon dioxide levels in neonates: what are safe parameters? by Wong, Sie Kei, Chim, M., Allen, J., Butler, A., Tyrrell, J., Hurley, T., McGovern, M., Omer, M., Lagan, N., Meehan, J., Cummins, E. P., Molloy, E. J.

“…There is no consensus on the optimal pCO 2 levels in the newborn. We reviewed the effects of hypercapnia and hypocapnia and existing carbon dioxide thresholds…”
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Comparison of in silico predicted Mycobacterium tuberculosis spoligotypes and lineages from whole genome sequencing data by Napier, Gary, Couvin, David, Refrégier, Guislaine, Guyeux, Christophe, Meehan, Conor J., Sola, Christophe, Campino, Susana, Phelan, Jody, Clark, Taane G.

“…Bacterial strain-types in the Mycobacterium tuberculosis complex underlie tuberculosis disease, and have been associated with drug resistance,…”
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